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Bisphenol A (BPA) linked with breast cancer

According to researchers, bisphenol A, a chemical used in plastic bottles and other household products may be linked to the development of breast cancer.//

Bisphenol A, “pseudo-oestrogen” which mimics female hormones, can stimulate cancer cells, when present in high concentrations.

Though previous studies suggest that natural changes in the oestrogen-like chemical after entering the body makes it harmless. However, a U.S. study revealed that these chemicals retain their carcinogenic properties even after modification inside the body.

But this doesn’t prove that there is a link between this chemical and cancer in human, according to cancer charities. They added that more research was required.

BPA is used in the production of food containers, CDs and DVDs, car parts and in dental sealants. According to previous researches, BPA escapes from products and may be absorbed at low concentrations into the body.

Researchers from Indiana University and the University of California conducted a study on BPA and its possible link with cancer development. Their study was recently published in the journal Chemistry & Biology.

In this study cancer cells and enzymes were subjected to extremely high concentrations of the chemical - higher than those normally experienced by humans. This was done with the aim of stimulating the cumulative effect of low BPA concentrations during a human's lifetime, according to Dr. Theodore Widlanski.

"We've shown that modified versions of BPA likely to be formed in the body do stimulate breast tumour cell growth in vitro [in the lab]. Enzymes present on the surface of breast tumour cells appear to convert the modified BPA back into BPA."

"These guys were aiming at what I'd say was the 'missing link,'" added Patricia Hunt, a molecular bioscience professor at Washington State University who has conducted her own studies suggesting a link between BPA and birth d
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