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Cancer Risk is High Among HIV/AIDS and Kidney Transplant Patients

Researchers have found that HIV/AIDS and kidney transplant patients are at higher risk of developing 20 different types of cancer than the general population.

The study was conducted by a team of researchers led by Professor Andrew Grulich at the University of New South Wales National Centre in HIV Epidemiology and Clinical Research (NCHECR).

As part of the study, scientists compared cancer rates between these HIV/AIDS and kidney transplant patients with the general population.

The study found that HIV/AIDS patients were 11 times more likely to develop Hodgkins lymphoma, a cancer associated with Epstein Barr Virus, while those who had a transplant were 4 times at a higher risk.

The study also found that in both these populations, cancers associated with human papilloma virus, from cervical cancer to cancers of the mouth, penis and anus were significantly increased.

One of the three cancers that were already linked with HIV is Kaposis sarcoma. In HIV population, there was a 3,640-fold increased likelihood for patients to develop the disease.

This research showed that transplant patients were 208 times more likely to develop the cancer than the general population.

Researchers suggested that one common thing in both the groups was immune deficiency, which was responsible for the increased risk of developing cancer.

The only thing that people with AIDS and transplant recipients share is immune deficiency, otherwise their risk factors for cancer differ markedly, the Lancet quoted Professor Grulich, as saying.

In other cancers, which are not linked with viruses, such as breast and prostate cancer, both groups had similar rates to the general population, he said.


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