Navigation Links
CT Scan Radiations may Lead to Cancer

An analysis based on computerized simulation models suggests that the lifetime risk of cancer associated with radiation exposure from a computed tomography (CT scan) coronary angiography varies widely, with the risk greater for women and younger patients.

Coronary artery disease (CAD) is the leading cause of death in men and women in the United States, accounting for 1 in 5 deaths, and a major cause of health care expenditures, with annual costs estimated at $142 billion, according to background information in the article.

Attempts to improve the diagnosis of this disease has led to the development of noninvasive methods for CAD diagnosis, including the 64-slice computed tomography coronary angiography (CTCA; combines multiple X-ray images with the aid of a computer to produce cross-sectional views of the heart and coronary arteries).

It has been predicted that CTCA may emerge as the diagnostic test of choice for patients with intermediate pretest probability of disease, yet there are little data on its associated cancer risk from exposure to radiation.

Andrew J. Einstein, M.D., Ph.D., of the Columbia University College of Physicians and Surgeons, New York, and colleagues conducted a study to estimate the lifetime attributable risk (LAR) of cancer incidence associated with radiation exposure from a 64-slice CTCA, and to determine how this risk is influenced by patient age, sex, and scan protocol.

The recent Biological Effects of Ionizing Radiation (BEIR) VII Phase 2 report provides a framework for estimating LAR of cancer incidence associated with radiation exposure from a CTCA by using a computational model and integrating the most current data available on health effects of radiation.

Lifetime cancer risk estimates for standard cardiac scans varied from 1 in 143 for a 20-year-old woman to 1 in 3,261 for an 80-year-old man. Use of simulated electrocardiographically controlled tube curre nt modulation (ECTCM; a dose reduction strategy that reduces radiation during part of the cardiac cycle) decreased these risk estimates to 1 in 219 and 1 in 5,017, respectively.

Estimated cancer risks using ECTCM for a 60-year-old woman and a 60-year-old man were 1 in 715 and 1 in 1,911, respectively.A combined scan of the heart and aorta had higher LARs, up to 1 in 114 for a 20-year-old woman. The highest organ LARs were for lung cancer and, in younger women, breast cancer.

In this study, we observed a marked variation by age, sex, and scan protocol for cancer risk associated with radiation exposure from CTCA, the authors write.

The results of this study suggest that CTCA should be used particularly cautiously in the evaluation of young individuals, especially women, for whom alternative diagnostic modalities that do not involve the use of ionizing radiation should be considered, such as stress electrocardiography, echocardiography, or magnetic resonance imaging.

If CTCA is considered as an alternative to invasive coronary angiography, the risks and benefits of each test require consideration.

Contact the JAMA/Archives Media Relations Department at 312-464-JAMA or email: mediarelations@jama-archives.org.


'"/>




Related medicine news :

1. Fibroids unlikely to Turn Cancerous
2. Virus Level could Predict Cervical Cancer Risk
3. Cancer Doctors Okays Controversial Prostate Therapy
4. Potential New Cancer Gene Identified
5. Consensus on "Combination Therapy" for Breast Cancer
6. Cancers of Colon & Rectum linked to Cigarette Smoking
7. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
8. The Cancer Rumour mill working over time
9. Cancer drugs in development nearly doubled since 1995
10. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
11. Cancer patients turning to Internet for information
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2017)... ... June 25, 2017 , ... An increase in wetter weather in the ... and along with that; a humdinger of an allergy season. A relief from drought ... increase in misery-causing grass and weed pollen. , “Our patients have been reporting ...
(Date:6/24/2017)... ... 24, 2017 , ... The Pennsylvania Athletic Trainers’ Society’s (PATS) ... Erie Convention Center on June 8-10. The weekend consisted of many educational ... and scholarship presentations, and professional networking. , On Friday June 9th, PATS ...
(Date:6/23/2017)... ... June 23, 2017 , ... "The Better ... ultimately do significant harm to people with all chronic conditions, including mental illnesses, ... leaves in place the Affordable Care Act (ACA) requirement that insurers cover pre-existing ...
(Date:6/23/2017)... ... June 23, 2017 , ... Dr. Ran Y. Rubinstein ... recently begun offering three new minimally invasive procedures to patients who want a ... downtime, Dr. Rubinstein is excited to bring microneedling, microneedling facials, and platelet rich ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... essential, and two new videos highlight the importance of correctly using a meat ... Ph.D., who has done extensive research on consumer food safety habits. Dr. Bruhn ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... 22, 2017  Lilac Corp, the company that ... launch of a new website . The ... a clinical study that showed surprising clearance of ... in individuals suffering from HPV warts, precancerous, or ... are no other treatments that clear the virus. ...
(Date:5/18/2017)... 2017  Two Bayer U.S. Pharmaceutical leaders received top ... recent 28 th Woman of the Year ... HBA,s longstanding mission of furthering the advancement and impact ... Cindy Powell-Steffen , senior director of brand activation ... Libby Howe , a regional business manager for ...
(Date:5/15/2017)... ATLANTA , May 15, 2017  Amy Baxter ... the industry leader in noninvasive pain relief, was awarded ... MM&M magazine. Baxter was recognized at the MM&M ... New York City on May 10, ... helping the biopharma industry go "beyond the pill."  ...
Breaking Medicine Technology: