Navigation Links
Buckyball Has the Ability to Fight Against Allergy: Research

A new biological function for a soccer ball-shaped nano-particle called buckyball has been identified.

A research team has found that buckyball has the ability to block allergic reaction, making the progress of new therapies for allergy possible.

Allergic disease is the sixth leading cause of chronic disease in the United States, and though various treatments have been developed to control allergy, no cure has been found. These findings advance the up-and-coming field of medicine known as nanoimmunology.

The researchers, from Virginia Commonwealth University and Luna Innovations Inc., a private, Roanoke, Va., research company, are the first to demonstrate that buckyballs are able to block allergic response in human cell culture experiments.

Buckyballs, or fullerenes, are nanoparticles containing 60 carbon atoms. Owing to their exclusive structure, unresponsiveness and steadiness, researchers from a number of scientific fields have been investigating the tiny, hollow carbon cages to serve a variety of functions.

In this study, researchers modified the buckyballs so that they were attuned to water.

"This discovery is exciting because it points to the possibility that these novel materials can one day lead to new therapies," said Chris Kepley, Ph.D., M.B.A., assistant professor in the Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology at the VCU School of Medicine.

"Researchers in many fields are aware of the potential fullerenes have, however, we are the first to show they can turn off the allergic response and basic immune reactions," he said.

According to Kepley, who is the main author of the paper, the buckyballs are able to 'interrupt' the allergy/immune response by holding back a crucial process in the cell that leads to the discharge of an allergic mediator. Fundamentally, the buckyballs are able to prevent mast cells from r eleasing histamine.

Mast cells are responsible for causing allergic response and are packed with granules containing histamine. They are present in nearly all tissues barring blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are quickly released into the tissues and blood, promoting an allergic response.

The researchers found that the unique structure of the buckyball allows it to attach to free radicals noticeably better than any anti-oxidant currently available, such as vitamin E. Free radicals are molecules that cause oxidative stress, which experts believe may be the basis of aging.

"The immune system both protects us and causes harm, so we are always interested in finding new pathways to help manage the harmful effects," said Kepley.

The new study findings were published online in the Journal of Immunology.


'"/>




Related medicine news :

1. Buckyballs Used as Passkey into Cancer Cells
2. Soya Found To Affect Womens Ability To Conceive: Professor
3. Humans Found To Have The Ability To Block Unwanted Memories
4. Watching Violent, Churning Movie Scenes Affect Problem-Solving Ability
5. Telomerase Vital In Maintaining Ability of Stem Cell to Multiply
6. Marijuana Causes The Brain To Lose Its Ability
7. As You Age Check Your BP for It Can Affect Your Mental Ability
8. Cocoa Has The Ability To Improve Blood Circulation
9. A Womans Sporting Ability Is In Her Fingers!
10. Fitness and Childhood IQ Indicators of Cognitive Ability in Old Age
11. Common Virus Enhances Cancer-Fighting Ability of Standard Chemotherapy Drugs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... Viejo, California (PRWEB) , ... June 25, 2016 , ... ... to fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... fully customizable and all within Final Cut Pro X . Simply select a ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
Breaking Medicine Technology: