Navigation Links
'Blimp1' Gene Linked To Oily Skin

New research in mice has found that though they do not develop zits, the do have oily skin. Rockefeller University researchers were able to differentiate the cells// in the sebaceous glands that are responsible for the oily skin. The research examines how a sebaceous gland is formed.

In new research, published in the August 11 issue of Cell, Elaine Fuchs, a Howard Hughes Medical Institute investigator at Rockefeller University, settles this argument, showing that at the site where the sebaceous gland adjoins the hair follicle, a unique population of cells exists whose sole job is to make, and maintain, the sebaceous gland.

"We were exploring the expression of a transcription factor called Blimp1, which had surfaced in a genetic screen that we had conducted." explains Fuchs, who is the Rebecca C. Lancefield Professor and head of the Laboratory of Mammalian Cell Biology and Development at Rockefeller. "We were surprised to find that Blimp1 was expressed in a small population of cells within the sebaceous gland. We knew these cells were skin keratinocytes but no one had ever described their existence and therefore, we had no clues about their relationship to the gland."

Valerie Horsley, a postdoc in the Fuchs lab and first author of the paper, had been interested in Blimp1’s role in hair follicle development, and had engineered mice that were missing the Blimp1 gene in their skin. "When the mice were born, they formed normal hair follicles, which was quite disappointing," says Horsley. "But when they were around one month of age I noticed that the mice started getting very oily skin."

The sebaceous glands in mice missing Blimp1 were much larger than in normal skin. This happens in another genetically altered mouse, one overexpessing the c-myc gene, which has been implicated in many different kinds of cancers. Horsley found that Blimp1 usually acts to repress c-myc expression, and in mice without Blimp1 c-myc expression wa
'"/>




Page: 1 2

Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Cough Syrup Ingredient Linked to Stroke
3. Irregular Periods Linked to Diabetes
4. Hormones Linked To Migraines
5. Triglycerides Linked To Stroke Risk
6. Smoking Linked To Low Infant Birth Weight
7. Nausea Linked To Anxiety And Depression
8. Painkiller Linked to Deaths
9. High Levels of Protein Linked to Brain Shrinkage
10. Snoring Linked To Headaches
11. Hormone Therapy Linked to Dementia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Blimp1 Gene Linked Oily Skin

(Date:11/22/2014)... Today, Dylan Queen, a renowned brand ... wedding dresses; the business offers a wide range of ... ladies worldwide, allowing them to create multiple looks easily. ... this new collection of chic wedding dresses has been ... offered at discounted rates now. Dylan Queen can always ...
(Date:11/22/2014)... 22, 2014 In order to provide better ... of cocktail party dresses. The business knows that a suitable ... occasions. , Now, the party dresses supplier’s high ... off. As the leading company in fashion industry, LunaDress understands ... for every customer. So it always raises the professional level ...
(Date:11/22/2014)... Domestic farmgate milk and dairy ... due to a fall in demand for ... amid the global financial crisis. However, these declines ... dairy manufacturers on the international scene. Strong growth ... growth, primarily due to supply constraints in some ...
(Date:11/22/2014)... This month has been a historical time for ... many positive reviews from some renowned review websites. Recently, the ... launching a new selection of wonderful sexy wedding dresses to ... free shipping and up to an 80% discount on any ... find the most suitable dress at Angeldress.co.uk, which has garnered ...
(Date:11/22/2014)... The Sports Conflict Institute is pleased to announce ... of conflict resolution professionals. Baroff comes to SCI as an ... over 30 years experience as an arbitrator, educator, and ombuds ... connect with SCI and bring my conflict resolution skills and ... a complete sports focus,” says Baroff. , “Roy has a ...
Breaking Medicine News(10 mins):Health News:Dylan Queen Introduces Its New Wedding Dresses 2Health News:LunaDress Unveils Fabulous Cocktail Party Dresses 2Health News:Butter and Dairy Product Manufacturing in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Butter and Dairy Product Manufacturing in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Butter and Dairy Product Manufacturing in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:Sexy Wedding Dresses with Special Discounts Launched by Angeldress.co.uk 2Health News:SCI Announces New Team Member Roy Baroff 2Health News:SCI Announces New Team Member Roy Baroff 3
... chronic kidney disease was conducted in 50 countries on ... Society of Nephrologists and the International Federation of Kidney ... Kidney Day is to emphasize to the masses the ... kidney ailments are common and serious but certainly capable ...
... HIV in the UK has found that sexually transmitted ... antiretroviral-resistant HIV. // ,Researchers from two ... the connection between two phenomena: sexually transmitted diseases (STIs) ... of drug-resistant HIV. Sexually transmitted diseases in either or ...
... and the Medicines for Malaria Venture plan to fund ... Arab Emirates (UAE). The center will focus on developing ... ,Gates Foundation and MMV representatives on Wednesday met with ... the project. The foundation selected the UAE as the ...
... Circumcision may reduce men's chances of contracting HIV by ... procedure may put women at increased risk of infection. ... in Switzerland on the potential impact of male circumcision ... do not abstain from sex while healing from circumcision ...
... quality of life. It is prevalent in nearly 7.8% of ... //4.8 million people in the United States. Although some risk ... largely unknown. ,DES is characterized by a deficiency ... film, ocular surface damage and bothersome symptoms such as ocular ...
... type 2 diabetes increases the risk of death for heart ... heart disease deaths by itself, but together they’ve been found ... analysis of more than 900 patients with established coronary artery ... both type 2 diabetes and symptoms of depression were more ...
Cached Medicine News:Health News:STIs Significantly Increase Risk of Drug-resistant HIV Transmission 2Health News:Circumcision May Lift HIV Risk for Women 2Health News:Dry Eye Syndrome Affects Visual Functions 2Health News:Combination of Depression and Type-2-diabetes Lethal for Heart Patients 2
(Date:11/21/2014)... Clementia Pharmaceuticals, Inc.  announced ... has granted Orphan Medicinal Product Designation for ... the treatment of fibrodysplasia ossificans progressiva (FOP). ... disease characterized by painful, recurrent episodes of ... bone formation. This process, known as heterotopic ...
(Date:11/21/2014)... 2014 /PRNewswire/-- CANTEL MEDICAL CORP. (NYSE: CMN ) announced ... will be presenting at the 26 th Annual Piper ... New York . The formal presentation is ... In addition, Mr. Krakauer and Jorgen B. Hansen , ... during the day. An audio webcast will ...
(Date:11/21/2014)... November 2014 Michael DeMarco (42) ... des 14. Februar 2014 zugetragen hat. Seine Tochter Aly ... Video - http://youtu.be/5cVoMCe0uiE ... mein morgendliches Training zu machen", erzählt Michael DeMarco ... Zeit begeisterte Anhänger der CrossFit-Trainingsmethode. Ich war auf ...
Breaking Medicine Technology:Clementia Pharmaceuticals Receives EMA Orphan Medicinal Product Designation for Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva 2Clementia Pharmaceuticals Receives EMA Orphan Medicinal Product Designation for Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva 3Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 2Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 3
... 17, 2012  Eisai announced today that 15 abstracts highlighting new ... Annual Meeting of the American Society of Clinical Oncology (ASCO), ... 2012. These studies highlight Eisai,s current product ... and their families affected by cancer. "Our ...
... Janssen Pharmaceuticals, Inc. today announced the results ... ER (tapentadol) extended-release tablets were significantly more effective ... with chronic moderate to severe, painful diabetic peripheral ... at the 31st Annual Scientific Meeting of the ...
Cached Medicine Technology:Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 2Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 3Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 4Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 5Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 6Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 7Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 8Eisai Oncology to Present New Research on Product Portfolio and Pipeline at ASCO Annual Meeting 9Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 2Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 3Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 4Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 5Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 6Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 7Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 8Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 9Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 10Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 11Phase 3 Data Show NUCYNTA® ER (tapentadol) Extended-Release Tablets Provide Pain Management for Patients with Diabetic Peripheral Neuropathy (DPN) 12
... The Featured Products ... at Mediflex and are ... modular in regular or ... come equipped with insulation, ...
... Featured Products are kept ... and are offered as ... regular or extra long ... with insulation, flush ports, ...
... AEM Laparoscopic Instruments incorporate a layered design ... shielded and monitored to prevent stray electrosurgical ... caused by insulation failure or capacitive coupling; ... shield built into all AEM Instruments provides ...
... The Featured Products ... at Mediflex and are ... modular in regular or ... come equipped with insulation, ...
Medicine Products: