Navigation Links
Birth Defects Caused By Acne Medication Can Be Minimized By Voluntary Pregnancy Prevention

Isotretinoin is a drug used to treat severe acne that woks by reducing the sebum secretion. Research done on the effect of the drug in pregnant women reveals that it can cause birth defects//. In view of the potential risks, the U.S. Food and Drug Administration and the drug manufacturers developed a voluntary pregnancy prevention program (PPP) in 1988 to try and prevent conception in women taking the drug.

It was soon placed by the SMART program (System to Manage Accutane Related Teratogenicity) that placed more emphasis on pregnancy testing and contraception. The FDA launched a new plan called the iPLEDGE with stricter requirements that required patients and doctors to register in an electronic database before the drug can be dispensed. It also includes the previously stated requirements regarding pregnancy tests and birth control.

A survey was conducted among 34 women who became pregnant while taking isotretinoin. These women had contacted a birth defect information service seeking information on the effects of isotretinoin. The purpose of the survey was to evaluate how the drug was dispensed in women who subsequently became pregnant and to identify possible reasons for failure in preventing conception.

The results of the OTIS survey show that the majority of women who participated were treated for less severe disease than is recommended in the SMART program. A total of 24 percent of the women reported receiving contraception counseling while taking the drug.

In addition, the results showed that healthcare professionals and their patients failed to comply with a number of key SMART and/or PPP requirements. According to these requirements, women must have two negative pregnancy tests before receiving a prescription, yet 76 percent of the women in the study said they did not have a second pregnancy test during menstruation. Nearly 35 percent of the women surveyed said they did not have monthly pregnancy tests before the second prescription.

SMART also requires women to use two forms of birth control simultaneously while taking isotretinoin, yet only 62 percent of the women reported using birth control and only 29 percent of these women reported using two forms of contraception. In addition, only 53 percent of the women reported signing the informed consent required by SMART prior to taking the drug.

The study has given valuable insights into factors that hinder the success of pregnancy prevention programs. If these issues are addressed in an appropriate way, then the birth defects caused by such teratogens can be minimized. After all, it is our responsibility to promise a healthy generation, menstruation, negative pregnancy test
'"/>




Related medicine news :

1. Birth weight key factor in heart diseases
2. FDA Approves Birth Control Skin Patch
3. IVF technique May Increase The Risk Of Birth Defects
4. Smoking Linked To Low Infant Birth Weight
5. Unpredictable Premature Birth
6. New Birth Control Pills increase the stroke risk
7. Epilepsy Drugs Can Enhance Risk of Birth Defects
8. Sex timing has no impact on risk of Birth defects
9. Birth weight may be influenced by genes
10. Dental Procedure Reduces Preterm Births
11. Low Birth Weight infants could have Problems in the Future
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... a leader in post-acute health care, have expanded their existing home health joint ... Health. , AccentCare has been operating a joint venture home health company with ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa ... contributed a medical article to the newly revamped Cosmetic Town journal ... the hair transplant procedure known as Follicular Unit Extraction (FUE). , ...
(Date:10/12/2017)... ... ... Leading pediatric oncology experts at Children’s National Health System will join ... International Society of Paediatric Oncology (SIOP) Oct. 12-15. Chaired by Jeffrey Dome, ... at Children’s National, and Stephen P. Hunger, M.D., Chief of the Division of ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... 19, 2017   ZirMed Inc ., a recognized leader ... that it has been ranked #1 by its users for ... Rankings 2017 User Survey. ZirMed was recognized as the top-ranked ... and medical centers over 200 beds and holds one of ... user survey history. ...
(Date:9/13/2017)... 13, 2017   OrthoAtlanta has been named the ... Host Committee (AFHC) for the 2018 College Football Playoff (CFP) ... at Mercedes-Benz Stadium in Atlanta, Georgia . ... "I,m In" campaign, participating in many activities leading up to, ... ...
(Date:9/12/2017)... SAN FRANCISCO , Sept. 12, 2017 /PRNewswire/ ... Lifecycle Management Solutions (VLMS), is pleased to announce ... as a member of its Board of Directors ... 2017. ValGenesis VLMS enables life science companies to ... eliminate the use of paper in this process. ...
Breaking Medicine Technology: