Navigation Links
Cancer Patients are at High Risk for Potential Drug Interactions

Potential drug interactions from prescribed medications are common among cancer patients and may cause// unnecessary harm, according to a study in the April 18 Journal of the National Cancer Institute.

Cancer patients often take several medications at the same time, not only for treating their cancer but also for side effects and other secondary illnesses. Because of this, they can be at high risk for adverse drug interactions and duplicate medications. Consequences of these interactions can range from inactivation of cancer-fighting medications to severely injuring or killing the patient.

Rachel Riechelmann, M.D., of the Princess Margaret Hospital in Toronto, and colleagues gave 405 cancer patients a questionnaire about the medications they had taken in the last four weeks. Their responses were analyzed using a drug interaction software program that could identify potential interactions and rank them by severity.

Nearly a third of patients were exposed to at least one potential drug interaction. The researchers identified 276 drug combinations with the potential to interact. About nine percent of the interactions considered of major severity—risk of death—and 77 percent of moderate severity—risk of serious health problems. About eight percent of the patients received duplicate medications.

The researchers found that some of the drugs interacted with anticancer medications. The most common were warfarin (a drug to prevent blood clots), antihypertension drugs, aspirin and anticonvulsants. Warfarin stood out because it can cause hemorrhages when used with certain chemotherapy medications, and the interaction can interfere with its metabolism. Additionally, patients with brain tumors were at particularly high risk since they are often prescribed anticonvulsants.

"We suggest that patients at high risk… be routinely screened for potential drug interactions. The development of medication databases and computerize d physician medication order entry linked to screening electronic programs could help health professionals to identify dangerous drug combinations and monitor prescriptions of agents with high risks of interactions," the authors write.

In an accompanying editorial, Peter Norton, M.D., of the University of Calgary, and G. Ross Baker, Ph.D., of the University of Toronto, agree that a better system for tracking patients' medications is needed. "We believe that such coordination and communication have the potential to substantially reduce the incidence of and mitigate possible harm from the potential drug interactions that have been discovered by Riechelmann [and colleagues]. In other high-risk industries, such as aviation and the offshore oil industry, many errors result from poor coordination and communication, and in these areas, strategies to improve team coordination and communication have led to reductions in incidents," the authors write.

Source-Eurekalert
ME/V
'"/>




Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... (PRWEB) , ... June 27, 2016 , ... Quality metrics ... yet in many ways they remain in the eye of the beholder, according to ... a publication of The American Journal of Managed Care. For the full issue, ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/24/2016)... , ... June 24, 2016 , ... A recent ... most people are unfamiliar with. The article goes on to state that individuals are ... many of these less common operations such as calf and cheek reduction. The Los ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. ... The attorneys chosen by their peers for this recognition are considered among the top ... Shareholders received special honors as members of this year’s Legal Elite Hall of Fame: ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Ontario , June 27, 2016  VMS Rehab ... Company,s Board will take whatever measures required to build ... Company,s stock which is currently listed on the OTC ... Wexler, Company Chairman and CEO, "We are seeing an ... difficult to understand, not only by the Company, but ...
(Date:6/24/2016)... 24, 2016  Global Blood Therapeutics, Inc. (GBT) (NASDAQ: ... novel therapeutics for the treatment of grievous blood-based ... closing of its previously announced underwritten public offering ... public offering price of $18.75 per share. All ... by GBT. GBT estimates net proceeds from the ...
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
Breaking Medicine Technology: