Navigation Links
Cancer Patients are at High Risk for Potential Drug Interactions

Potential drug interactions from prescribed medications are common among cancer patients and may cause// unnecessary harm, according to a study in the April 18 Journal of the National Cancer Institute.

Cancer patients often take several medications at the same time, not only for treating their cancer but also for side effects and other secondary illnesses. Because of this, they can be at high risk for adverse drug interactions and duplicate medications. Consequences of these interactions can range from inactivation of cancer-fighting medications to severely injuring or killing the patient.

Rachel Riechelmann, M.D., of the Princess Margaret Hospital in Toronto, and colleagues gave 405 cancer patients a questionnaire about the medications they had taken in the last four weeks. Their responses were analyzed using a drug interaction software program that could identify potential interactions and rank them by severity.

Nearly a third of patients were exposed to at least one potential drug interaction. The researchers identified 276 drug combinations with the potential to interact. About nine percent of the interactions considered of major severity—risk of death—and 77 percent of moderate severity—risk of serious health problems. About eight percent of the patients received duplicate medications.

The researchers found that some of the drugs interacted with anticancer medications. The most common were warfarin (a drug to prevent blood clots), antihypertension drugs, aspirin and anticonvulsants. Warfarin stood out because it can cause hemorrhages when used with certain chemotherapy medications, and the interaction can interfere with its metabolism. Additionally, patients with brain tumors were at particularly high risk since they are often prescribed anticonvulsants.

"We suggest that patients at high risk… be routinely screened for potential drug interactions. The development of medication databases and computerize d physician medication order entry linked to screening electronic programs could help health professionals to identify dangerous drug combinations and monitor prescriptions of agents with high risks of interactions," the authors write.

In an accompanying editorial, Peter Norton, M.D., of the University of Calgary, and G. Ross Baker, Ph.D., of the University of Toronto, agree that a better system for tracking patients' medications is needed. "We believe that such coordination and communication have the potential to substantially reduce the incidence of and mitigate possible harm from the potential drug interactions that have been discovered by Riechelmann [and colleagues]. In other high-risk industries, such as aviation and the offshore oil industry, many errors result from poor coordination and communication, and in these areas, strategies to improve team coordination and communication have led to reductions in incidents," the authors write.

Source-Eurekalert
ME/V
'"/>




Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
(Date:10/13/2017)... ... ... Talented host, actor Rob Lowe, is introducing a segment ... of "Success Files," which is an award-winning educational program broadcasted on PBS Member ... with passion and integrity. , Sciatica occurs when the sciatic nerve in the ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
(Date:10/12/2017)... New Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... fitness centers in the U.S., announced today its plans to open a flagship location ... club will occupy the former Rooms To Go store next to Office Depot in ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... , Sept. 27, 2017  Commended for their devotion ... notable awards. Ranked as number one in the South Florida ... time in Inc. 5000 yearly list, the national specialty pharmacy ... Armando Bardisa will soon be honored by SFBJ ... Set to receive his award in ...
(Date:9/22/2017)... ROCKVILLE, Md. , Sept. 22, 2017  As ... by Republican Senators Bill Cassidy (R-LA) and ... Kalorama Information notes that the medical device industry is ... the medical device tax, the 2.3% excise tax on ... Act.  But they also want covered patients, increased visits ...
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
Breaking Medicine Technology: