Navigation Links
Breakthrough In New Vaccine For Malaria

The trial of a new malaria vaccine on both humans and mice has been successful and could help eradicate the disease that causes at least one million deaths annually, researchers say//.

Pierre Druilhe and his team at the Pasteur Institute here injected an MSP-3-based vaccine into 30 European volunteers who had never had malaria, re-administering it after one month and again after four months, the online edition of Scientific American reported.

Blood samples were taken one month after each injection. These blood samples were then compared to blood samples from people in France who had no immunity to malaria and blood samples from African people with immunity.

Nearly every vaccinated sample produced an immune response to malaria when it was introduced in vitro and 77 percent produced anti-MSP-3 antibodies.

These antibodies proved to be as good at killing the parasite as those from immune adults and, in some cases, better, destroying up to twice as many.

"This type of immune response, characteristic of immune adults living in malaria-endemic regions, requires, under natural conditions, 10 to 15 years of daily exposure to billions of infected red blood cells," Druilhe notes.

Malaria - a parasite carried by certain mosquitoes - sickens more than 300 million people worldwide every year, according to the World Health Organization. Vaccine development has been hindered by the microscopic parasites adaptability and complexity.

The scientists also did in vivo experiments in mice, infecting them with the parasite and then injecting a small amount of the vaccine-produced antibodies.

The antibodies significantly cut the number of parasites in the blood of these animals and in some cases wiped them out entirely - outperforming even the immune systems of naturally resistant humans.

The vaccine also showed long-lasting promise, with blood from some of the immunised individuals show ing strong resistance a year later.

"This is the first malaria vaccine clinical trial to clearly demonstrate anti-parasitic activity by vaccine-induced antibodies," Druilhe said.

--IANS
'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. ZD1839 Proves Effective - A Breakthrough in fighting Lung Cancer
3. Breakthrough in eye treatment
4. Genetic Breakthrough in Common Eye Problem
5. Breakthrough in cancer therapy
6. Breakthrough in Type II Diabetes
7. Breakthrough In Stem Cell Work
8. A Likely Breakthrough For Prostate Cancer Patients
9. New DNA Breakthrough Can Change Future Of Medicine
10. Medical Breakthrough - Kidney Transplant Recipient Survives Without Drugs
11. Breakthrough In Tasmanian Devil Disease
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/21/2017)... ... July 21, 2017 , ... Adolfson & Peterson Construction (AP) ... Ramsey County Medical Examiners Facility located in Saint Paul, Minn. A single story, ... scheduled to start in late 2017/early 2018. , Staffed by 20 full-time ...
(Date:7/21/2017)... ... July 21, 2017 , ... The Margarian Law Firm has filed a ... its ginger ale for allegedly containing no ginger. Dr. Pepper produces the “Canada Dry” ... plaintiff Gegham Margaryan alleges Canada Dry Ginger Ale claims on its bottle that it ...
(Date:7/21/2017)... OR (PRWEB) , ... July 21, 2017 , ... ... recent weeks Nature’s Tears® EyeMist®, the signature product of her research center at ... with the world’s largest population and the greatest number of sufferers of blindness. ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... TransPixel Volume ... between two clips in the FCPX timeline. This effect isolates horizontal and vertical lines ... this package contains either a rotating or flipping animation and can be changed using ...
(Date:7/20/2017)... ... ... For individuals with extended hospital stays or who are residents of nursing ... specially designed to accommodate patients with a wide range of ailments or special needs, ... has invented the patent-pending PORTABLE ARM REST, a specially designed armrest that features many ...
Breaking Medicine News(10 mins):
(Date:7/1/2017)... Ind. , June 30, 2017 Zimmer Biomet ... quarter sales and earnings conference call will be broadcast live ... a.m. Eastern Time.  A news release detailing the quarterly results ... morning of the conference call. The live audio ... at http://investor.zimmerbiomet.com . It will be archived for replay ...
(Date:6/30/2017)...  Axium Pharmaceuticals Inc. is a pharmaceutical company aimed at utilizing ... dosage forms of existing biologically active molecule. ... Subveta oral ... emulsifying formula, which is designed to prevent precipitation of the ... will provide fast onset of action and is designed to ...
(Date:6/20/2017)... LAGUNA HILLS, Calif. , June 20, 2017 /PRNewswire/ ... validate the use of MMprofiler with SKY92, the company,s ... (MM). In a poster presentation at the 22 nd ... Madrid, Spain , SkylineDx researchers will ... elderly patients. In a separate e-poster ...
Breaking Medicine Technology: