Navigation Links
Breast feeding can prevent HIV infection transmission

William Paxton and Colleagues from University of Amsterdam has found that Breast feeding milk helps to prevent transmission of HIV infection to child. Though it is well// known that Mother to child transmission of HIV accounts for a large proportion of HIV infections in children, with many infected as a result of breastfeeding, which requires transfer of the virus across mucosal barriers. These researchers have found a mechanism by which human milk affects the HIV interactions with DC-SIGN that occurs during breast feeding. The results of the research will be published in Journal of Clinical Investigation.

The authors show that human milk can block the binding of HIV to the DC-SIGN (DC-SIGN, a DC lectin receptor, interacts with HIV and is found at high expression levels in tonsillar tissue), molecule expressed on dendritic cells and potently inhibit the transfer of HIV-1 to CD4+ T-lymphocytes. The researchers have found a compound in human milk which binds to DC-SIGN and found to have an inhibitory effect by fully alleviated with an antibody recognizing the Lewis X sugar epitope on this factor. Other major milk proteins do not bind to DC-SIGN nor inhibit viral transfer. These results demonstrate that protein associated Lewis X is necessary and sufficient to interact with DC-SIGN and block the interaction of DC-SIGN and HIV.

The identification of a factor in human milk that can block HIV-1 transmission, the ability of the factor to inhibit the virus from binding to DCs, and the potential immunomodulatory implications of such a compound has major implications for the development of agents that can block HIV transmission.

Information on Breast feeding in Medindia:

Feeding her baby is a lifetime experience for a woman and there is no substitute for the mother's milk to the child. This is one of the most beautiful periods in the life for both the mother and child where the bond for each other develops. Breast feeding not only develops a baby into a healthy human being, but also contributes greatly to the mental development. In this feature, an attempt is made to make the expectant mother understand the various aspects of breast-feeding and its importance.

Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:

(Date:11/24/2015)... Port Richey, FL (PRWEB) , ... November 24, 2015 , ... ... it deems a growing epidemic as deaths from prescription opioids in the United States ... heroin and cocaine. In 2013 alone, opioids were involved in 37 percent of all ...
(Date:11/24/2015)... ... November 24, 2015 , ... Serenity Point Rehabilitation, a holistic treatment ... video interviews with some of the staff members at their recovery center. The videos ... as well as some of the things that make their recovery program so unique. ...
(Date:11/24/2015)... PALMYRA, Wis (PRWEB) , ... November 24, 2015 ... ... Process scholarship award at Cleveland University-Kansas City (CU-KC), in Overland Park, ... scholarship from Chiropractor and University President Carl S. Cleveland III on October 16. ...
(Date:11/24/2015)... N.Y. (PRWEB) , ... November 24, 2015 , ... Autism ... Tuesday, the global movement driven by social media and the generosity of people around ... then encourage their social media networks to give – and share the personal stories ...
(Date:11/24/2015)... , ... November 24, 2015 , ... ... of patented products, announces Fragrance by Marcelle, a cosmetic invention which offers a ... & Fragrance Manufacturing Market in the US is worth $3 billion annually," says ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... 24, 2015 Avery Biomedical Devices (ABD), manufacturer ... announce the appointment of Anders Jonzon , MD; ... Dr. Jonzon is a Physiologist ... Hospital, Uppsala University, Uppsala and Children,s Hospital, Karolinska, ... a fellow at the Cardiovascular Institute (UCSF). His research ...
(Date:11/24/2015)... 24, 2015  Ascendant Solutions, Inc. (Pink Sheets: ASDS ... of Directors has declared a special 1 percent stock dividend ... payable December 14, 2015, to shareholders of record December 7, ... additional shares of common stock. --> ... a strong endorsement of our confidence in Ascendant,s growth strategy ...
(Date:11/24/2015)... st  Scientific Assembly and Annual Meeting of the Radiological Society ... Chicago on Nov-29 th through Dec-4 ...  Scientific Assembly and Annual Meeting of the Radiological Society of ... Chicago on Nov-29 th through Dec-4 th , ... present its revolutionary whole body CZT digital SPECT/CT solution at the ...
Breaking Medicine Technology: