Navigation Links
Bones repair themselves with bone marrow cells

A research project carried out by Juliette van den Dolder at the University of Nijmegen has shown that new bone cells can be grown into bone fractures with the help of specially prepared titanium mesh and bone marrow cells. Researchers inserted a titanium mesh scaffold into a bone fracture in a rat. They allowed bone marrow cells to grow on this. This resulted in new bone growth being stimulated by the bone// marrow cells. They found that bone marrow cells in combination with titanium mesh formed a good culture medium for new bone growth in the case of bone damage. This bone growth was further improved dynamically by the researchers by 'sowing' the cells onto the mesh that lies on a turning plate.

The researchers who tested three differently coated pieces of mesh for cell growth and bone mineral formation found that the mesh containing fibronectin, a bone protein that plays an important role in the growth of new bone, produced the best results. The researchers also tested a cell culture system called flow perfusion system. In this system, fluid containing nutrients and oxygen is pumped top-down through the mesh, whilst at the same time removing waste products. They found that with this system cell growth and bone mineral formation clearly increased.

Earlier, when the bone was damaged, the patient's own bone tissue was used to grow new bone, but usually, bone tissue is unavailable and there are often problems involved in obtaining it. Therefore, such an alternative method developed by Juliette van den Dolder to treat bone defects is of considerable significance. However, there are some more questions to be answered before the method is fully accepted for use. For instance, questions like whether the increase in cell growth and bone mineral formation could be further improved by adapting the flow perfusion system or whether altering the rate at which the fluid is pumped through the mesh could influence the cell growth, are yet be analysed. Also, all of the experiments described were carried out on rats. Thus, the next step would be the investigation of the effectiveness of the tested materials and methods on higher animals and human beings.


'"/>




Related medicine news :

1. Vitamin Shields Brittle Bones
2. Low-Dose Hormones Help the Bones
3. Corticosteroids Safe for Bones
4. Corticosteroids Safe for Bones
5. Milk Not So Good In Building Bones
6. Calcium and Protein Equals Strong Bones
7. Want Strong Bones: Exercise And Eat Right!
8. Magnesium In Diet Strengthens Bones
9. Maternal Vitamin D Supplementation Promises Healthy Bones In Child
10. Raw Vegan Diet Promises Lightweight, Healthy Bones
11. Well Preserved DNA In Fossil Bones Discovered
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2017)... ... January 23, 2017 , ... ... institution’s inaugural K-20 Education Summit to be held March 23-25, 2017 in Tampa, ... Jan. 25, 2017. , The keynote speakers include Dr. Michelle R. Weise, executive ...
(Date:1/23/2017)... ... ... Wooden and plastic balance boards have been around since at least the 1950s and are ... the first and only balance board to use a patent-pending design featuring high-pressure inflation technology ... time as well as skill-level adjustable for all ages and abilities. The board can ...
(Date:1/23/2017)... SC (PRWEB) , ... January 23, 2017 , ... ... is the premiere organization in North America for the scientific development, healthcare training ... 2017 Annual Scientific Session, and its 2017 AAT Member Certification Qualification Courses for ...
(Date:1/23/2017)... ... January 23, 2017 , ... Moisture ... choosing the right method is paramount to success. Selecting an inappropriate measurement method ... where multiple persons use the same equipment. Rare or expensive substances are wasted ...
(Date:1/23/2017)... ... January 23, 2017 , ... Old School Labs™, makers ... Mr. Olympia Classic Physique bodybuilder Breon Ansley to its growing team of brand ambassadors. ... bodybuilder in 2012 and in less than a year was able to turn professional, ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... 2017 NeuroVive Pharmaceutical AB (Nasdaq Stockholm: ... preclinical collaboration agreement with the Children,s Hospital of ... M.D., a US key opinion leader in the mitochondrial medicine ... ... from NeuroVive,s research program, NVP015, in certain experimental disease models. ...
(Date:1/21/2017)... Research and Markets has announced the addition of ... Test (Tumor, Clinical Chemistry, Microbiology, Esoteric), By Type of Lab ... Cancer, HIV/AIDS etc.), Forecast to 2022" report to their ... ... especially clinical lab testing, which has evolved as a major ...
(Date:1/21/2017)... CAMBRIDGE, Mass. , Jan. 20, 2017 ... the Keystone Symposia Conference, "PI3K Pathways in ... Pharmaceuticals, Inc. (NASDAQ: INFI ... oral immuno-oncology development candidate that selectively inhibits ... is able to help overcome resistance to ...
Breaking Medicine Technology: