Navigation Links
Cancer Experts Received Threats for Opposing Controversial Drug

Two prominent cancer experts receive e-mail and other forms of threats for opposing the drug Provenge meant for treating prostate cancer. Cancer survivors and advocates however, hold a demonstration on Saturday to urge the FDA to approve the drug. Controversy surrounding GlaxoSmithKline's diabetes drug Avandia also intensifies.

The persons responsible for sending the threats are yet to be identified. However, it is clear that the doctors public opposition to the drug, Provenge, has angered some patients with prostate cancer and their advocates, who insist the drug would provide relief to desperate patients with scarcely any alternatives. Approval of drugs, Last May, the Food and Drug Administration said that it would not approve Provenge without foolproof evidence that it was safe and effective.

Patients with incurable diseases, desperate for treatment, often advocate for approval new drugs, even if the research data supporting them are not fully encouraging. But it is the threats received by people with opposing views that makes the situation alarming. Drs. Scher and Hussain first publicly voiced dissenting views. But threats can discourage rational discussion of drugs and deter experts from serving on government advisory committees.

Provenge is now the latest focal point of a long-running and acrimonious debate about the quantum of evidence required for approval of drugs meant terminable diseases. Provenge was found to prolong lives in two small clinical trials, though the results were not sound by various statistical standards.

An F.D.A. advisory panel endorsed the effectiveness of the drug by a 13-4 vote during last March. The panel voted 17-0 that the drug was generally safe, although there were some signs it could increase the risk of strokes. Unlike most of the panel members, both Dr. Scher and Dr. Hussain, are actually the ones who treat patients with prostate cancer and they voted in the minori ty. They argued that the evidence fell short of proving that the drug was effective. They did not want to give patients false hope and wrote a letter to the F.D.A. reiterating their arguments.

About 15 prostate cancer survivors and advocates held a demonstration on Saturday to urge the agency to approve Provenge. Meantime, the controversy surrounding GlaxoSmithKline's diabetes drug Avandia intensified on Wednesday as a medical expert told Congress that executives threatened to sue him when he raised questions in 1999 about the treatment's safety.

"Despite additional warnings from outside experts, despite the millions of patients who rely on Avandia to control their blood sugar, and despite the potential risks involved, FDA never required the manufacturer to conduct a thorough post-market study of its heart risks," stated Rep. Henry Waxman, D-Calif, who chairs the House Committee on Oversight and Government Reform.

GlaxoSmithKline acknowledged the need for more studies, but described Avandia as safe. FDA Commissioner Andrew von Eschenbach said that FDA is ordering Glaxo and rival Eli Lilly to add black box warnings, about heart failure, to their diabetes drugs Avandia and Actos.


'"/>




Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2017)... ... August 23, 2017 , ... ... , has returned home to Indiana, and is now seeing patients at Boling ... ophthalmologist that specializes in the diagnosis and treatment of eye disease, medical retina, ...
(Date:8/23/2017)... ... August 23, 2017 , ... A ... of Orthopaedic Surgeons , points out that therapeutic modalities (physical therapy) is an ... According to the report, a wider scope of physical therapy options is showing ...
(Date:8/22/2017)... ... August 22, 2017 , ... Western North ... at a popular international aesthetics conference for medical professionals about the positive impact ... health and his growing practice. , Dr. George K. Ibrahim shared ...
(Date:8/22/2017)... ... August 22, 2017 , ... Five Star Glass is new to the Texas market, but ... of auto glass for most makes and models, in Grand Prairie, TX, located in the ... They have been a family owned business for the past 40 years with 32 convenient ...
(Date:8/22/2017)... (PRWEB) , ... August 22, 2017 , ... “Glimpses Of ... understanding of the world. “Glimpses Of Light” is the creation of published author, J.M. ... life in search of answers to life’s perplexing mysteries. , Shepherd shares, “Love is ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... MEMPHIS, Tenn. and BENTON, Ky. , Aug. 2, 2017 /PRNewswire/ ... new member to its environmental services (ES) team to proactively reduce the risk of hospital-acquired ... is a UV disinfection robot that uses UVC light energy to kill deadly pathogens such ... ... Tru-D ...
(Date:7/31/2017)... 31, 2017 Three Tru-D SmartUVC robots have arrived ... Korea . Tru-D, short for "Total Room Ultraviolet Disinfection," is a ... an environmental services (ES) professional cleans the area with traditional cleaning protocols. ... Tru-D fights germs ... "Although the BAACH has a very ...
(Date:7/27/2017)... Services, Inc. (NYSE: WST ) today announced ... financial guidance for the full-year 2017. ... Reported net sales of $397.6 million, a record high, ... constant currency (organic) grew by 3.9%. ... in the prior-year quarter. Second-quarter 2017 adjusted diluted EPS ...
Breaking Medicine Technology: