Navigation Links
Blood test may aid foretell Alzheimer's

According to study in University of Texas, a novel blood test can detect plaque buildup in mice brains, suggesting a possible new way to predict who might get Alzheimer's disease.Researchers at the School of Medicine in St. Louis said it is unclear whether a similar blood test would work in people, but the findings in the animal studies appeared promising.//

Plaque buildup ruins brain cells and is the cause of Alzheimer's. Some people have a genetic propensity to develop this plaque later in life. The St. Louis team examined 40 mice carrying a genetic mutation to develop buildup up amyloid plaque. Two types of this amyloid protein were measured in the mice's blood. Animals then were injected with an antibody -- an immune system substance that fights infection -- called m266 -- which draws amyloid protein from the brain into the blood.

Within five minutes of the m266 injection, amyloid levels increased dramatically in the blood, indicating how much amyloid protein had built up in the mouse's brain. "That's like unbelievably fast," researcher Dr. David M. Holtzman told United Press International. "We thought if you saw anything it would take days."

The mice's brains were studied 24 hours after injection to affirm whether the levels detected in the blood had accurately reflected how much amyloid protein had built up in the brain tissue. The m266 injection appeared give an accurate picture.

"If this worked the same way in humans, it has the potential to be a predictor on who might develop Alzheimer's later," Holtzman added. M266 is a mouse antibody, Holtzman cautioned, so whether a similar human antibody exists to draw this plaque from the brain into the blood in people remains untested.

It is estimated 4 million Americans have Alzheimer's disease and that figure is expected to double in coming decades as more people live longer, though Holtzman said, "I think that's a big under-estimate," because it doesn't includ e folks with mild dementia.

Alzheimer's is a difficult disease to detect and doctors usually are not able to diagnose it or treat symptoms until the condition has progressed into more advanced stages. There is no cure for Alzheimer's but scientists are interested in an early screening test because earlier detection could mean starting treatment before symptoms -- such as forgetfulness, disorientation and dementia -- become unbearable.

"There's a tremendous ethical question for diagnosing (early) a disease for which this is no cure," James L. Olds, a professor of neuroscience at George Mason University in Fairfax, Va., and director of the Krasnow Institute, cautioned in an interview with UPI.

He said since there is no cure and limited treatment, telling a person they have Alzheimer's when there is no cure means that person must knowingly live with it for a longer period of time -- while they still have most of their cognitive capabilities -- rather than being told when the disease has progressed to the point they are not able to fully comprehend.

That does not mean, however, a blood test would not be useful in understanding what is taking place in the brain, he added. "If we assume what's happening in the blood is happening in the brain," he said, "that's a big red flag that things aren't going well."


'"/>




Related medicine news :

1. Recommendations for Treatment of Blood Pressue
2. Blood Cells Capable of Regenerating Liver
3. Blood clots likely in long travel
4. Hemochromatosis Patients Blood is Safe
5. Blood transfusions beneficial after heart attacks
6. Blood Pressure Drug may slow wasting in burn victims
7. Levels Of Blood Proteins May Help Heart Disease Care
8. Blood test may identify ovarian cancer
9. A Blood test for suicide risk?
10. Blood Pressure Drugs maintain muscle strength
11. Blood test diagnoses heart failure in short time
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether ... latter, setting the bar too high can result in disappointment, perhaps even self-loathing. However, ... their goal. , Research from PsychTests.com reveals that behind the tendency ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief ... a minimum wage raise to $12 an hour by 2020 and then adjusting it yearly ... lost value of the minimum wage, assure the wage floor does not erode again, and ...
(Date:6/24/2016)... York, NY (PRWEB) , ... June 24, 2016 ... ... publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as a ... that “the most beautiful women in the world, and the most handsome men, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Research and Markets ... Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic ... Coating, Parenteral) - Global Forecast to 2021" report ... The global pharmaceutical excipients market is projected to ... of 6.1% in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, ... a Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, ... winners, announced today online at www.diabetesscholars.org by ... 1 diabetes stand in the way of academic and ... the Foundation,s scholarship program since 2012, and continues to ...
Breaking Medicine Technology: