Navigation Links
Buckyball Has the Ability to Fight Against Allergy: Research

A new biological function for a soccer ball-shaped nano-particle called buckyball has been identified.

A research team has found that buckyball has the ability to block allergic reaction, making the progress of new therapies for allergy possible.

Allergic disease is the sixth leading cause of chronic disease in the United States, and though various treatments have been developed to control allergy, no cure has been found. These findings advance the up-and-coming field of medicine known as nanoimmunology.

The researchers, from Virginia Commonwealth University and Luna Innovations Inc., a private, Roanoke, Va., research company, are the first to demonstrate that buckyballs are able to block allergic response in human cell culture experiments.

Buckyballs, or fullerenes, are nanoparticles containing 60 carbon atoms. Owing to their exclusive structure, unresponsiveness and steadiness, researchers from a number of scientific fields have been investigating the tiny, hollow carbon cages to serve a variety of functions.

In this study, researchers modified the buckyballs so that they were attuned to water.

"This discovery is exciting because it points to the possibility that these novel materials can one day lead to new therapies," said Chris Kepley, Ph.D., M.B.A., assistant professor in the Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology at the VCU School of Medicine.

"Researchers in many fields are aware of the potential fullerenes have, however, we are the first to show they can turn off the allergic response and basic immune reactions," he said.

According to Kepley, who is the main author of the paper, the buckyballs are able to 'interrupt' the allergy/immune response by holding back a crucial process in the cell that leads to the discharge of an allergic mediator. Fundamentally, the buckyballs are able to prevent mast cells from r eleasing histamine.

Mast cells are responsible for causing allergic response and are packed with granules containing histamine. They are present in nearly all tissues barring blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are quickly released into the tissues and blood, promoting an allergic response.

The researchers found that the unique structure of the buckyball allows it to attach to free radicals noticeably better than any anti-oxidant currently available, such as vitamin E. Free radicals are molecules that cause oxidative stress, which experts believe may be the basis of aging.

"The immune system both protects us and causes harm, so we are always interested in finding new pathways to help manage the harmful effects," said Kepley.

The new study findings were published online in the Journal of Immunology.


'"/>




Related medicine news :

1. Buckyballs Used as Passkey into Cancer Cells
2. Soya Found To Affect Womens Ability To Conceive: Professor
3. Humans Found To Have The Ability To Block Unwanted Memories
4. Watching Violent, Churning Movie Scenes Affect Problem-Solving Ability
5. Telomerase Vital In Maintaining Ability of Stem Cell to Multiply
6. Marijuana Causes The Brain To Lose Its Ability
7. As You Age Check Your BP for It Can Affect Your Mental Ability
8. Cocoa Has The Ability To Improve Blood Circulation
9. A Womans Sporting Ability Is In Her Fingers!
10. Fitness and Childhood IQ Indicators of Cognitive Ability in Old Age
11. Common Virus Enhances Cancer-Fighting Ability of Standard Chemotherapy Drugs
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... Las Vegas, Nevada (PRWEB) , ... February 08, ... ... Co-Founder at RowdMap, Inc., will be speaking on how healthcare companies can use ... project costs, manage the health of a population and intervene and capture the ...
(Date:2/7/2016)... ... 07, 2016 , ... Women's Excellence staff, in all four locations, wore red ... Red Day is the first Friday each February and a day to bring attention ... 3 deaths among women each year – more than all cancers combined. Go Red ...
(Date:2/6/2016)... ... February 06, 2016 , ... With the FCPX ... warm color grades to their footage. A LUT is a Lookup Table that contains ... the corresponding color indicated by the table. By manipulating each pixel, LUT's can change ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... the company's lighter, sleeker next generation LYNX VR Indoor Trainer with multi-rider capability ... in design and manufacturing not only reduce the weight of the unit, they ...
(Date:2/5/2016)... Rosa, CA (PRWEB) , ... February 05, 2016 ... ... pleased to announce the addition of micro-needling services in their Napa Valley office. ... The founders of Plastic Surgery Associates, Dr. Canales and Dr. Furnas, are part ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... --> --> ... the global active pharmaceuticals ingredients (APIs) market stood at ... US$185.9 bn by 2020. It is expected to expand ... The title of the report is "Active Pharmaceutical Ingredients ... by Therapeutic Area) - Global Industry Analysis, Size, Share, ...
(Date:2/5/2016)... WARSAW, Ind. , Feb. 5, 2016  Zimmer ... the pricing of the previously announced underwritten secondary offering ... of its stockholders, consisting of affiliates of Blackstone and ... public at an initial price of $96.45 per share. ... of the offering.  Neither Zimmer Biomet nor any of ...
(Date:2/5/2016)... 5, 2016  Henry Schein, Inc. (NASDAQ: HSIC ), ... services to office-based dental, animal health and medical practitioners, ... to acquire a majority ownership interest in Dental Cremer ... Brazil . ... Cremer is the dental distribution business of Cremer S.A. ...
Breaking Medicine Technology: