Navigation Links
Breast Cancer Mortality Rate is Higher Among Black Women

cology division at UNC’s School of Medicine, modern technologies such as microarray analysis can reveal the molecular characteristics of cancers and have shown that breast cancer is not one disease. 'It is a family of diseases that are biologically different from each other, some more aggressive than others,' Carey said. 'In this study, using the Carolina Breast Cancer Study, we were looking at how frequently these different subtypes occur in a given population.'

DNA microarray analysis allows scientists to determine the expression levels of thousands of genes simultaneously. This can reveal gene expression patterns, which, in turn, enable genomic profiling of tumor cells.

UNC School of Medicine study co-author Dr. Charles M. Perou, assistant professor of genetics, pathology & laboratory medicine, and a Lineberger member, is a pioneer in microarray technology. 'Gene expression analysis using DNA microarrays has identified several breast cancer subtypes, including luminal A, luminal B, basal-like and HER2-plus/estrogen receptor-negative,' said Perou. 'These studies were based on limited sample sets. We wanted to see if we could identify the presence of these subtypes through a population-based study and to find out if they correlate with factors such as age, menopausal status and race.'

But microarray analysis requires freshly frozen tumor tissue specimens, and the tissue available from the CBCS was collected between 1993 and 2001. Fortunately, the CBCS had many tumor tissue samples in blocks of paraffin.

The test involves immunohistochemistry (IHC) profiling, which is the testing of sections of tissue for specific proteins by attaching them to specific antibodies, and then looking for the antibodies through the enzymes to which they were connected. This IHC test was refined for the JAMA study, which was the first time the IHC method was used to examine breast cancer subtypes in a population-based study.

'An
'"/>




Page: 1 2 3

Related medicine news :

1. Consensus on "Combination Therapy" for Breast Cancer
2. Breast cancer treatment to be determined by gene test
3. Breast Feeding prevents obesity later on in life
4. Breast milk is essential
5. Breast Cancer Surgery Causes Psychological problems
6. Breast cancer evidence
7. Letrozole Beats Tamoxifen in Breast Cancer Therapy
8. Breast screening among diabetic women
9. Breast feeding can alter hormones
10. Diet, Sunlight connected to Breast Cancer Risk
11. Additional Radiotheraphy for Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Breast Cancer Mortality Rate Higher Among Black Women

(Date:8/28/2014)... 2014 In the healthcare industry, there ... struggle with: How can the overall quality of patient ... of the healthcare industry tackles this question, and has ... job satisfaction and the quality of patient care. ... in “ Organizational Factors related to Improving Quality of ...
(Date:8/28/2014)... August 28, 2014 Tea Leaves ... with Gigya, the leader in Connected Consumer Management. ... Leaves will have the opportunity to build more ... who they are and how they like to ... the world’s biggest brands to understand and connect ...
(Date:8/28/2014)... Livermore, CA (PRWEB) August 28, 2014 ... newest California physician, James Patel M.D. of Livermore, California. ... the best and most qualified physicians, and in accordance ... and our patients to Dr. Patel’s practice. , Initially ... at a young age, Dr. Patel was shaped by ...
(Date:8/28/2014)... 2014 The need for larger space has ... few years. The new location - 4700 Bryant Irvin Court, ... larger office space than TLC had in the past, as ... pleased about our new location because it represents a good ... be double in size compared to the current one, the ...
(Date:8/27/2014)... August 28, 2014 Author and orthopedic ... takes readers on the thrilling adventures of sharp and ... in 2012, is gearing up for a new marketing ... into two novellas , “Prescription: Murder” follows the ... finds himself dodging assassination attempts and thwarting criminals. In ...
Breaking Medicine News(10 mins):Health News:New Healthcare Study Explores Strategies for Improving Patient Care 2Health News:New Healthcare Study Explores Strategies for Improving Patient Care 3Health News:New Healthcare Study Explores Strategies for Improving Patient Care 4Health News:Tea Leaves Health Begins Important New Partnership with Gigya 2Health News:Tea Leaves Health Begins Important New Partnership with Gigya 3Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 3Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 4Health News:William H. Simon Launches New Marketing Campaign for Book 2
... the US, WAYNE, N.J., May 20 Maureen McCormick, ... sitcom, The Brady Bunch, is the new,celebrity ambassador for the ... by storm and is now available in the,United States., ... lost over 30,lbs. and was announced winner of the fifth ...
... certification ... Enterprise software, PARSIPPANY, N.J., May 20 Satyam Computer,Services ... information,technology services provider, and GE Healthcare, today announced a,comprehensive agreement ... Enterprise software., The companies will join forces to plan, ...
... in Nature Nanotechnology suggests some forms of carbon nanotubes ... be as harmful as asbestos if inhaled in sufficient quantities. ... types of nanotubes have the potential to cause mesothelioma ... years to appear following exposure. The results show that ...
... Intensive therapy did not improve recovery or survival, researchers ... Intensive kidney dialysis for patients with acute kidney injury ... the rate of organ failure, a new study finds. ... in critically ill patients. Approximately 2 percent to 7 ...
... Improving, Animal Health and Well-Being; Co-sponsored by Hill,s Pet ... FANCY, CAT FANCY and Veterinary Practice News Magazines, ... veterinarian is the,best in America, nominate him or her ... Pet(SM) Contest. The national short-essay contest honors,America,s veterinarians for ...
... TSP-1 expression has been found to correlate with the ... rat livers with high vascular densityin other words, angiogenesis. ... Glsm zlem Elpek, is described in a research article ... World Journal of Gastroenterology. , Thrombospondin 1 (TSP-1) is ...
Cached Medicine News:Health News:TV Icon Takes a Shot at Staying Slim 2Health News:GE and Satyam Announce Global Alliance to Provide Healthcare IT Services 2Health News:GE and Satyam Announce Global Alliance to Provide Healthcare IT Services 3Health News:GE and Satyam Announce Global Alliance to Provide Healthcare IT Services 4Health News:Carbon nanotubes that look like asbestos, behave like asbestos 2Health News:Carbon nanotubes that look like asbestos, behave like asbestos 3Health News:More Dialysis Not Better in Acute Kidney Injury 2Health News:Morris Animal Foundation Searches for America's Best Vet With 'Thank Your Vet for a Healthy Pet(SM)' Contest 2Health News:Morris Animal Foundation Searches for America's Best Vet With 'Thank Your Vet for a Healthy Pet(SM)' Contest 3
(Date:8/27/2014)... , Aug. 27, 2014 TWi ... final approval from the United States Food and ... Application (ANDA) for megestrol acetate 125mg/ml oral suspension, ... TWi is the first-to-file and under Hatch Waxman ... of marketing exclusivity.  TWi has completed the pre-launch ...
(Date:8/27/2014)... 2014 Reportbuyer.com has added a ... Terms & Agreements in Pharma, Biotech and ... The Co-development Terms and Agreements in ... understanding and unprecedented access to the co-development ... worlds leading life science companies. The ...
(Date:8/27/2014)... and MENLO PARK, Calif. , ... (OTCQB: DMPI), developer of advanced cancer therapeutics , ... 16th Annual Rodman & Renshaw Global Investment Conference, sponsored ... will take place Tuesday, September 9th at 2:55 p.m. ... the New York Palace Hotel in New ...
Breaking Medicine Technology:TWi Pharmaceuticals Receives US FDA Final Approval on Generic Megestrol Acetate 125mg/ml Oral Suspension 2Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 2Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 3Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 4Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 5Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 6Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 7DelMar Pharmaceuticals To Present At The 16th Annual Rodman & Renshaw Global Investment Conference 2DelMar Pharmaceuticals To Present At The 16th Annual Rodman & Renshaw Global Investment Conference 3DelMar Pharmaceuticals To Present At The 16th Annual Rodman & Renshaw Global Investment Conference 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: