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Bayer and Onyx Submit Supplemental New Drug Application for Nexavar to Treat Liver Cancer

most common cancer in the world and the third leading cause of cancer-related deaths globally.

Over 600,000 cases of HCC are diagnosed globally each year(about 19,000 in the United States and 32,000 in the European Union) and in 2002 approximately 600,000 people (about 13,000 Americans and 57,000 Europeans) died of HCC.

"This filing exemplifies our commitment to providing valuable therapeutic options for significant unmet needs in cancer treatment," said Hank Fuchs, M.D., executive vice president and chief medical officer of Onyx.

"We believe that Nexavar will become the reference standard of care in HCC, and will help advance our development program, which includes clinical trials studying Nexavar alone and in combination with other therapies across many different cancer types, including melanoma, non-small cell lung and breast cancer."




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