Navigation Links
Ceramide Directs Stem Cells in Embryo

Ceramide, a little-known lipid plays a crucial role in shaping a hollow sphere of stem cells into human beings, researchers have found. It seems to help in organizing// tissues by directing stem cells to their respective positions.

They found that in the first few days of life, ceramide helps stem cells line up to form the primitive ectoderm from which embryonic tissues develop, says Dr. Erhard Bieberich, biochemist at the Medical College of Georgia.

Probably 90 percent of ceramide gathers at the top or apical end of these early stem cells, literally helping cells have direction. 'We have cell polarity, an up and down, a head and foot of the cell, and that is what ceramide most likely regulates,' says Dr. Bieberich. 'Cell polarity is absolutely essential for differentiation; otherwise you have a ball of cells, not organized tissue.'

In fact, we start out as a wad of cells, but within 24 hours, some cells die and others become part of the hollow sphere with an inner layer – the primitive ectoderm – that will further differentiate into an embryo, and an outer layer – the primitive endoderm – that sustains the embryo during development.

'Ceramide distributes to the apical end of the cell,' says Kannan Krishnamurthy, MCG graduate student and first author of the study published in the Feb. 2 issue of the Journal of Biological Chemistry. 'In this case, the basal end, or lower end, is attached to the outer layer while the apical end points toward the sphere’s cavity.'

Cells make ceramide, which researchers are finding has many different jobs in the developing and mature body. Like other lipids, it helps make up membranes throughout the body, it has an insulation role in the skin and it is a precursor for the protective coating of nerves, called myelin.

'There is more and more evidence that ceramide not only is a structural lipid but a messenger involved in signal transduction, in telling proteins what
'"/>




Page: 1 2

Related medicine news :

1. Ceramide can target and kill cancer cells
2. Rajasthan Directs Doctors to Prescribe Medicines by Generic Names
3. Thailand Directs Pharma Companies to Declare Production Cost of Drugs
4. Blood Cells Capable of Regenerating Liver
5. White Cells Count Can Predict Heart Attack Death Risk
6. Gene Therapy Destroys Pancreatic Cancer Cells
7. Stem Cells Have Few Mutations
8. Heart may pull Cells from Body to Self-repair
9. Cells critical for asthma development found
10. Vitamin D Wipes out Cancer Cells
11. Bone Marrow Cells Help Heart Attack Patients
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Ceramide Directs Stem Cells Embryo

(Date:10/31/2014)... St. Joseph, Missouri (PRWEB) October 31, 2014 ... prepare for school, one Midwest optometrist feels they may ... vision problems to affect areas like concentration, school performance ... events may be too brief to identify progressive vision ... Options, St. Joseph, Mo., announces a new initiative: The ...
(Date:10/31/2014)... Oct. 31, 2014 (HealthDay News) -- Obesity increases the ... black and Hispanic women, two new U.S. studies show. ... found being overweight or obese increased the risk for ... women. "We,ve known this for a long time ... also in Hispanic women," study author Esther John, a ...
(Date:10/31/2014)... Santa Barbara, CA (PRWEB) October 31, 2014 ... for holiday shoppers to find affordable but tasteful gifts for ... special 22nd Annual Early Bird Gift Giving Special , ... percent off when they purchase Wine Club Gift membership. ... to take advantage of this special. Besides offering discounts, Gold ...
(Date:10/31/2014)... 2014 Florida Air Academy, the ... in grades 6-12, is taking the lead when ... and concussions, becoming the first high school in ... Post-Concussion Assessment and Cognitive Testing) computerized assessment to ... lawsuit grabs the headlines, and the Centers for ...
(Date:10/31/2014)... 31, 2014 BCC Research ( http://www.bccresearch.com ) ... QUALITY MARKET , the U.S. indoor air quality (IAQ) market ... a compound annual growth rate (CAGR) of 7% over the ... grow at a CAGR of 7.4%. , Since 2012, ... mold, the outbreak of infectious diseases such as bird flu ...
Breaking Medicine News(10 mins):Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 2Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 3Health News:Study Confirms Obesity-Breast Cancer Link for Blacks, Hispanics 2Health News:Gold Medal Wine Club now offering Early Bird Gift Giving Special for Holidays 2Health News:Florida Air Academy Tackling Concussions Head-On 2Health News:Florida Air Academy Tackling Concussions Head-On 3Health News:Global Market for U.S. Indoor Air Quality (IAQ) to Reach $11.4 Billion by 2019; Equipment Market Segment Surging at 7.4% CAGR 2Health News:Global Market for U.S. Indoor Air Quality (IAQ) to Reach $11.4 Billion by 2019; Equipment Market Segment Surging at 7.4% CAGR 3
... , FRIDAY, Jan. 14 (HealthDay News) -- Obese ... doctors than obese white patients, a new study finds. ... Public Health also said they were surprised to find that ... to receive weight and exercise counseling than black patients treated ...
... A simple, automated method of tracking E. coli ... potentially contaminated bodies of water or waterways. The technique described ... and Drug Design could reduce the incidence of waterborne ... environmental and health problem. Water related diseases are the leading ...
... COLUMBUS, Ohio A new study by Ohio State ... cancer by combining two kinds of targeted agents, one ... and one that reverses changes that silence genes that ... available and being evaluated individually in clinical trials, the ...
... THURSDAY, Jan. 13 (HealthDay News) -- Home-based dialysis is an ... say. In a new study, researchers evaluated the impact ... the survival of 2,110 adult Canadian patients who had to ... were similar for both groups of patients during the initial ...
... Association today issued a call to action for the public, ... efforts to reduce the amount of sodium (salt) Americans consume ... Journal of the American Heart Association , the association sets ... the general population, which is to consume no more than ...
... , THURSDAY, Jan. 13 (HealthDay News) -- In an unscripted ... Tucson and America" memorial, President Barack Obama said Rep. Gabrielle ... and her husband Mark Kelly at University Medical Center in ... to House Minority Leader Nancy Pelosi (D-Calif.) confirmed that Pelosi, ...
Cached Medicine News:Health News:Is Race a Factor in Obesity Counseling? 2Health News:Speeding up E. coli detection 2Health News:Study provides molecular rationale for combining targeted agents to treat breast cancer 2Health News:Dialysis Options Remain After Kidney Transplant Failure 2Health News:Population-wide reduction in salt consumption recommended 2Health News:Population-wide reduction in salt consumption recommended 3Health News:Giffords Opens Eyes. Like 'Watching a Miracle,' Friends Say 2Health News:Giffords Opens Eyes. Like 'Watching a Miracle,' Friends Say 3
(Date:10/30/2014)... , Oct. 30, 2014 /CNW/ - Atlantic Canadians ... agreement reached between Canada,s provinces ... Keon , President of the Canadian Generic Pharmaceutical Association ... the comments while speaking at the Atlantic Summit on ... , which is being hosted by the Public ...
(Date:10/30/2014)... Stryker Orthopaedics, the Official Joint Replacement Products ... out its debut year of the relationship at the ... This marks the eleventh tournament stop along ... brand has activated on-site with the "Stryker Mobility Zone" ... the importance of joint health.  The ...
(Date:10/30/2014)... Oct. 30, 2014 WuXi PharmaTech (Cayman) Inc. (NYSE: ... and technology platform company serving the pharmaceutical, biotechnology, and ... and the United States ... in the Tel Aviv area ... promote WuXi,s broad platform of integrated R&D services to ...
Breaking Medicine Technology:Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 2Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 3Stryker Mobility Zone Makes Final Stop Of 2014 At Charles Schwab Cup Championship 2Stryker Mobility Zone Makes Final Stop Of 2014 At Charles Schwab Cup Championship 3Stryker Mobility Zone Makes Final Stop Of 2014 At Charles Schwab Cup Championship 4WuXi AppTec Launches Representative Office in Israel, Forms Strategic Collaboration with Pontifax 2
... Oct. 26 /PRNewswire-Asia-FirstCall/ -- China Sky One Medical, ... (NASDAQ: CSKI ), a leading fully ... China ("PRC"), today announced that it has submitted, ... an application to China,s State Food and Drug ...
... an Alliance in... -- NEW YORK and CAMBRIDGE, Massachusetts, October 26, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we need ...
Cached Medicine Technology:China Sky One Medical Applies for Production Licenses of 15 New Medical Products 2China Sky One Medical Applies for Production Licenses of 15 New Medical Products 3Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 2Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 3Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 4Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 5Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 6Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 7Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 8Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 9Celtic Therapeutics and Resolvyx Pharmaceuticals Announce an Alliance in Ophthalmology 10
The RC-4000 guarantees precise and efficient multi-diagnostic measurement by combining keratometry, refraction, refraction/keratometry and contact lens base curve measurement....
... Rechargeable, cordless slit-lamp microscope ... purpose , Easy selection of slit ... , Extra-bright halogen lamp light source ... extra ,power pack , Supports digital ...
The PillCam™ ESO video capsule is specifically designed to view the inner lining of the Esophagus. The capsule is equipped with miniature cameras on both ends and is about the size of a multi-v...
World's first commercially available vacuum assisted biopsy device for MRI....
Medicine Products: