Navigation Links
Breast feeding can prevent HIV infection transmission

William Paxton and Colleagues from University of Amsterdam has found that Breast feeding milk helps to prevent transmission of HIV infection to child. Though it is well// known that Mother to child transmission of HIV accounts for a large proportion of HIV infections in children, with many infected as a result of breastfeeding, which requires transfer of the virus across mucosal barriers. These researchers have found a mechanism by which human milk affects the HIV interactions with DC-SIGN that occurs during breast feeding. The results of the research will be published in Journal of Clinical Investigation.

The authors show that human milk can block the binding of HIV to the DC-SIGN (DC-SIGN, a DC lectin receptor, interacts with HIV and is found at high expression levels in tonsillar tissue), molecule expressed on dendritic cells and potently inhibit the transfer of HIV-1 to CD4+ T-lymphocytes. The researchers have found a compound in human milk which binds to DC-SIGN and found to have an inhibitory effect by fully alleviated with an antibody recognizing the Lewis X sugar epitope on this factor. Other major milk proteins do not bind to DC-SIGN nor inhibit viral transfer. These results demonstrate that protein associated Lewis X is necessary and sufficient to interact with DC-SIGN and block the interaction of DC-SIGN and HIV.

The identification of a factor in human milk that can block HIV-1 transmission, the ability of the factor to inhibit the virus from binding to DCs, and the potential immunomodulatory implications of such a compound has major implications for the development of agents that can block HIV transmission.

Information on Breast feeding in Medindia:

Feeding her baby is a lifetime experience for a woman and there is no substitute for the mother's milk to the child. This is one of the most beautiful periods in the life for both the mother and child where the bond for each other develops. Breast feeding not only develops a baby into a healthy human being, but also contributes greatly to the mental development. In this feature, an attempt is made to make the expectant mother understand the various aspects of breast-feeding and its importance.
'"/>




Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing ... which patients and their families pay tribute to a genetic counselor by nominating him ... Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s ... the world, and the most handsome men, look naturally attractive. Plastic surgery should ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)...  In a startling report released today, National Safety Council ... a comprehensive, proven plan to eliminate prescription opioid overdoses. ... states are tackling the worst drug crisis in recorded U.S. history, ... Kentucky , New Mexico , ... the 28 failing states, three – Michigan , ...
(Date:6/23/2016)... Bracket , a leading clinical trial technology and specialty ... Bracket eCOA (SM) 6.0, at the 52 nd ... in Philadelphia , Pennsylvania.  A demonstration of ... its kind to fully integrate with RTSM, will be held ... a flexible platform for electronic clinical outcomes assessments that is ...
Breaking Medicine Technology: