Navigation Links
Cancer Begins With Epigenetic Changes: Study

In a new study that is to appear in the January issue of Nature Reviews Genetics, a Johns Hopkins researcher suggests that cancers might begin with epigenetic //alterations instead of the traditional view that cancers usually occur in individuals whose genes have been altered by prevailing conditions. "We're not contradicting the view that genetic changes occur in the development of cancers, but there also are epigenetic changes and those come first," said lead author Andrew Feinberg, M.D., M.P.H., King Fahd Professor of Medicine and director of the Center for Epigenetics in Common Human Disease at Johns Hopkins.

His views are supported by fellow researchers in Sweden and at Fred Hutchinson Cancer Research Center. Professor Feinberg said that cells that have undergone epigenetic changes do not exhibit any alterations under the microscope, but subtle changes are detected at the level of the genome. Doctors can treat patients who are harboring these changes in much the same way as a cardiologist prescribes "cholesterol-lowering drugs to patients with fat deposits in their arteries," to prevent heart attacks. Epigenetic changes have been implicated in the development of cancer, birth defects and psychiatric conditions in previous studies. These changes include switching off the protection mechanisms that prevent the development of cancer. Cancers develop in three steps according to this study. The first step is where the epigenetic changes alter the balance in favor of the tumor-progenitor cells, secondly these cells trigger a mutation in the disturbed cells. As an example the altered sequence of chromosomes in chronic myeloid leukemia is mentioned. Finally, there is increased genetic and epigenetic instability leading to formation of the tumors. "Greater attention should be paid to the apparently normal cells of patients with cancer or those at risk for cancer, as they might be crucial targets for epigenetic alteration and might be an important target for pr
'"/>




Page: 1 2

Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Cancer Begins With Epigenetic Changes Study

(Date:7/31/2015)... ... ... Precision Aesthetics is New York’s only Thermage skin tightening pinnacle and black diamond award ... fat reduction in New York. Due to its unparalleled level of experience for ... patients travel to New York to get their non-surgical skin tightening and body shaping ...
(Date:7/31/2015)... ... July 31, 2015 , ... The 2nd annual Ride to ... Downtown Memphis on October 3, 2015. The Ride to Fight On is a cycling ... between Methodist Healthcare, The West Clinic and The University of Tennessee Health Science Center. ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... at its new True North Conference Center. The medical community, social workers, law ... community may be more aligned in the effort to better understand and combat ...
(Date:7/31/2015)... ... July 31, 2015 , ... M3 USA MDLinx.com, source ... launch three new Board Exam Courses. , The additions of Gastroenterology, Pulmonology and ... Prep from MDLinx makes preparing for the exam easy and painless. MDLinx offers ...
(Date:7/31/2015)... ... July 31, 2015 , ... According to an article published ... if they could reach a consensus on the steps that need to be taken ... group reached 90 percent consensus on a series of steps that each surgeon must ...
Breaking Medicine News(10 mins):Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 3Health News:MDLinx Offers Three New Board Exam Prep Courses - Gastroenterology, Pulmonology and Allergy/Immunology 2Health News:MDLinx Offers Three New Board Exam Prep Courses - Gastroenterology, Pulmonology and Allergy/Immunology 3Health News:Article on Plastic Surgery Consensus Highlights the Duties of Veteran Plastic Surgeons, says Beverly Hills Physicians 2Health News:Article on Plastic Surgery Consensus Highlights the Duties of Veteran Plastic Surgeons, says Beverly Hills Physicians 3
... Patricia Raymond offers tips on controlling your flatulence , ... ... is normal and necessary. In fact, the average person passes gas ... three liters daily). However, every body behaves differently and some experience ...
... program provides clients unparalleled live support services for http://www.appointment-plus.com ... ... Scottsdale, AZ (PRWEB) October 8, 2008 -- Appointment-Plus, the ... software client base by bucking trends. In a time ...
... today the extension of its existing strategic alliance with Nano-Terra, Inc., ... ... Germany (Business Wire EON) October 7, 2008 -- The original ... innovative, nanotechnology-based products and solutions based on Merck,s materials. , , ...
... IPRO, one of the,nation,s leading quality ... Liability Company (LLC) that will assume all ... with managed care,organizations (MCOs). The new entity, ... in New York State., (Logo: ...
... CHADD, the nation,s,largest organization serving people ... Annual,International Conference on AD/HD November 12-15 ... some of the leading experts speaking ... adults, clinicians, professionals, and,educators. To view ...
... Getting out of bed sooner helped quality of life after ... The best medicine for intensive care unit (ICU) patients may ... as they,re able, a new report says. , Based ... School of Medicine researchers concluded that the routine use of ...
Cached Medicine News:Health News:Managing Gas Isn't Rocket Science 2Health News:Managing Gas Isn't Rocket Science 3Health News:Appointment-Plus Continues Innovation With Technical Support Program 2Health News: Merck KGaA and Nano-Terra Announce Extension of Nanotechnology Solutions Alliance 2Health News: Merck KGaA and Nano-Terra Announce Extension of Nanotechnology Solutions Alliance 3Health News:IPRO Spins Off Managed Care Review Affiliate 2Health News:Early Mobility Best for ICU Patients 2
(Date:7/31/2015)... CHICAGO , July 31, 2015 ... Composition Analyzers Market by Product (Bioimpedance Analyzers (BIA), Dual-Energy ... and Hydrostatic Weighing) - Global Analysis & Forecast to ... Market was pegged at $911.1 Million 2014 and is ... at a CAGR of 9.4% from 2014 to 2019. ...
(Date:7/30/2015)... July 30, 2015  ResMed (NYSE: ... a definitive agreement to acquire Curative Medical, ... and sleep-disordered breathing medical devices and accessories. ... in China, combined with ResMed,s global leadership in sleep and respiratory ... China suffering from sleep-disordered ...
(Date:7/30/2015)... IRVINE, Calif. , July 30, 2015 /PRNewswire/ ... Novartis /Alcon executives have recently contacted the Company ... will begin as early as Monday, August 3, ... been quoted as saying that the coming electronic ... billions of dollars over the next several years.  ...
Breaking Medicine Technology:Body Composition Analyzers Market Worth $1,425.7 Million by 2019 2Body Composition Analyzers Market Worth $1,425.7 Million by 2019 3Body Composition Analyzers Market Worth $1,425.7 Million by 2019 4ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3
... Maine, July 14, 2011 IDEXX Laboratories, Inc. (Nasdaq: ... its 2011 second quarter financial results for Friday, July ... conduct an analyst conference call beginning at 9:00 a.m. ... Individuals can access a live Webcast of the ...
... Biomedical Corporation (OTCBB:QTXB), an emerging leader in the ... on its patented technology platforms for the worldwide ... the lawsuit with NURX, its prior Joint Venture ... operations to expand its over-the-counter products and laboratory ...
Cached Medicine Technology:QuantRx Biomedical Settles Suit: Launches New PAD-Based Genomic Diagnostic Products 2QuantRx Biomedical Settles Suit: Launches New PAD-Based Genomic Diagnostic Products 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: