( efects in mice. This is a first step ...)Bisphenol A (BPA) linked with breast cancer,Health

efects in mice. "This is a first step, and a really important first step," she said.

But according to Dr Widlanski the results should be viewed carefully, as they had only shown this process in the lab. "We have only demonstrated a possible mechanism that explains what people have been speculating about for years."

According to him, even if BPA had a role in cancer growth, it may be in combination with several other cancer-causing compounds that were responsible for the disease. More research was needed on BPA, according to cancer experts.

Professor David Phillips, from Cancer Research UK, said: "They have shown how BPA could be taken up and processed by cancer cells, but the study has not shown any human cancer risk from this level of exposure." The bottom line, according to Widlanski: "If you weren't alarmed yesterday about BPA, then you shouldn't be alarmed today. Nothing we have shown changes the innate danger. We have just reported a mechanism."

BPA was defended by the plastic industry. "BPA has been extensively studied for its potential to cause cancer, including lifetime studies in rats and mice," said Steven Hentges, executive director of the Polycarbonate Business Unit at the American Plastics Council, which represents the industry.

According to him, governments allover the world have commissioned their own studies on BPA, "and, in every case, have concluded that BPA is not likely to pose a carcinogenic risk to humans."

Hentges sees serious flaws in the study. "First of all, it's an in vitro study," he said. "You can't extrapolate from a cell culture and say much of anything about breast cancer." And, he said, tests conducted recently by the U.S. Centers for Disease Control and Prevention (CDC) found average levels of BPA in human urine to be infinitesimally small -- about one part per billion.”

According to Widlanski short-term, in vitro studies cannot fully explain human disease.
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