Navigation Links
Breakthrough in cancer therapy

Scientists have developed a way to stop the hair loss associated with drug treatment for cancer. This type of hair loss, known as chemotherapy-induced alopecia (CIA), is a frequent side effect of cancer therapy and is often very distressing for patients at a vulnerable time in their lives.//

Currently, there is no effective way to stop this type of hair loss. The only way doctors can attempt to minimise hair loss is to fit patients with a skull cap to cool the scalp, minimising blood flow, and therefore drug supply to the region.

Recently researchers from the pharmaceutical firm Glaxo Wellcome have designed compounds that have successfully prevented CIA hair loss in rats. CIA occurs because many anticancer drugs work by killing cells that are rapidly dividing. These cells include normal epithelial cells in the hair follicle, as well as tumour cells.

The Glaxo Wellcome team, led by Dr Stephen Davis, tackled the problem by stopping cell division in the hair follicles. They did this by using a compound which blocks the activity of an enzyme, called CDK2. This enzyme plays a central role in the progression of cells through their natural lifecycle.

The compound was applied directly to the scalp of the rats. When the rats were subsequently treated with two widely used anticancer drugs, hair loss at the site of where the compound had been applied was reduced in up to half of the animals.

Professor Gordon McVie, director general of the Cancer Research Campaign in the UK, said hair loss often added to the depression experienced by some cancer patients. He said: "Without a doubt it contributes to a deteriorating self-image, and many people do not believe that their hair will ever grow back even if they are told it is a temporary phenomenon.

Professor McVie said hair loss had become more of a problem with the advent of new drugs taxol and taxotere. Taxol, used for breast and ovarian cancer, is associated w ith the loss of eyebrow hair as well hair on the scalp. Cancer patients who responded to a survey by Glaxo Wellcome ranked hair loss as second only to nausea and vomiting as the most unpleasant side effect of their treatment.


'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer
3. Breakthrough in eye treatment
4. Genetic Breakthrough in Common Eye Problem
5. Breakthrough in Type II Diabetes
6. Breakthrough In Stem Cell Work
7. A Likely Breakthrough For Prostate Cancer Patients
8. New DNA Breakthrough Can Change Future Of Medicine
9. Breakthrough In New Vaccine For Malaria
10. Medical Breakthrough - Kidney Transplant Recipient Survives Without Drugs
11. Breakthrough In Tasmanian Devil Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Final Cut Pro X users can now reveal the media of their split ...
(Date:6/27/2016)... , ... June 27, 2016 ... ... the patient payment industry today announced its strategic partnership with Connance, a ... workflows. , The two companies’ proven, proprietary technology combine to provide health ...
(Date:6/27/2016)... Park, KS (PRWEB) , ... June 27, 2016 , ... ... in retailers of Eyeglasses . , Millions of individuals in the United States ... eyeglasses have become a way to both correct vision and make a fashion statement. ...
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... was developed to enhance the health of felines. The formula is all-natural and is ... herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... OAKLAND, N.J. , June 24, 2016 /PRNewswire/ ... in the design, development and manufacturing of collagen ... and regeneration announced today that Bill Messer ... Sales and Marketing to further leverage the growing ... surgery medical devices. Bill joins the ...
(Date:6/24/2016)... Va. , June 24, 2016 The ... set of recommendations that would allow biopharmaceutical ... (HCEI) with entities that make formulary and coverage decisions, ... the "value" of new medicines. The recommendations ... does not appear on the drug label, a prohibition ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
Breaking Medicine Technology: