Navigation Links
Birth Defects Caused By Acne Medication Can Be Minimized By Voluntary Pregnancy Prevention

Isotretinoin is a drug used to treat severe acne that woks by reducing the sebum secretion. Research done on the effect of the drug in pregnant women reveals that it can cause birth defects//. In view of the potential risks, the U.S. Food and Drug Administration and the drug manufacturers developed a voluntary pregnancy prevention program (PPP) in 1988 to try and prevent conception in women taking the drug.

It was soon placed by the SMART program (System to Manage Accutane Related Teratogenicity) that placed more emphasis on pregnancy testing and contraception. The FDA launched a new plan called the iPLEDGE with stricter requirements that required patients and doctors to register in an electronic database before the drug can be dispensed. It also includes the previously stated requirements regarding pregnancy tests and birth control.

A survey was conducted among 34 women who became pregnant while taking isotretinoin. These women had contacted a birth defect information service seeking information on the effects of isotretinoin. The purpose of the survey was to evaluate how the drug was dispensed in women who subsequently became pregnant and to identify possible reasons for failure in preventing conception.

The results of the OTIS survey show that the majority of women who participated were treated for less severe disease than is recommended in the SMART program. A total of 24 percent of the women reported receiving contraception counseling while taking the drug.

In addition, the results showed that healthcare professionals and their patients failed to comply with a number of key SMART and/or PPP requirements. According to these requirements, women must have two negative pregnancy tests before receiving a prescription, yet 76 percent of the women in the study said they did not have a second pregnancy test during menstruation. Nearly 35 percent of the women surveyed said they did not have monthly pregnancy tests before the second prescription.

SMART also requires women to use two forms of birth control simultaneously while taking isotretinoin, yet only 62 percent of the women reported using birth control and only 29 percent of these women reported using two forms of contraception. In addition, only 53 percent of the women reported signing the informed consent required by SMART prior to taking the drug.

The study has given valuable insights into factors that hinder the success of pregnancy prevention programs. If these issues are addressed in an appropriate way, then the birth defects caused by such teratogens can be minimized. After all, it is our responsibility to promise a healthy generation, menstruation, negative pregnancy test
'"/>




Related medicine news :

1. Birth weight key factor in heart diseases
2. FDA Approves Birth Control Skin Patch
3. IVF technique May Increase The Risk Of Birth Defects
4. Smoking Linked To Low Infant Birth Weight
5. Unpredictable Premature Birth
6. New Birth Control Pills increase the stroke risk
7. Epilepsy Drugs Can Enhance Risk of Birth Defects
8. Sex timing has no impact on risk of Birth defects
9. Birth weight may be influenced by genes
10. Dental Procedure Reduces Preterm Births
11. Low Birth Weight infants could have Problems in the Future
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/4/2016)... ... 03, 2016 , ... The Lymphoma Research Foundation (LRF) – ... serving the lymphoma community through a comprehensive series of education programs, outreach initiatives ... New York City, with long-time partners The Paul Foundation, on November 10, 2016. ...
(Date:12/4/2016)... ... December 03, 2016 , ... ... Entrepreneurial Company in the Dallas area” Tuesday evening at the 26th Annual SMU ... presented by SMU's Cox School’s Caruth Institute for Entrepreneurship. Dallas 100™, co-founded by ...
(Date:12/4/2016)... , ... December 04, 2016 , ... Responsible dental care ... must brush properly to achieve optimal results. This important necessity inspired an inventor from ... for a way to ensure that people break or avoid bad techniques of brushing ...
(Date:12/2/2016)... SAN DIEGO, Calif. (PRWEB) , ... December 02, 2016 , ... ... Recognition Event at the Hard Rock Hotel San Diego honoring the 2016 MPN Heroes—eight ... as myeloproliferative neoplasms (MPNs) by going above and beyond the standard of care, demonstrating ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... announces the launch of its 60-day free trial program for all of the ... make the offer a truly hassle free experience. , FlexiSpot’s unique desktop risers ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Dec. 2, 2016  PipelineRx, a leading medication management ... offering demonstrations of its SaaS-based telepharmacy platform, ... Pharmacists 2016 Midyear Clinical Meeting and Exhibition, December ... With nearly 300 hospital clients nationally, the Company ... designed to dramatically improve pharmacy operations, enhance patient ...
(Date:12/2/2016)... -- On Thursday, December 1st 2016, the ... development and innovation in the biopharmaceutical industry at its ... the presence of Sergey Tsyb, Vice Minister of Industry ... , Natalia Sanina, First Vice Chairman of the State ... Roszdravnadzor, National Service of Control in Healthcare, Sergey Muravev, ...
(Date:12/2/2016)... Dec. 2, 2016  Eli Lilly and Company (NYSE: ... for 2017 and provide updated financial guidance for 2016 ... a conference call on that day with the investment ... guidance. The conference call will begin at ... can access a live webcast of the conference call ...
Breaking Medicine Technology: