Navigation Links
C -reactive Protein is the Marker for Cardiovascular Disease

According to a new study of children ages 5 to 7,C-reactive protein, a marker of inflammation that is often used to detect cardiovascular disease, may also indicate cognitive impairment in children with obstructive sleep apnea.

Children with OSA have increased levels of hsCRP [high-sensitivty C-reactive protein] and also exhibit decreased cognitive performances, said lead researcher David Gozal, M.D., of the University of Louisville in Kentucky. Furthermore, hsCRP levels are significantly increased among patients with OSA and cognitive dysfunction.

These findings were published in the second issue of the July American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

To identify children for the study, parents in the Jefferson County (KY) Public School system were invited to complete a questionnaire about their childrens sleeping habits. Responses indicating almost no likelihood of OSA and those indicating a high likelihood of OSA were randomly selected, and the children were invited to a sleep research center.

Obese children were excluded from the study, because the condition is now viewed as a low-grade systemic inflammatory disorder, and is associated with increased risk for cognitive deficits.

At the sleep center, the children underwent overnight polysomnographic assessment and then, in the morning, completed tests to determine their reasoning and conceptual abilities.

The results of the individual tests were aggregated into a General Conceptual Ability (GCA) score, with a mean of 100 and a standard deviation of 15 Of a total of 278 children who completed all phases of the evaluation, 73 served as controls. They had no evidence of OSA and their cognitive scores were all normal.

Among the 102 children with OSA, 57 had GCA scores less than 85 percent. The mean level of hsCRP in children with OSA and abnormal scores was approximatel y 250 percent higher than the control group and approximately 200 percent higher than the level for children with OSA who did not exhibit cognitive impairment.

The authors suggest that an important question yet to be answered is whether OSA treatment would eliminate any cognitive deficits. They cite an earlier study they conducted which found that after an adenotonsillectomy, hsCRP levels in children with OSA were usually reduced.

According to the authors, however, the current findings reinforce the concept that systemic inflammation is a constitutive component and consequence of OSA and that the presence of increased systemic inflammation, as dictated by hsCRP levels and potentially the levels of other inflammatory markers, will increase the probability for decreased neurocognitive function.


'"/>




Related medicine news :

1. Artery Stiffness Linked To Increasing Levels Of C-reactive protein
2. C-reactive Protein (CRP) Levels Could Assess Future Lung Cancer Risk In Smokers
3. Lean Protein Could Be Key to Obesity Drugs
4. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
5. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
6. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
7. Protein in urine foresees heart disease
8. Levels Of Blood Proteins May Help Heart Disease Care
9. Protein signals need for heart surgery
10. Protein and fat improve memory
11. Clotting Protein plays a role in nerve repair
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/19/2017)... Aliso Viejo, California (PRWEB) , ... January 19, ... ... self animating paragraph styled text designs that will simplify the editing process for ... , ProParagraph Basics is a package of 30 simplistically styled self-animating paragraphs ...
(Date:1/19/2017)... ... January 19, 2017 , ... Fillers are known for building ... know that popular cosmetic fillers can enhance earlobes and rejuvenate an ... of the MilfordMD Cosmetic Dermatology Surgery & Laser Center, in Milford, Penn. “People ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... the number one doctor-recommended OTC antiperspirant, Certain Dri. , Excessive sweating and hyperhidrosis ... Certain Dri created this infographic to explain the seven types of hyperhidrosis. This ...
(Date:1/18/2017)... ... ... The V Foundation for Cancer Research, a top-rated cancer research charity, announced ... to compete in the Boston Marathon on April 17. From first-time participants to ... marathon to join Team V and support the Foundation’s mission to declare victory over ...
(Date:1/18/2017)... ... January 18, 2017 , ... Park Agencies Insurance & Financial ... families and business owners in the greater Kansas City area, is joining the ... , The Lakemary Center is a comprehensive educational resource center that provides area ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , January 19, 2017 According to ... for cryotherapy is set to witness a CAGR of 6.5% during ... America will continue to be the leading market for ... ... Suppliers are emphasizing on ensuring affordable and adequate supply of gas ...
(Date:1/19/2017)... 2017 Accuray Incorporated (Nasdaq: ARAY ... continue to set the bar for excellence in customer ... user satisfaction rating among radiation treatment delivery systems in ... Market Intelligence Briefing™. The most recent ratings trend also ... industry peers for 11 of the past 12 quarters. ...
(Date:1/19/2017)... Calif. , Jan. 19, 2017  Abaxis, Inc. ... manufacturing point-of-care blood analysis instruments and consumables for the ... call to discuss its financial results for the third ... call will be at 4:15 p.m. ET on Thursday, ... for the third quarter fiscal year 2017 after the ...
Breaking Medicine Technology: