Navigation Links
Bladder Pain Suppressed By Marijuana-Derived Drug

IP 751, a derivative of Marijuana has been found to suppress bladder pain associated with interstitial cystitis (IC) in animal models//. The synthetic drug is a analog of a metabolite of THC, the principal component of marijuana. The results of the new study presented at the annual meeting of the American Urological Association highlights that the drug can be used in the treatment of hypersensitive bladder disorders and similar urological diseases.

IP 751 is a potent anti-inflammatory and a powerful analgesic, although the mechanisms by which it works are unknown. However, since the drug is insoluble in water, its administration directly into the bladder is difficult.

For the study, researchers at the University of Pittsburgh School of Medicine addressed the hydrophobic properties of IP 751 by introducing the drug into a liposome, a tiny sac surrounded by fatty acids, allowing for the drug to be introduced directly into the bladders of rat models of varying degrees of bladder inflammation. IP 751 significantly suppressed bladder overactivity in both animal models. Bladder overactivity is the underlying cause of irritation and pain in the bladder.

‘Interstitial cystitis is a difficult disease to treat, and not all treatments work well on all patients,’ said Michael B. Chancellor, M.D., professor of urology and gynecology at the University of Pittsburgh School of Medicine. ‘Any new option we can give our patients to alleviate their painful symptoms is very important.’

According to the National Institute of Diabetes and Digestive and Kidney Diseases, 700,000 Americans have IC; 90 percent are women. IC is one of the chronic pelvic pain disorders, defined by recurring discomfort or pain in the bladder and surrounding pelvic region. Symptoms vary and can include any combination of mild to severe pain, pressure and tenderness in the bladder and pelvic area, and an urgent and/or frequent need to urinate. In IC, the bladder wall may be come scarred or irritated, and pinpoint bleeding may appear on the bladder wall.

Source: Eurekalet
'"/>




Related medicine news :

1. Chemotherapy Effective for Bladder Cancer
2. Dogs Can Sense Bladder Cancer
3. More Causes of Bladder Cancer Identified
4. More Dependable Screening Test For Bladder Cancer
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Shy Bladder Syndrome: A Social Phobia Or Functional Disorder Of Micturition?
7. Coaching In Labor Could Increase Bladder Problems
8. Measuring Urinary Protein Helps In Detecting Recurrent Bladder Cancer
9. Brain holds the key to Overactive Bladder
10. Smoking Marijuana Increases The Risk Of Bladder Cancer
11. Bladder Surgery Patients Warned About Risk Of Bladder Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/22/2017)... ... May 22, 2017 , ... Galena, Alaska, has a ... Circle made big headlines when it was targeted to build a nuclear plant by ... Alaska,” former city manager Marvin L. Yoder describes the journey to get power to ...
(Date:5/22/2017)... (PRWEB) , ... May 22, 2017 , ... ... sponsor a program on Wellocity to empower WeightZone Factor members to track their ... and get an excellent health education, all on their mobile phones. It also ...
(Date:5/21/2017)... ... ... Cornell, 52, was found dead on the night of Wednesday, May 17, 2017. It can ... the rock industry would take his own life, but the extremely talented and admired ... a role in the death of Chris Cornell . , Depression and Drug Use ...
(Date:5/21/2017)... ID (PRWEB) , ... May 20, 2017 , ... ... financial integration systems between ABC Financial Services and financial systems. , ... link or exported files that are electronically processed through GetLinked into their club’s ...
(Date:5/21/2017)... ... 2017 , ... Pot. Reefer. Grass. Mary Jane. No matter what people call ... like never before. More than a map, new social marketplace Weedable goes ... – and for the first time – each other. A social marketplace like no ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... 2017  Semler Scientific, Inc. (OTCQB: SMLR), an ... improve the clinical effectiveness and efficiency of healthcare ... quarter ended March 31, 2017. ... to identify when preventive care options are appropriate, ... heart attacks or strokes occur," said Doug ...
(Date:5/6/2017)... N.Y. , May 5, 2017  Hill-Rom Holdings, ... will add approximately 100,000 square feet to its Welch ... September 2016 its commitment to bring more than 100 ... , where Welch Allyn has maintained a significant presence ... help accommodate these new positions, a large portion of ...
(Date:5/4/2017)... , May 4, 2017  DarioHealth Corp. (NASDAQ: ... health and big data solutions, today announced that it ... Company, and STI Technologies Limited to lower diabetes healthcare ... Through STI,s innoviCares card, which is available throughout all ... DarioHealth customers will be eligible for additional savings when ...
Breaking Medicine Technology: