Navigation Links
Bladder Pain Suppressed By Marijuana-Derived Drug

IP 751, a derivative of Marijuana has been found to suppress bladder pain associated with interstitial cystitis (IC) in animal models//. The synthetic drug is a analog of a metabolite of THC, the principal component of marijuana. The results of the new study presented at the annual meeting of the American Urological Association highlights that the drug can be used in the treatment of hypersensitive bladder disorders and similar urological diseases.

IP 751 is a potent anti-inflammatory and a powerful analgesic, although the mechanisms by which it works are unknown. However, since the drug is insoluble in water, its administration directly into the bladder is difficult.

For the study, researchers at the University of Pittsburgh School of Medicine addressed the hydrophobic properties of IP 751 by introducing the drug into a liposome, a tiny sac surrounded by fatty acids, allowing for the drug to be introduced directly into the bladders of rat models of varying degrees of bladder inflammation. IP 751 significantly suppressed bladder overactivity in both animal models. Bladder overactivity is the underlying cause of irritation and pain in the bladder.

‘Interstitial cystitis is a difficult disease to treat, and not all treatments work well on all patients,’ said Michael B. Chancellor, M.D., professor of urology and gynecology at the University of Pittsburgh School of Medicine. ‘Any new option we can give our patients to alleviate their painful symptoms is very important.’

According to the National Institute of Diabetes and Digestive and Kidney Diseases, 700,000 Americans have IC; 90 percent are women. IC is one of the chronic pelvic pain disorders, defined by recurring discomfort or pain in the bladder and surrounding pelvic region. Symptoms vary and can include any combination of mild to severe pain, pressure and tenderness in the bladder and pelvic area, and an urgent and/or frequent need to urinate. In IC, the bladder wall may be come scarred or irritated, and pinpoint bleeding may appear on the bladder wall.

Source: Eurekalet
'"/>




Related medicine news :

1. Chemotherapy Effective for Bladder Cancer
2. Dogs Can Sense Bladder Cancer
3. More Causes of Bladder Cancer Identified
4. More Dependable Screening Test For Bladder Cancer
5. Marijuana-Derived Drug Promises Hope In Treating Bladder Infection
6. Shy Bladder Syndrome: A Social Phobia Or Functional Disorder Of Micturition?
7. Coaching In Labor Could Increase Bladder Problems
8. Measuring Urinary Protein Helps In Detecting Recurrent Bladder Cancer
9. Brain holds the key to Overactive Bladder
10. Smoking Marijuana Increases The Risk Of Bladder Cancer
11. Bladder Surgery Patients Warned About Risk Of Bladder Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/18/2017)... , ... January 18, 2017 , ... At Hallmark Nameplate, ... announce that they have achieved certification to ISO 13485. This certification is another way ... up to date products and services that they need. , The ISO 13485 Certification ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... support an aid project with the donation of cochlear implants. In February 2017, ... hearing and thus a fair chance of leading an independent life. This engagement ...
(Date:1/17/2017)... ... , ... January is National Stalking Awareness Month (NSAM), now in its fourteenth year, ... commit the crime of stalking, a very real danger to many in our community. ... stalking and other crimes. , “Stalking: know it. Name it. Stop it.”—so reads the theme ...
(Date:1/17/2017)... (PRWEB) , ... January 17, 2017 , ... For breast ... Cancer Symposium (SABCS) or those who desire a more intimate review and analysis of ... Cancer – Bench to Bedside—is being offered by Imedex on February 4, 2017 in ...
(Date:1/17/2017)... St. Petersburg, Florida (PRWEB) , ... January 17, 2017 , ... ... and the Producers of AsSeenOnTV.pro will be featuring DRTV campaigns regarding the topic of ... year to become a better version of themselves. What better way to commit to ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... Jan. 18, 2017  Eisai Inc., the U.S. ... that it is participating in Access Accelerated, a ... (NCDs) prevention, treatment and care in low and ... the first multi-stakeholder, international initiative in the field ... including Eisai, in collaboration with the World Bank ...
(Date:1/18/2017)... --  Robust competition in the private marketplace is resulting ... according to a new study by the ... first to examine the share of prescription medicine spending ... (PBMs), health plans and other stakeholders in the supply ... to show what happens when the list price of ...
(Date:1/17/2017)... 17, 2017 Secretary of Health Dr. ... Gary Tennis are warning Pennsylvanians of the ... overdose deaths from the drug in Beaver ... to sedate large animals and is not meant for ... into contact with it," Secretary Murphy said. "It,s absolutely ...
Breaking Medicine Technology: