Navigation Links
Breakthrough in cancer therapy

Scientists have developed a way to stop the hair loss associated with drug treatment for cancer. This type of hair loss, known as chemotherapy-induced alopecia (CIA), is a frequent side effect of cancer therapy and is often very distressing for patients at a vulnerable time in their lives.//

Currently, there is no effective way to stop this type of hair loss. The only way doctors can attempt to minimise hair loss is to fit patients with a skull cap to cool the scalp, minimising blood flow, and therefore drug supply to the region.

Recently researchers from the pharmaceutical firm Glaxo Wellcome have designed compounds that have successfully prevented CIA hair loss in rats. CIA occurs because many anticancer drugs work by killing cells that are rapidly dividing. These cells include normal epithelial cells in the hair follicle, as well as tumour cells.

The Glaxo Wellcome team, led by Dr Stephen Davis, tackled the problem by stopping cell division in the hair follicles. They did this by using a compound which blocks the activity of an enzyme, called CDK2. This enzyme plays a central role in the progression of cells through their natural lifecycle.

The compound was applied directly to the scalp of the rats. When the rats were subsequently treated with two widely used anticancer drugs, hair loss at the site of where the compound had been applied was reduced in up to half of the animals.

Professor Gordon McVie, director general of the Cancer Research Campaign in the UK, said hair loss often added to the depression experienced by some cancer patients. He said: "Without a doubt it contributes to a deteriorating self-image, and many people do not believe that their hair will ever grow back even if they are told it is a temporary phenomenon.

Professor McVie said hair loss had become more of a problem with the advent of new drugs taxol and taxotere. Taxol, used for breast and ovarian cancer, is associated w ith the loss of eyebrow hair as well hair on the scalp. Cancer patients who responded to a survey by Glaxo Wellcome ranked hair loss as second only to nausea and vomiting as the most unpleasant side effect of their treatment.


'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer
3. Breakthrough in eye treatment
4. Genetic Breakthrough in Common Eye Problem
5. Breakthrough in Type II Diabetes
6. Breakthrough In Stem Cell Work
7. A Likely Breakthrough For Prostate Cancer Patients
8. New DNA Breakthrough Can Change Future Of Medicine
9. Breakthrough In New Vaccine For Malaria
10. Medical Breakthrough - Kidney Transplant Recipient Survives Without Drugs
11. Breakthrough In Tasmanian Devil Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... transport experience for the millions of people who require these medical transport services ... industry through the use of technology. Now, SmartEMS has put forth an industry-changing ...
(Date:6/26/2016)... ... 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... videos a whole new perspective by using the title layers in ProSlice Levels ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of indulgence ... high can result in disappointment, perhaps even self-loathing. However, those who set the bar ... from PsychTests.com reveals that behind the tendency to set low expectations is ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
(Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
Breaking Medicine Technology: