Navigation Links
Brain behind the Brawn: Vital Molecule in the Brain Controls Appetite

Combating obesity is one of the greatest challenges facing researchers today, and recent research holds promise for being a vital breakthrough to contain a growing epidemic.// The World Health Organization has estimated that there are a billion people in the world tackling overweight problems, of them nearly 300 million are obese.

Scientists have narrowed their sights on a new molecule that works on the source of the problem – appetite, the main reason for over weight and obesity. This molecule in the brain is capable of making a person feel full, and satisfied, which is what the world needs to set the obesity record straight.

Masatomo Mori and colleagues at Gunma University in Maebashi, Japan, have identified a key protein called nesfatin-1 which is present in the hypothalamus of rat brains. The hypothalamus is a region of the brain that regulates appetite and temperature. The effects of this molecule were observed on rats; when the molecule was injected into the brains of rats, a feeling of fullness is created , which results in the rats eating much less. This also caused the animals to lose weight.

It was observed that when the investigators injected nesfatin-1 directly into the brains of rats, the animals started eating less. When the protein was injected into their bodies without a break, for 10 days through a drip, the animals were found to lose weight.

To recheck the benefits of this molecule, antibodies blocking the action of nesfatin-1 were injected into the brains of healthy rats. The animals showed an increase in appetite that reflected in them gaining weight within 6 days.

"Nesfatin-1 might be a useful target for the development of drugs to treat obese people," the researchers say. The researchers are planning to conduct human trials that could also lead to the development of a version of the drug that can be normally injected into the body, yet assimilated in the brain to produce the desired effect.

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Brain death – How to cope with it
3. “Brain fingerprinting”- The new lie detectr
4. Nasal Spray Could Take Drugs Direct to Brain.
5. Virus Combats Brain Tumour
6. Nasal Spray Could Take Drugs Directly to Brain
7. Control of anger disorder connected to Brain Dysfunction
8. High Levels of Protein Linked to Brain Shrinkage
9. Brain damage affects artistic skill
10. Brain cells protected by new compounds
11. Brain changes observed in people with sleep apnoea
Post Your Comments:

(Date:11/30/2015)... ... November 30, 2015 , ... Cycling, running, and walking are regular ... meaning the morning of February 28, 2016. , That’s when the 7th annual ... will exercise to help children and families at Joe DiMaggio Children’s Hospital. ...
(Date:11/30/2015)... Baltimore, MD (PRWEB) , ... November 30, 2015 , ... ... has teamed up with Public Television’s Travel With Kids to promote ... follows the Simmons family as they explore international destinations and educate families about the ...
(Date:11/30/2015)... ... 30, 2015 , ... A novel class of antimicrobials that ... in fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major drug-resistant bacterial pathogens, ... molecule analogs that target the functions of SecA, a central part of the ...
(Date:11/30/2015)... ... November 30, 2015 , ... At Grand Dental PC, their ... setting. , When you have dental problems, you need to turn to a dentist ... diagnose and treat your needs, a friendly dentist who counsels you on the best ...
(Date:11/30/2015)... ... ... Using a combination of two blood sugar tests rather than a single test ... study by researchers at the School of Public Health at Georgia State University. , ... Glucose Tests ,” published in Frontiers in Public Health, the researchers noted that 24 ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... FRANCISCO , Nov. 30, 2015 Next ... Designers of Things (DoT ) co-located events covering ... and the Internet of Things, will draw more than ... Jose Convention Center. The events, combined show ... latest technologies. --> ...
(Date:11/30/2015)... 2015 Nautilus Medical Inc. today announced worldwide ... ( ). The release of MatrixRay to the ... (Radiology Society North America) in Chicago ... --> --> MatrixRay ... to radiology studies worldwide via a peer-to-peer exchange network ...
(Date:11/30/2015)... 30, 2015 ... adds a 2015 publication on ... 2015 with comprehensive analysis of recent ... deal types, such as Mergers & ... . --> ...
Breaking Medicine Technology: