Navigation Links
Brain cells protected by new compounds

Pharmacists have made compounds that can terminate the natural death of brain cells and could treat an extent of neurodegenerative diseases. The protein p53 plays// an important role in getting damaged cells to kill themselves. Its known to be important in cancer - where defective p53 genes allow cancer cells to grow, instead of dying off. Now researchers at the National Institutes of Health are using p53 in a new approach to brain disease.

They have developed a series of compounds that inhibit p53 in the brain. In cell and animal studies, the compounds protect the brain from damage, by keeping cells alive. For example, in a rat model of stroke, animals receiving the compounds survived far longer than those that did not. In another study, p53 inhibitors seemed to protect brain cells from beta amyloid, the toxic protein associated with Alzheimer's disease. However, more work is needed to ensure that the p53 inhibitors are truly specific to the brain, and do not trigger cancer in other cells of the body. Potential applications in humans are widespread - the first trials could be to protect against Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.


'"/>




Page: 1

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Brain death – How to cope with it
3. “Brain fingerprinting”- The new lie detectr
4. Nasal Spray Could Take Drugs Direct to Brain.
5. Virus Combats Brain Tumour
6. Nasal Spray Could Take Drugs Directly to Brain
7. Control of anger disorder connected to Brain Dysfunction
8. High Levels of Protein Linked to Brain Shrinkage
9. Brain damage affects artistic skill
10. Brain changes observed in people with sleep apnoea
11. Brain aneurysms can now be treated with a less invasive procedure
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... , ... December 08, 2016 , ... ... services to families and business owners in and around central Kansas, is joining ... to at-risk youth in the region. , Headquartered in Wichita, Youth Horizons works ...
(Date:12/7/2016)... Wisconsin (PRWEB) , ... December 07, 2016 , ... Kenall ... extraordinary new MedMaster™ MPCNGX . The MPCNGX is a multi-function, sealed, LED luminaire ... right amount of light where and when it’s needed. , A 2’ ...
(Date:12/7/2016)... PHILADELPHIA, PA (PRWEB) , ... December 07, 2016 ... ... story of a women growing up with a schizophrenic mother in a unique, ... social worker who specializes in treating trauma and addictive disorders at her private ...
(Date:12/7/2016)... Fernando Valley, CA (PRWEB) , ... December 07, 2016 , ... ... can be used in several ways to restore a more youthful appearance to the ... , now offer Sculptra, along with a variety of other treatments, to rejuvenate and ...
(Date:12/7/2016)... ... December 07, 2016 , ... When it came time to blow out his candles on ... later, the Pediatric Heart Transplant team at Joe DiMaggio Children’s Hospital surprised his ... the hospital’s 30th heart transplant recipient. , “He was playing at home, when we ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... MOINES, Iowa , Dec. 8, 2016 /PRNewswire/ ... a pharmaceutical company advancing technologies designed to address ... appointment of Chitra Edwin , Ph.D., RAC, ... Compliance. Dr. Edwin will provide leadership for all ... for regulatory approvals, preparation of regulatory submissions, serving ...
(Date:12/7/2016)... 7, 2016 KEY FINDINGS ... such as reducing loss of blood during surgeries, ... arrests, rapid recovery after surgeries, and decreasing risks ... segmented into convective warming system, surface warming systems, ... reduce the stay at hospitals thus, lowering the ...
(Date:12/7/2016)... , Dec 7, 2016 Research and Markets ... and End User - Global Forecast to 2021" report to their ... , , ... 2.12 Billion by 2021, growing at a CAGR of 7.3% during the ... the growing prevalence of cancer and rapidly increasing geriatric population across the ...
Breaking Medicine Technology: