Navigation Links
Breakthrough in cancer therapy

Scientists have developed a way to stop the hair loss associated with drug treatment for cancer. This type of hair loss, known as chemotherapy-induced alopecia (CIA), is a frequent side effect of cancer therapy and is often very distressing for patients at a vulnerable time in their lives.//

Currently, there is no effective way to stop this type of hair loss. The only way doctors can attempt to minimise hair loss is to fit patients with a skull cap to cool the scalp, minimising blood flow, and therefore drug supply to the region.

Recently researchers from the pharmaceutical firm Glaxo Wellcome have designed compounds that have successfully prevented CIA hair loss in rats. CIA occurs because many anticancer drugs work by killing cells that are rapidly dividing. These cells include normal epithelial cells in the hair follicle, as well as tumour cells.

The Glaxo Wellcome team, led by Dr Stephen Davis, tackled the problem by stopping cell division in the hair follicles. They did this by using a compound which blocks the activity of an enzyme, called CDK2. This enzyme plays a central role in the progression of cells through their natural lifecycle.

The compound was applied directly to the scalp of the rats. When the rats were subsequently treated with two widely used anticancer drugs, hair loss at the site of where the compound had been applied was reduced in up to half of the animals.

Professor Gordon McVie, director general of the Cancer Research Campaign in the UK, said hair loss often added to the depression experienced by some cancer patients. He said: "Without a doubt it contributes to a deteriorating self-image, and many people do not believe that their hair will ever grow back even if they are told it is a temporary phenomenon.

Professor McVie said hair loss had become more of a problem with the advent of new drugs taxol and taxotere. Taxol, used for breast and ovarian cancer, is associated w ith the loss of eyebrow hair as well hair on the scalp. Cancer patients who responded to a survey by Glaxo Wellcome ranked hair loss as second only to nausea and vomiting as the most unpleasant side effect of their treatment.


'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer
3. Breakthrough in eye treatment
4. Genetic Breakthrough in Common Eye Problem
5. Breakthrough in Type II Diabetes
6. Breakthrough In Stem Cell Work
7. A Likely Breakthrough For Prostate Cancer Patients
8. New DNA Breakthrough Can Change Future Of Medicine
9. Breakthrough In New Vaccine For Malaria
10. Medical Breakthrough - Kidney Transplant Recipient Survives Without Drugs
11. Breakthrough In Tasmanian Devil Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2017)... ... 23, 2017 , ... “Life Under Blankets”: an entrancing story about one ... Under Blankets” is the creation of published author, Kimberly Mitchell, who earned her bachelor’s ... went on to pursue a master’s degree in education in the field of curriculum ...
(Date:1/23/2017)... , ... January 23, 2017 , ... Valentine’s Day is a time when many people ... ones. For those who may be looking for the ideal present, Atlanta-based Perimeter Plastic ... get an additional $25 free. Or, spend $200 and get $50 free. , “A ...
(Date:1/22/2017)... FL (PRWEB) , ... January 22, 2017 , ... Zifam ... customers across the world, recently met with big-name retail buyers at the January ECRM ... evidence of efficacy and uses the utmost safety standards in all of its creations ...
(Date:1/22/2017)... TX (PRWEB) , ... January 22, 2017 , ... ... provide slow results. Often the results of a simple test will take days to ... Any Lab Test Now offers customers direct access to their lab tests, bypassing the ...
(Date:1/21/2017)... Raton, FL (PRWEB) , ... January 21, 2017 , ... ... Germany, announced it is bringing its product to the United States as part of ... over the last 25 years, Alcovit aims to reduce the productions of nasty toxins ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... 2017 A new Transparency Market Research report ... valued at US$0.53 bn in 2013 and is predicted to touch ... between 2014 and 2022. The title of the report is "Non-invasive ... Growth, Trends and Forecast 2014 - 2022." ... Non-invasive prenatal testing (NIPT), also referred to ...
(Date:1/23/2017)... SAN DIEGO , 23 janvier 2017  ResMed ... Winter Haven , Floride) ont annoncé aujourd,hui qu,ils se ... les litiges existants entre les parties. BMC et 3B ... de paiements de droits à ResMed, et ResMed effectuera ... à 3B pour clore le litige de Floride entre ...
(Date:1/23/2017)... Jan 23, 2017 NeuroVive Pharmaceutical AB ... signed a preclinical collaboration agreement with the Children,s Hospital of ... Falk , M.D., a US key opinion leader in the ... ... evaluate compounds from NeuroVive,s research program, NVP015, in certain experimental ...
Breaking Medicine Technology: