Navigation Links
Celiac Disease Sufferers See an End to their Misery

Celiac disease sufferers often endure a life of dietary restrictions, ensuring that no gluten, a product found in many commonly eaten foods//, ever passes their lips.

But this may soon come to an end. Researchers in the Netherlands have found that an enzyme originally developed for commercial food processing -- AN-PEP -- may be able to break down gluten in the stomach before it reaches the small intestine. This information could be vital because the small intestine is where celiac disease originates.

According to the study's lead author, Frits Konig, professor of immunology at Leiden University Medical Center "There is a realistic chance that this enzyme can be used to develop an alternative treatment for celiac disease. It is very difficult to predict if such an enzyme-based treatment would actually be preferred over a gluten-free diet, but at the very least, it would provide patients with the option to occasionally follow a normal diet -- for example, when going out or during other social occasions, times when a gluten-free diet is certainly bothersome.

The results of the research have been published in the online journal American Journal of Physiology - Gastrointestinal and Liver Physiology. .

According to Konig about 1 percent of people in the United States and Europe are affected by celiac disease which is an autoimmune disease. It occurs when the body mistakes gluten molecules as foreign invaders to be destroyed. As a result parts of the small intestine are also destroyed along with the gluten moleculesduring the immune system response. This leads to a difficulty for the small intestine to properly absorb nutrients from food causing anemia and vitamin deficiencies. .

Therefore the only solution for avoiding the flare up of this disease would be to avoid gluten completely. However this is not an easy task. As Konig pointed out, "Gluten is a common protein found in wheat and related cereals like barley and rye. This means many common food products, like bread, breakfast cereals, pasta, cookies, etc., are forbidden. Moreover, gluten is often used as an additive in the food industry, so, many products that are not normally associated with wheat may contain gluten"..

As there is no animal model for celiac disease, treatments cannot be studied in animals. .

Konig said, "AN-PEP is very efficient and completely breaks down gluten proteins into fragments that are so small that they can no longer cause inflammation in the intestine. This we have also demonstrated by using white blood cells from patients that respond to gluten and cause inflammation in the intestine. These cells no longer respond to gluten when it has been treated with the AN-PEP enzyme"..

According to Konig AN-PEP is derived from Aspergillus niger, a common fungus. Since Aspergillus niger is already used in commercial food processing, he said side effects were unlikely from the treatment.

Konig said the next step is to conduct human trials.


'"/>




Related medicine news :

1. Celiac Disease in Type 1 Diabetes
2. Research on Celiac Disease in children
3. Understanding The Link Between Celiac Disease And Osteoporosis
4. Scientists Discover Non-dietary Therapy For Celiac Diseases
5. Center for Celiac Disease Opens
6. Potential Link Between Celiac Disease and Cognitive Decline
7. Prevalence of Celiac disease in children with type 1 diabetes
8. From the frying pan into the fire: Celiac disease and diabetes
9. Gluten Free Bread: Boon for Celiac Disease
10. Research Finds No Link Found Between Autism and Celiac Disease
11. Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... CA (PRWEB) , ... September 22, 2017 , ... ... to help you brush more effectively even on the go. Their electric toothbrushes ... gingivitis and gum inflammation, with UV sanitizing technology. Combining leading edge Enke technology ...
(Date:9/22/2017)... ... September 22, 2017 , ... Global Lyme Alliance ... research, education and awareness, today announced the appointment of Timothy J. Sellati, Ph.D. ... Sellati has more than 20 years of research experience with Lyme and other ...
(Date:9/21/2017)... ... 21, 2017 , ... The American Addiction Treatment Association (AATA) ... in the addiction treatment industry entitled: Special Investigations Unit (SIU) – What ... state and federal governments are increasingly scrutinizing the addiction treatment industry for fraudulent ...
(Date:9/21/2017)... ... , ... In addition to sticking with the new years ... and use natural alternatives for all house cleaning products, disinfectants, respiratory relief, and ... the new line of essential oils, are all 100% organic and natural. , ...
(Date:9/21/2017)... RICHMOND, Va. (PRWEB) , ... September 21, 2017 ... ... Richmond with a different approach to addiction recovery at a time when Virginia ... 1,420 deaths resulting from drug overdose, a staggering increase of 38 percent from ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)...  Medical professionals are expected to continuously ... their patients. Medical simulations offer clinicians the ... Simulation provides a safe method for teaching ... refine techniques and build confidence, without putting ... such as augmented reality, will now provide ...
(Date:9/5/2017)... 5, 2017  Xyntek Inc. has announced another milestone in their continued growth ... to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West Adams Street, Suite ... Xyntek's ... ...
(Date:9/1/2017)... , Sept. 1, 2017  Explorers Like Us ( https://explorerslikeus.com/ ... greatest aural experiences — and deliver these experiences as part ... help people feel and heal better. ... While nothing beats a walk, jog ... your mind, Life Environments™ is the next best thing when ...
Breaking Medicine Technology: