Navigation Links
Body Composition Is Key Player in Controlling Cancer Risks

Scientists have long thought that limiting the calories a person consumes can prevent, or at least slow the progression of certain cancers. But research using mice suggests// that body composition – whether a person is lean or obese – actually is key to reducing cancer risks.

In other words, how the body handles calories is much more important to controlling cancer risks than how many or how few calories are consumed—a finding that could have strong implications for preventing and treating cancer in humans.

In findings published in the issue of Cancer Research, the UAB team found that transgenic mice predisposed to prostate cancer that were lean had a much slower progression of cancer than did heavier mice.

“This study suggests that body composition, being lean as opposed to being obese, has a greater protective effect against cancer,” said Tim R. Nagy, Ph.D., UAB professor of nutrition sciences and study principal investigator. “Excess calorie retention, rather than consumption, confers cancer risk.”

Nagy’s team placed transgenic mice into two controlled environments, either 27 degrees centigrade or 22 degrees centigrade, and fed them equal amounts of food. The mice living at the cooler environment needed more energy to regulate their internal temperature and so burned more calories simply to stay warm. These mice lost weight and were leaner than the mice kept at the warmer temperature.

The mice kept at 27 degrees were heavier and had more fat mass. Cancer in these mice progressed at a much greater rate than in the lean mice. The heavier mice also had higher levels of leptin, a hormone associated with obesity that promotes cancer, and lower levels of adiponectin, a hormone that appears to protect against cancer.

“We believe this is the first study to show that the beneficial effect on cancer risk by reducing the number of calories in the diet is more closely related to leanness or obesity t han previously thought, and not a factor of food intake or total calories ingested,” Nagy said.

Nagy’s team kept two other groups of transgenic mice in the 27 and 22 degree environments. These mice were allowed to eat as much food as they wished. The mice in the cooler environment ate 30 percent more food than the mice in the warmer environment, indicating they required the additional calories to maintain body temperature.

The body composition for both of these groups of mice remained the same; and both had the same level of cancer progression, indicating that the increased calorie intake from the cooler-temperature mice plays no role in cancer protection.

Source-Newswse
SRM
'"/>




Related medicine news :

1. Body Composition Device Gives an Impetus to Infant Studies
2. Crucial Link Between Body Composition and Cancer Risk
3. Teen Players Urged To Wear Helmets and Gloves to Avoid Sports Injuries
4. Jharkhand Ropes in Private Players for Health Scheme
5. Researchers Uncover Critical Player in Cell Communication
6. Zinc – A New Key Player In Brain Circuitr
7. The Cause Behind Water Polo Players’ Sickness Remains A Myster
8. Modified Ligament Surgery Improves Outcomes Players, Athletes
9. Indias Pharmaceutical Industry to Be Global Player: Study
10. Former Official Confesses He Had Sold Steroids to Leading Baseball Players
11. Ex Pro-football Players Saddled With Depression After Retirement
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... (PRWEB) , ... May 24, 2017 , ... ... dental implants in Bayside, NY, who have now spent 10 years as clinical ... New York University (NYU) College of Dentistry. Through the program, private practitioners receive ...
(Date:5/24/2017)... ... May 24, 2017 , ... Patients who want to receive ... now meet with Dr. Joseph Bedich for a consultation, with or without a referral. ... oral health and functionality. , Dr. Bedich offers a variety of cosmetic ...
(Date:5/24/2017)... ... May 24, 2017 , ... Myers Jackson is well known for ... to sell luxury homes anywhere on the planet. The luxury home market is alive ... to Houston city-scapes. A quick search of “11 Spyglass Hill Auction will enlighten you ...
(Date:5/24/2017)... , ... May 24, 2017 ... ... the female reproductive tract in which the endometrial lining of the uterus ... inflammation and pain. Patients experiencing painful intercourse, painful periods, pelvic pain, or ...
(Date:5/24/2017)... ... May 24, 2017 , ... Accordant Technology, ... solutions portfolio. ExtraHop delivers an analytics-first approach, layered with machine learning, that provides ... the datacenter to the cloud to the edge. Through the new partnership, customers ...
Breaking Medicine News(10 mins):
(Date:5/3/2017)... WAYNE, N.J. , May 3, 2017 /PRNewswire/ ... systems that contribute to quality enhancement and cost ... results from a study of contemporary practice demonstrating ... a first-line therapy for critically ill patients. The ... the Company,s newer large volume MEGA ® ...
(Date:5/2/2017)... YORK and LONDON , ... of market intelligence, MarketResearch.com is pleased to announce a ... AB that allows for the marketing and distribution ... analyses through the MarketResearch.com website. The new ... to complete product descriptions and tables of contents from ...
(Date:5/2/2017)... , May 2, 2017  CIVCO Radiotherapy, the ... solutions, announced today that Nat Geissel ... CIVCO since 2012 and has served as vice ... vice president and general manager, and most recently, ... "I am extremely proud of what CIVCO Radiotherapy ...
Breaking Medicine Technology: