Navigation Links
Breast Tumor Metastasis Stimulated by Post Pregnancy Circumstances

Breast Tumor Cells may develop due to changes in the tissue environment of the breast that occur after pregnancy, according to a paper by McDaniel. This study has found a place in the February issue of The American Journal of Pathology. //

The stages of pregnancy, lactation, and involution dictate drastic changes in the tissues of the human breast, resulting in multiplication, differentiation and death of mammary cells. This happens due to the alteration in the environment surrounding the cells, technically termed as the extra cellular matrix. The findings suggest an epidemiological link between breast cancer after pregnancy and inadequate diagnosis.

Dr. Pepper Schedin led a team of researchers at the University of Colorado Health Science Center, which compared the extracellular matrix from mammary glands of rats in the stage of post-lactation involution to that of virgin rats. The study revealed that the involution matrix comprised greater levels of matrix proteases and degraded proteins and generally more matrix proteins than virgin matrix, suggesting that the involution matrix was experiencing significant changes in its structure. Differences in the source of the matrix popped up when “normal” human breast cells were grown on each matrix.

This sought to establish that human breast tumor cells migrated in a better fashion through the involution matrix rather than through the virgin matrix. The group thereafter conducted in vivo studies to confirm the hypothesis that post-lactation involution matrix promotes tumor cell migration, called metastasis..

The alterations in the extra cellular matrix that take place post-pregnancy involution may actually bring about metastasis of breast cancer following pregnancy. This study indicates the progress made in studying specific gene mutations to studying the tumor environment, intensifying and gaining added focus in recent years.


'"/>




Page: 1

Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... September 22, 2017 , ... First Choice Emergency Room ... one year anniversary of its Houston-Fallbrook facility. , “We are honored to ... Director of First Choice Emergency Room Houston-Fallbrook. “It has been a pleasure serving ...
(Date:9/22/2017)... ... September 22, 2017 , ... “Fruit of the Spirit: “Love””: a ... that God has created. “Fruit of the Spirit: “Love”” is the creation of published ... wife and mother of five. Halimah is an avid writer, her inspiration for “Fruit ...
(Date:9/22/2017)... ... September 22, 2017 , ... ... and create life. Although frozen embryos have a slight statistical advantage for live ... freezing is a wonderful opportunity for women undergoing medical treatment or who are ...
(Date:9/21/2017)... Naples, FL (PRWEB) , ... September 21, 2017 , ... ... , Aesthetic Surgery Center in Naples, Florida is pleased to announce that Plastic Surgeon ... Business Top 40 Under 40 is an annual award that was started ...
(Date:9/21/2017)... ... September 21, 2017 , ... The American ... Health Services for professionals in the addiction treatment industry entitled: Special Investigations ... , Insurance companies and state and federal governments are increasingly scrutinizing the addiction ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... 2017 Caris Life Sciences, a leading ... promise of precision medicine, today announced results from ... its molecular profiling approach in guiding therapeutic strategies ... plus (CGP+) with Caris Molecular Intelligence ® ... molecular level, leading to more therapeutic options and ...
(Date:9/7/2017)... BOTHELL, Wash. , Sept. 7, 2017   BioLife ... developer, manufacturer and marketer of proprietary clinical grade cell and ... media ("BioLife"), announces that Mike Rice , President and ... Rodman & Renshaw 19 th ... 3:25 p.m. Eastern time (12:25 p.m. Pacific time). The conference ...
(Date:9/6/2017)... N.Y. , Sept. 6, 2017   PDI , ... announced it will host an educational session focused on ... bloodstream infection (CLABSI) prevention at the 2017 Annual Scientific ... which will take place at the Phoenix ... from Sept. 16-19, will also feature PDI,s ...
Breaking Medicine Technology: