Navigation Links
Celebrex- pros and cons

Though Celebrex reduces the possibility of growth of colon polyps to half, it doubles the risk of serious heart troubles.//

This was revealed by two significant studies published in the Aug. 31 issue of The New England Journal of Medicine. The opinions of Bruce M. Psaty, M.D., Ph.D., and John D. Potter, M.B., Ph.D., of the University of Washington were also published along with it.

"These two trials provide strong evidence that among patients with colonic adenomas, the use of celecoxib for up to three years reduces the risk of metachronous adenoma," Drs Bruce Psaty and John Potter.

"These placebo-controlled trials were too small to evaluate the role of celecoxib in preventing colorectal cancer. Nevertheless, in these same studies, significant cardiovascular risks were demonstrated. In patients with adenomas who undergo repeated colonoscopies, the increase in cardiovascular events caused by celecoxib outweighs what may be an optimistic projection of its potential benefit in decreasing colorectal-cancer events.”

Heart risks associated with Celebrex is being given a lot of importance by doctors. Celebrex belongs to the Cox-2 inhibitors, painkiller family. Vioxx and Bextra are the other members that are no longer available in the market due to their connection with heart disease.

Celebrex is not as dangerous as Vioxx. 200mgs a day is the common dosage of celebex. Though this dosage has never been associated with heart diseases or attacks, it does carry some risk when given along with all prescription anti-inflammatory drugs.Thus, FDA has necessitated a warning on the drug’s label.

Cox-2 inhibitors belong to the latest generation of the painkillers called NSAIDs (nonsteroidal anti-inflammatory drugs) whereas aspirin, ibuprofen, and naproxen are some of the older NSAIDs. The latter can cause stomach problems like ulcers. Cox-2 inhibitors are easier on the stomach than the older NSAIDs at low do sages.

Arthritis and other painful disorders are treated with Celebrex and other anti-inflammatory drugs. The patients with the help of their doctors should consider the advantages of these drugs against any likely risk. But for patients taking low doses of Celebrex for arthritis pain, it is more beneficial than harmful.

Celbrex has another function of preventing precancerous polyps in people with a rare condition called familial adenomatous polyposis. The risk of getting colon cancer is higher in this condition as there are more chances of polyps becoming cancerous. Celebrex, at a very high dose, is approved for the treatment.

But the advantages of Celebrex is overshadowed by the risk of heart problems in these people, because they are at a very high risk of colon cancer.
GA
'"/>




Related medicine news :

1. Simvastatin Plus Niacin May Lower Heart Risks
2. Ritalin May Lower Cocaine Abuse
3. Eating More Often May Help Lower Cholesterol
4. Lower surgical volume linked to higher death rate
5. Lowering blood pressure beneficial for PAD patients
6. Lower chance of bone fracture with Vitamin D supplementation
7. Tea Pill Lowers Cholesterol
8. Aspirin Lowers Leukemia Risk
9. Almonds Help Lower Cholesterol
10. Lowering Risk of Breast Cancer Recurrence
11. Drug to Lower Cholesterol Underused
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... ... May 03, 2016 , ... Elizabeth Murray has always loved walking one ... with one on her shoulder and one on her arm. But she got to ... years of mitral valve prolapse. , The valves of the heart wouldn’t close properly ...
(Date:5/3/2016)... Pasadena, CA (PRWEB) , ... May 03, 2016 ... ... tuition-free, accredited American online university, has announced today the launch of its Associates ... Nobel Laureate and President Emeritus of The Rockefeller University, Dr. Torsten N. Wiesel; ...
(Date:5/3/2016)... , ... May 03, 2016 , ... Boston Children’s Hospital ... rehearse tough medical situations or practice tricky or rare procedures in an environment that ... the SIM Center is also available to inventors and “hackers” to develop and test ...
(Date:5/3/2016)... ... 03, 2016 , ... Park Cities Pet Sitter has openings for both full-time ... 75205, 75206, 75209, 75219, 75220, 75225, 75229, 75230, 75231 and 75235 zip codes. ... Plano, Preston Hollow and Park Cities areas of the Metroplex. Candidates must love ...
(Date:5/3/2016)... York, NY (PRWEB) , ... May 03, 2016 ... ... solutions for the healthcare industry, announced today that Legacy Health is expanding its ... Efficient Works platform), after a highly successful initial proof of concept. The Portland, ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... 3, 2016 Intec Pharma Ltd. ... biopharmaceutical company, today announced the appointment of Pnina ... "Ms. Strauss-Levy has 15 years of experience ... an outstanding track record, having supported the advancement of ... processes in the United States ...
(Date:5/2/2016)... -- Leading Economies with Fastest Real GDP Annual Percentage Change, 2015  ... Ireland 7.8 India 7.3, , Source: IMF and TechSci Research ... of Brazil , Russia , ... , registered the fastest GDP growth during the first decade of the ... recession in Brazil and Russia , ...
(Date:4/29/2016)... 2016  In the next ten years, the ... systems dependent on CRTs monitors to those reliant on ... Medical monitors and will automatically sync to existing ... foreseeable benefits to this technological advancement, it also ... to be replaced in order to be LCD ...
Breaking Medicine Technology: