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Bisphenol A (BPA) linked with breast cancer

Urine and blood concentrations of BPA metabolites in humans are much, much smaller than exposures used in this study, says Widlanski.

"Unfortunately, we simply can't mimic long-term exposure to bisphenol A," he said, since it's unethical to give human test volunteers any chemical with an unproven safety record, especially over the long term.

"So, we have to use a larger concentration to mimic the effects of long-term exposure," he said. "No one knows if that's a valid way to do that or not." Animal studies are a logical next step, he said, but they can never fully replicate potential effects in humans.

"The real crux of the matter is that we are surrounded in our environment by chemicals that are pseudo-oestrogenic, not just BPA," Widlanski added. "It's the cumulative effect of all of these compounds together that one needs to worry abot."
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