Navigation Links
Breast Tumor Metastasis Stimulated by Post Pregnancy Circumstances

Breast Tumor Cells may develop due to changes in the tissue environment of the breast that occur after pregnancy, according to a paper by McDaniel. This study has found a place in the February issue of The American Journal of Pathology. //

The stages of pregnancy, lactation, and involution dictate drastic changes in the tissues of the human breast, resulting in multiplication, differentiation and death of mammary cells. This happens due to the alteration in the environment surrounding the cells, technically termed as the extra cellular matrix. The findings suggest an epidemiological link between breast cancer after pregnancy and inadequate diagnosis.

Dr. Pepper Schedin led a team of researchers at the University of Colorado Health Science Center, which compared the extracellular matrix from mammary glands of rats in the stage of post-lactation involution to that of virgin rats. The study revealed that the involution matrix comprised greater levels of matrix proteases and degraded proteins and generally more matrix proteins than virgin matrix, suggesting that the involution matrix was experiencing significant changes in its structure. Differences in the source of the matrix popped up when “normal” human breast cells were grown on each matrix.

This sought to establish that human breast tumor cells migrated in a better fashion through the involution matrix rather than through the virgin matrix. The group thereafter conducted in vivo studies to confirm the hypothesis that post-lactation involution matrix promotes tumor cell migration, called metastasis..

The alterations in the extra cellular matrix that take place post-pregnancy involution may actually bring about metastasis of breast cancer following pregnancy. This study indicates the progress made in studying specific gene mutations to studying the tumor environment, intensifying and gaining added focus in recent years.


'"/>




Page: 1

Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... ... July 20, 2017 , ... Using CDRH’s Medical Device ... — 1:30 p.m. – 3:00 p.m. ET, http://www.fdanews.com/mdqualitydata          , Device makers ... It’s known as the “CY2016 Annual FDA Medical Device Quality System Data” report. ...
(Date:7/20/2017)... ... July 20, 2017 , ... The ... Architecture Body of Knowledge (BIZBOK® Guide )v 6.0 is now available for member ... effort through Guild collaborative teams. , Non-members may download the Part 1 ...
(Date:7/20/2017)... ... July 19, 2017 , ... A local ... and increased funds raised to support fine arts programs in Chester County’s Elementary ... in Freed-Hardeman University’s Loyd Auditorium. , More than 850 people attended the ...
(Date:7/20/2017)... , ... July 19, 2017 , ... ... $1.5 million Health Resources and Services Administration (HRSA) grant to train predoctoral dental ... health care needs in rural and underserved areas. , The Predoctoral Pediatric Training ...
(Date:7/20/2017)... ... July 20, 2017 , ... “Fidget”: a fun-filled, action-packed memoir of adventures. ... school music and drama teacher who was a summa cum laude graduate of Gardner ... of the Year” award. After her retirement from public school, Lynn continued to pursue ...
Breaking Medicine News(10 mins):
(Date:7/15/2017)... 15, 2017 Enterin Inc., a Philadelphia ... disease (PD), today announced the completion of a $12.7 million ... Ventures III, as well as the participation of existing investors. ... to have the support of New Ventures III and our ... validation of the potential of our platform technology to transform ...
(Date:7/13/2017)... WILLIAMSTON, Mich. , July 13, 2017  Centurion Medical Products, ... offers its DisImpactor ® fecal impaction removal device for hospice ... ... Patient pain management ... DisImpactor for Hospice can help alleviate patient pain while preventing unneeded ...
(Date:7/12/2017)... is a revolutionary new product that relieves painful carpal tunnel syndrome ... affects more than 8 million people a year. Women suffer from ... methods of treating CTS are painful surgery, the use of NSAIDs ... ... a clear patch worn on the palm of the hand. It ...
Breaking Medicine Technology: