( han in the inorganic chemistry. She was...)Boffins a Step Closer to Solving Puzzle of Lou Gehrig's Disease,Health

han in the inorganic chemistry. She was more interested, for example, in how the protein influenced the reactivity of the copper or zinc, or how the copper and zinc influenced the structure of the enzyme. She and her colleagues were among the pioneers in taking the copper and zinc out and putting other metals in to see what would happen. Her laboratory put more emphasis on biological factors over time.

"When I moved to UCLA in 1980, we started working on copper-zinc superoxide dismutase in yeast, a model organism, using the then new tools of molecular biology to redesign the protein and make new mutant forms of the protein that would have different inorganic properties," she said.

"We were making mutant forms of this enzyme to study, but with no connection to disease," she added..

Valentine and Bertini have just published an authoritative new textbook called "Biological Inorganic Chemistry: Structure and Reactivity," with co-authors Harry Gray at the California Institute of Technology and the late Edward Stiefel from Princeton University. The textbook is designed for both undergraduate and graduate students.

"All of us who work in the field hope our research will lead to a treatment of ALS. What we really want is to diagnose and prevent ALS before its onset. We're still a long way from that, but we're making progress," Valentine said.

The study is published in Proceedings of the National Academy of Sciences, which is currently online and available in the journal's July 3 print edition.


'"/>




Page: 1 2 3
Related medicine news :

1. Fizzy Logic For A Perfect Drink: Courtesy Boffins
2. Boffins Identify Fifth Gene Behind Joubert Syndrome
3. Boffins Find Link Between Common Sleep Disorder and Hypertension
4. Boffins Identify Molecule That Might Treat Food Allergy
5. Boffins Identify Gene That Helps Regulates Body Weight
6. Boffins Link Atkins Diet With Bowel Cancer
7. Boffins Develop New Technique to Hunt Illness-causing Mutants in Non-gene DNA
8. A Closer Look into Vitamin D and Fractures
9. Scientists Closer To Identifying Gene Connected To Alzheimers
10. Scientist Move A Step Closer To Treating Genetic Obesity
11. Chlamydia Vaccine a Step Closer to Reality