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Brain Tumor Drug in Frogs A New Report

is needed. It will have no effect on other cells because it is only capable of recognising and binding to the sugar coating of tumour cells.

Amphinase is in the very early stages of development, so it is likely to be several years and many trials before it could be developed into a treatment for patients, said Professor Acharya and his colleagues Drs Umesh Singh and Daniel Holloway.

Having said that, the early data is promising and through this study we have provided the kind of information needed if approval for use is requested in the future.Amphinase is the second anti-tumour ribonuclease to be isolated by Alfacell Corporation from Rana pipiens oocytes.

The other, ONCONASE(R) (ranpirnase), is currently in late-stage clinical trials as a treatment for unresectable malignant mesothelioma, a rare and fatal form of lung cancer, and in Phase I/II clinical trials in non-small cell lung cancer and other solid tumours.

We are pleased with the superb work performed by Professor Acharya and his talented team at the University of Bath, commented Kuslima Shogen, Alfacells chairman and chief executive officer.

Their work is critical to the continued development and understanding of our family of novel ribonuclease based therapeutics with the potential to help patients suffering from cancer and other dismal diseases.The company is now working on pre-clinical trials of Amphinase with a view to beginning clinical trials in the future.


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