Navigation Links
Celebrex- pros and cons

Though Celebrex reduces the possibility of growth of colon polyps to half, it doubles the risk of serious heart troubles.//

This was revealed by two significant studies published in the Aug. 31 issue of The New England Journal of Medicine. The opinions of Bruce M. Psaty, M.D., Ph.D., and John D. Potter, M.B., Ph.D., of the University of Washington were also published along with it.

"These two trials provide strong evidence that among patients with colonic adenomas, the use of celecoxib for up to three years reduces the risk of metachronous adenoma," Drs Bruce Psaty and John Potter.

"These placebo-controlled trials were too small to evaluate the role of celecoxib in preventing colorectal cancer. Nevertheless, in these same studies, significant cardiovascular risks were demonstrated. In patients with adenomas who undergo repeated colonoscopies, the increase in cardiovascular events caused by celecoxib outweighs what may be an optimistic projection of its potential benefit in decreasing colorectal-cancer events.”

Heart risks associated with Celebrex is being given a lot of importance by doctors. Celebrex belongs to the Cox-2 inhibitors, painkiller family. Vioxx and Bextra are the other members that are no longer available in the market due to their connection with heart disease.

Celebrex is not as dangerous as Vioxx. 200mgs a day is the common dosage of celebex. Though this dosage has never been associated with heart diseases or attacks, it does carry some risk when given along with all prescription anti-inflammatory drugs.Thus, FDA has necessitated a warning on the drug’s label.

Cox-2 inhibitors belong to the latest generation of the painkillers called NSAIDs (nonsteroidal anti-inflammatory drugs) whereas aspirin, ibuprofen, and naproxen are some of the older NSAIDs. The latter can cause stomach problems like ulcers. Cox-2 inhibitors are easier on the stomach than the older NSAIDs at low do sages.

Arthritis and other painful disorders are treated with Celebrex and other anti-inflammatory drugs. The patients with the help of their doctors should consider the advantages of these drugs against any likely risk. But for patients taking low doses of Celebrex for arthritis pain, it is more beneficial than harmful.

Celbrex has another function of preventing precancerous polyps in people with a rare condition called familial adenomatous polyposis. The risk of getting colon cancer is higher in this condition as there are more chances of polyps becoming cancerous. Celebrex, at a very high dose, is approved for the treatment.

But the advantages of Celebrex is overshadowed by the risk of heart problems in these people, because they are at a very high risk of colon cancer.
GA
'"/>




Related medicine news :

1. Simvastatin Plus Niacin May Lower Heart Risks
2. Ritalin May Lower Cocaine Abuse
3. Eating More Often May Help Lower Cholesterol
4. Lower surgical volume linked to higher death rate
5. Lowering blood pressure beneficial for PAD patients
6. Lower chance of bone fracture with Vitamin D supplementation
7. Tea Pill Lowers Cholesterol
8. Aspirin Lowers Leukemia Risk
9. Almonds Help Lower Cholesterol
10. Lowering Risk of Breast Cancer Recurrence
11. Drug to Lower Cholesterol Underused
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2017)... ... July 18, 2017 , ... ... its faster PICOPLUS 450 ps pulse width and a new published paper ... yttrium-aluminum-garnet lasers in tissue-mimicking phantom’ featured in Nature’s specialty journal Scientific Reports ...
(Date:7/17/2017)... ... July 17, 2017 , ... Summer camp season is ... ensure children are protected from Lyme and other tick-borne diseases. , With scientists ... increased risk not only for the tick-borne illness, but for its various debilitating ...
(Date:7/17/2017)... ... 17, 2017 , ... HMP , a leader in ... Texas Academy of Family Physicians (TAFP) for the 6th annual Cardiometabolic ... Hyatt Regency Dallas in Dallas, Texas.     , CRS and TAFP will collaborate to ...
(Date:7/17/2017)... ... July 17, 2017 , ... Jordan ... completed a nationwide executive search for Springfield Clinic’s Chief Executive Officer (CEO) in ... Williams, a skilled healthcare executive with more than 30 years of experience, as ...
(Date:7/17/2017)... CA (PRWEB) , ... July 17, 2017 , ... ProLayout ... These minimalistic layouts can be used to complement vlogs, professional productions, and to showcase ... click of a mouse. Manipulate camera controls to make beautiful and unique camera movements ...
Breaking Medicine News(10 mins):
(Date:7/5/2017)... Pace Analytical, a company of over 2,000 employees and a leader in environmental ... Sciences, further solidifying their position as the top American owned and operated environmental ... ... Analytical ... Mt Juliet, TN , enhances Pace Analytical,s capability as an innovative full ...
(Date:6/30/2017)... SAN DIEGO , June 30, 2017  AVACEN Medical (AVACEN) ... Access Journal. The research describes the use of its AVACEN ... by those suffering from fibromyalgia. ... AVACEN Medical ... Fibromyalgia is characterized by chronic widespread pain. It affects approximately 200 to ...
(Date:6/20/2017)... ROTTERDAM, Netherlands and LAGUNA HILLS, ... announced the presentation of new data that validate the ... to risk stratify patients with multiple myeloma (MM). In ... of the European Hematology Association (EHA) in ... prognostic value of MMprofiler for identifying high-risk elderly patients. ...
Breaking Medicine Technology: