Navigation Links
'Blimp1' Gene Linked To Oily Skin

New research in mice has found that though they do not develop zits, the do have oily skin. Rockefeller University researchers were able to differentiate the cells// in the sebaceous glands that are responsible for the oily skin. The research examines how a sebaceous gland is formed.

In new research, published in the August 11 issue of Cell, Elaine Fuchs, a Howard Hughes Medical Institute investigator at Rockefeller University, settles this argument, showing that at the site where the sebaceous gland adjoins the hair follicle, a unique population of cells exists whose sole job is to make, and maintain, the sebaceous gland.

"We were exploring the expression of a transcription factor called Blimp1, which had surfaced in a genetic screen that we had conducted." explains Fuchs, who is the Rebecca C. Lancefield Professor and head of the Laboratory of Mammalian Cell Biology and Development at Rockefeller. "We were surprised to find that Blimp1 was expressed in a small population of cells within the sebaceous gland. We knew these cells were skin keratinocytes but no one had ever described their existence and therefore, we had no clues about their relationship to the gland."

Valerie Horsley, a postdoc in the Fuchs lab and first author of the paper, had been interested in Blimp1’s role in hair follicle development, and had engineered mice that were missing the Blimp1 gene in their skin. "When the mice were born, they formed normal hair follicles, which was quite disappointing," says Horsley. "But when they were around one month of age I noticed that the mice started getting very oily skin."

The sebaceous glands in mice missing Blimp1 were much larger than in normal skin. This happens in another genetically altered mouse, one overexpessing the c-myc gene, which has been implicated in many different kinds of cancers. Horsley found that Blimp1 usually acts to repress c-myc expression, and in mice without Blimp1 c-myc expression wa
'"/>




Page: 1 2

Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Cough Syrup Ingredient Linked to Stroke
3. Irregular Periods Linked to Diabetes
4. Hormones Linked To Migraines
5. Triglycerides Linked To Stroke Risk
6. Smoking Linked To Low Infant Birth Weight
7. Nausea Linked To Anxiety And Depression
8. Painkiller Linked to Deaths
9. High Levels of Protein Linked to Brain Shrinkage
10. Snoring Linked To Headaches
11. Hormone Therapy Linked to Dementia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Blimp1 Gene Linked Oily Skin

(Date:8/31/2014)... (PRWEB) August 31, 2014 MedixSafe has ... ambulance safes and narcotics lockers . ... the MedixSafe brand for distribution worldwide. “We have now ... Emirates.” Lindsay McCollum, MedixSafe Sales Manager , MedixSafe is ... electronic security and network cabling company with over 30 ...
(Date:8/31/2014)... (PRWEB) September 01, 2014 Recently, BambooIndustry.com, one ... its website with a new selection of bamboo veneers ... to 25 percent off) for these high quality products. The ... The company’s senior spokesman says that its top quality veneers ... to unveil the new designs of bamboo veneers. All these ...
(Date:8/31/2014)... September 01, 2014 With years of hard ... of great secondhand construction machines. Recently, the company has updated ... cheap used cat 966 loaders. All these items are guaranteed ... rates right now. , It is true that all ... are carefully selected by machine specialists. The firm is making ...
(Date:8/31/2014)... UT (PRWEB) August 31, 2014 ... understand the difference between "Bioavailability" and "absorption," Dr. ... NutriGold, responded with great interest. "Bioavailability" and ... abused terms in the supplement industry, second perhaps ... vitamins. Bioavailability and absorption, while related, are ...
(Date:8/31/2014)... 2014 Ticket Down is a ... Dick’s Sporting Goods Park in suburban Denver. The ... games against other international teams on USA soil. ... a new soccer coach aboard, Miguel Herrera, and he has ... before the World Cup in Brazil, the Mexican team played ...
Breaking Medicine News(10 mins):Health News:Memphis-based Electronic Security Specialists Now Offers MedixSafe Narcotics Cabinets Internationally 2Health News:Memphis-based Electronic Security Specialists Now Offers MedixSafe Narcotics Cabinets Internationally 3Health News:High Quality Bamboo Veneers from Bambooindustry.com Receive International Attention 2Health News:Delta Updates Its Wheel Loader Assortment With A Lot Of Cheap Used Cat 966 Loaders 2Health News:Bioavailability Vs Absorption - NutriGold Publishes Tips to Help Consumers Make Informed Decisions for Their Health 2Health News:Bioavailability Vs Absorption - NutriGold Publishes Tips to Help Consumers Make Informed Decisions for Their Health 3Health News:Bioavailability Vs Absorption - NutriGold Publishes Tips to Help Consumers Make Informed Decisions for Their Health 4Health News:Mexico vs. Bolivia Tickets at Dick’s Sporting Goods Park in Commerce City (Denver), CO: Ticket Down Slashes Ticket Prices on Mexico vs. Bolivia Exhibition Game 2Health News:Mexico vs. Bolivia Tickets at Dick’s Sporting Goods Park in Commerce City (Denver), CO: Ticket Down Slashes Ticket Prices on Mexico vs. Bolivia Exhibition Game 3
... http://www.spacapsule.com ), the most advanced method of massage,aromatherapy ... has retained one of Florida,s fastest growing PR ... relaxation experience on,the planet. "We see the ... a matter,of minutes can take you from planet ...
... World-Class Doctors from one of the Nation,s Premier Centers ... Health Care, Research, and Medical Education will Host, ... first-class doctors, NEW YORK, Nov. 12 SIRIUS ... today announced the creation of,"Doctor Radio Powered by NYU ...
... 2007 Rose 12.8% to US$14.3 Million (RMB 107.7 ... Million) Compared to Third Quarter 2006, ... FFHL ), a manufacturer and distributor of,high-quality BOPET plastic ... third quarter and for the nine months,ended September 30, 2007 ...
... November 12 Schlafender Hase GmbH,today released the ... The Text Verification Tool is a patent-protected ... print layout ("artwork") on the data,level - independent ... may be annotated, saved in PDF format and ...
... - Global Landmarks Mark First United Nations World ... will light up in blue to mark the,first United ... the world,s most iconic buildings and sites. The landmarks ... the diabetes circle, the global,symbol for diabetes. The ...
... Families coping with prostate cancer report improved quality of ... patients cancer management, according to a new study. The ... CANCER, a peer-reviewed journal of the American Cancer Society. ... the University of Michigan and co-investigators found that patients ...
Cached Medicine News:Health News:The Ultimate Stress Reliever, SpaCapsule(R), the Capsule that Takes You on a Rejuvenating Journey to the Spa, Retains TransMedia Group for Soothing PR 2Health News:SIRIUS Satellite Radio to Launch 'Doctor Radio,' a Groundbreaking, 24/7 Health and Wellness Channel, in Partnership With NYU Medical Center 2Health News:SIRIUS Satellite Radio to Launch 'Doctor Radio,' a Groundbreaking, 24/7 Health and Wellness Channel, in Partnership With NYU Medical Center 3Health News:SIRIUS Satellite Radio to Launch 'Doctor Radio,' a Groundbreaking, 24/7 Health and Wellness Channel, in Partnership With NYU Medical Center 4Health News:SIRIUS Satellite Radio to Launch 'Doctor Radio,' a Groundbreaking, 24/7 Health and Wellness Channel, in Partnership With NYU Medical Center 5Health News:Fuwei Films Announces Third Quarter 2007 Financial Results 2Health News:Fuwei Films Announces Third Quarter 2007 Financial Results 3Health News:Fuwei Films Announces Third Quarter 2007 Financial Results 4Health News:Fuwei Films Announces Third Quarter 2007 Financial Results 5Health News:Fuwei Films Announces Third Quarter 2007 Financial Results 6Health News:Schlafender Hase Releases Text Verification Tool 4.0 2Health News:World Diabetes Day Lights Up the Skyline 2Health News:World Diabetes Day Lights Up the Skyline 3Health News:Family counseling improves lives of patients and spouses coping with prostate cancer 2
(Date:8/29/2014)... --  Vittamed Corporation , a neurodiagnostics medical device company based ... T. (Teo) Forcht Dagi , MD, DmedSc, MPH, MBA, FACS, ... " Teo Forcht Dagi is an experienced ... venture capital," said Remis Bistras , President and CEO ... strategic, and entrepreneurial expertise to our Board." Dr. ...
(Date:8/29/2014)... -- Research and Markets has announced the ... 2014-2018" report to their offering. ... results in demyelination, axonal transection, and neurodegeneration. The myelin ... the immune system, which targets neurons within the central ... in which the damage of the myelin sheath causes ...
(Date:8/29/2014)... , August 29, 2014 ... and collaboration software has announced a major new deal ... founded by renowned pathology expert, Dr. Marius Nap ... of the 26th European Congress of Pathology which is ... the ExCeL Arena, London where ...
Breaking Medicine Technology:Vittamed Adds Prominent Neurosurgeon and Venture Capitalist T. Forcht Dagi to Board of Directors 2Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 2Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 3Pixcelldata Announces New Deal with Dutch Tele-Pathology Specialists eX-Path Ahead of ECP 2014 2
... The Laserex Tango ophthalmic laser system provides ... SLT laser and a photodisruptor for posterior ... a frequency-doubled Nd:YAG producing pulsed 532 nm ... producing 1064 nm. The appropriate laser can ...
Extremely thin and smooth jaws, jaws open to 5.5 mm, cross action....
Round handle....
5 mm concave jaws, cross action....
Medicine Products: