Navigation Links
Bubble Technique on the cards For Treatment of Type I diabetes

Researchers at Baylor University Medical Center at Dallas and the Baylor Research Institute have developed a new way to introduce insulin genes into the pancreas//.

Insulin is a hormone that allows blood glucose (blood sugar) to enter the cells of the body to be used for energy. The technique, known as ultrasound-targeted micro bubble destruction (UTMD), delivers these insulin genes to the organ via microscopic "bubbles." Once the bubbles reach their target, they are burst with ultrasound releasing the insulin genes into the pancreas.

Using UTMD, researchers delivered the bubbles containing human insulin genes into the pancreas of rats and later found that the rat's blood sugar had been subsequently lowered. Another gene that regulates insulin production, known as hexokinase I, was successfully delivered using UTMD as well, and resulted in increased blood insulin and decreased blood sugar in the rats.

"Not only was their blood sugar lowered, but there was no evidence of any damage to the pancreas," says Paul Grayburn, M.D., principal investigator of the study. "Other forms of gene therapy are usually invasive and unlike the UTMD technique, do not target the tissues and organs specifically."

Currently, patients with Type I (juvenile onset) diabetes must inject themselves with insulin daily to keep their blood sugar levels balanced in addition to following strict nutritional guidelines. Dr. Grayburn says that the UTMD technique is one of the most important steps in the development of a successful treatment of diabetes without the need for daily insulin injections.

"Now that we have successfully delivered insulin genes to the pancreas, our ultimate goal is to research the regeneration of insulin-producing cells in patients with diabetes," says Dr. Grayburn.

In the future, Dr. Grayburn says that the UTMD technique for gene delivery can be used to deliver therapeutic agents to other organs as w ell.

Nationwide, more than one million people have Type 1 (juvenile onset) diabetes. Diabetes – the fifth deadliest disease in the United States – affects the body's ability to produce or respond to insulin. People with Type I diabetes are at increased risk for many serious complications, including heart disease, blindness, nerve damage and kidney damage.

Source : Eureka Alert
'"/>




Related medicine news :

1. Gene Therapy For Bubble Baby Syndrome May Lead To Blood Cancer
2. Bubble Boy Gene Therapy Causes Cancer?
3. Bubble-Blowing Infants may Learn Language Skills Faster
4. Researchers Use Bubbles in Cancer Treatment and Drug Delivery
5. Discovery In "Bubble Boy" Disease Gene Therapy
6. New Laser Techniques cure degeneration of the eye
7. New Technique to Study Infants Brain.
8. New Technique For Benign Breast Tumors
9. Preventing Strokes Using Less Invasive Techniques
10. New Technique To Detect Activity Of Drugs In The Body
11. New Technique To Test Stem Cells That Heal The Heart
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2017)... ... June 28, 2017 , ... Anyone with a remote control has seen the never-ending twists on ... the flipper will get rich in no time. But what about the buyers of ... for the buyer of a flipped house. An email recently sent to Gary Case ...
(Date:6/28/2017)... , ... June 28, 2017 , ... David B. Sosin, a founding partner ... took over the post of 2nd Vice President for the Illinois State Bar Association ... as the ISBA’s 3rd Vice President in 2016 following a state-wide election and served in ...
(Date:6/28/2017)... ... June 28, 2017 , ... American Farmer proudly announces ... of the award winning television series, scheduled to broadcast fourth quarter 2017. American Farmer ... as a regional supplier of garden pea seed. As demand grew, the small company ...
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... ZEON) is pleased to announce that a two year study conducted by the ... Bromley Creek zeolite was successful in remediating potash brine-impacted groundwater. As a part ...
(Date:6/28/2017)... ... June 28, 2017 , ... Doner Financial, a Cincinnati ... to insurance assistance and financial planning services, is announcing the commencement of a ... the region facing financial crisis. , Matthew 25: Ministries (M25M) is an international ...
Breaking Medicine News(10 mins):
(Date:6/11/2017)...  Eli Lilly and Company (NYSE: LLY ) ... of galcanezumab, an investigational treatment for the prevention of ... key secondary endpoints for galcanezumab compared to placebo at ... EVOLVE-2 and REGAIN) will be presented today at the ... Boston . "The detailed ...
(Date:6/8/2017)... Fla. , June 8, 2017  Less than ... that hit more than 200,000 companies, including hospital networks, ... being heralded as one of the largest online extortion ... in the healthcare market, it is imperative that providers ... protect their data from this — and many other ...
(Date:6/7/2017)... Inc., (Nasdaq: NVAX ) today announced that data ... RSV F protein recombinant nanoparticle vaccine candidate (RSV F Vaccine) ... the journal Vaccine (the data contained ... The Company previously announced top line results from ... F Vaccine with the goal of protecting infants from RSV ...
Breaking Medicine Technology: