Navigation Links
Basis for Nerve fiber Damage in Multiple Sclerosis Discovered

antly, these are the first antibodies to be identified with axon activity, which is a new area researchers are exploring in the pathology of MS." MS is a chronic central nervous system disease that can cause blurred vision, poor coordination, slurred speech, numbness, acute fatigue and, in its most extreme form, blindness and paralysis. Some 400,000 Americans have this disease. Its causes are unknown, and symptoms are unpredictable and vary greatly in severity. Much MS research is focused on an autoimmune process in which T-cells attack and damage myelin, the fatty insulating tissue of axons. These T-cells do not attack axons themselves; the process of demyelination interrupts electrical impulses that run through these nerve fibers, thus causing MS symptoms. Demyelination has been considered the central feature of MS.

Recently, however, Qin has been among a group of researchers who have discovered that B-cells too are involved with the autoimmune response to MS. Instead of targeting myelin, these B-cells attack axons directly. Axons are the long, slender fibers of a neuron that serve as the primary transmission lines of the nervous system, and as bundles they help make up nerves.

Research at UCI and elsewhere has shown that myelin grows back if the T-cell autoimmune response is turned off, and drugs exist or are in development to block demyelination. Axons, in turn, repair very slowly, which implies that B-cell attacks on axons may have a significant impact on the chronic central nervous system damage caused by MS. "Since this area of research is in its early stage, it’s important to understand the process by which these B-cell responses happen," Qin said. "Hopefully, by identifying these two crucial enzymes, it will lead to a greater understanding of MS and lead to more effective treatments for people who live with this disease."

Johanna Kolln, Hui-Min Ren, Reng-Rong Da, Yiping Zhang, Dr. Michael Olek, Dr. Neal Hermanowicz, Lutz
'"/>




Page: 1 2 3

Related medicine news :

1. Genetics Might BE The Basis For Chronic Fatigue Syndrome
2. Molecular Basis Of ALS Found
3. Biological Basis for Homosexuality
4. Biological Basis Behind a Couch Potato
5. Researchers Develop Basis For Experimental Melanoma Treatment
6. Researchers Investigate Molecular Basis of Memory
7. Epilepsy Drug Helps Diabetic Nerve Damage
8. World’s First Nerve Stem Cells Produced
9. Children With Epilepsy Can Be Treated With Nerve Stimulation
10. FDA Approved Nerve-Stimulation Therapy Now Available In New York
11. Doctors Finish Mother-To-Son Nerve Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Basis for Nerve fiber Damage Multiple Sclerosis Discovered

(Date:7/11/2014)... London, UK (PRWEB) July 11, 2014 ... segment of the in-vitro diagnostics industry, which is expected ... next ten years. The sector owes its growth to ... threat to people’s health worldwide and a major factor ... diagnostic technologies, threat of bio-terrorism, and a broader availability ...
(Date:7/11/2014)... The report, “Specialty Synthetic Fibers & Glass ... 2018,” defines and segments the specialty synthetic fibers ... forecast of the volumes and values of types ... aramids, UHMW Polyethylene, carbon fiber, partially oxidized polyacrylonitrile ... PBO fiber, and liquid crystal polymer fiber and ...
(Date:7/11/2014)... GA (PRWEB) July 11, 2014 Datalogic ... step in improving sanitation hospital wide. With their new ... the spread of disease, like the devastating MRSA, which ... The Gryphon GD4400-HC 2D and the Gryphon ... 2D barcodes and can even read barcodes off of ...
(Date:7/11/2014)... July 11, 2014 Operators ... $50 billion in fuel costs now that ... current GHG standards are phasing ... it upon themselves to install new features ... 1.    Idle reduction technologies , 2.    Efficient driveline components ...
(Date:7/11/2014)... FRIDAY, July 11, 2014 (HealthDay News) -- Children ... greater risk for complications and potentially even death ... a new study. However, the Johns Hopkins ... "miniscule." The researchers analyzed data on nearly ... United States underwent over a 22-year period. ...
Breaking Medicine News(10 mins):Health News:World Virology and Bacteriology Testing Sector Discussed in Comprehensive VPG Research Report Published at MarketPublishers.com 2Health News:World Virology and Bacteriology Testing Sector Discussed in Comprehensive VPG Research Report Published at MarketPublishers.com 3Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 2Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 3Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 4Health News:Stop Spreading Disease with the New Disinfectant-Ready Bar Code Scanner 2Health News:Stop Spreading Disease with the New Disinfectant-Ready Bar Code Scanner 3Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 2Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 3Health News:Emergency Surgeries on Weekends Riskier for Kids: Study 2
... held belief, moderate levels of psychological stress in the ... to research conducted at the Johns Hopkins University and ... The study is published in the May/June 2006 edition ... that modest anxiety and daily stress during pregnancy is ...
... found out what it is that can induce maximum ... Their finding has revealed that toddlers learn the maximum ... they can associate with. ,The researchers conducted ... best-engaged toddlers. In the first, they tested differences in ...
... a genetic disorder which completely affects the immune system. ... gene //therapy was successfully used to cure this life ... School Of Veterinary Medicine and the National Institute of ... acts as a vector for the correct gene of ...
... of Pennsylvania and Temple University Plasminogen Activator Inhibitor Type ... the eye. This is a protein which is founding ... researchers, led by Mina Massaro-Giordano, M.D., of the University ... of the Sbarro Institute for Cancer Research at Temple ...
... in the May issue of Cancer Cell says that ... the mystery of how cancer progresses.// This molecule was ... cells both in vivo as well as in vitro. ... small molecule kinase inhibitors must display a broad reactivity ...
... the American Journal of Respiratory and Critical Care Medicine says ... loss in lung capacity equivalent to what usually happens after ... ,An average loss of 372 milliliters was noted, ... This loss is at least 10 times more than the ...
Cached Medicine News:Health News:Children Benefited By Moderate Maternal Stress? 2Health News:Interactive Video, Better Teaching Aid For Toddlers 2Health News:In-Vivo Gene Therapy Technique to Cure XSCID in Basset Pups 2Health News:In-Vivo Gene Therapy Technique to Cure XSCID in Basset Pups 3Health News:PAI-2 Plays a Pivotal Role in Eye Infections 2Health News:Discovery Of New Molecule Could Solve Cancer Spread Mystery 2
(Date:7/11/2014)... LONDON , July 11, 2014 /PRNewswire/ ... of visitors to Safety & Health Expo ... by the move to London ... senior management attending exhibition.     ... (Photo: http://photos.prnewswire.com/prnh/20140711/696892-a ) ...
(Date:7/10/2014)... , 11. Juli 2014 /PRNewswire/ ... Kameras für die molekulare Bildgebung, einschließlich ... heute die CE-Zulassung für sein Navigator ... kann Dilon das Produkt jetzt europaweit ... den Großteil der europäischen Länder ausgedehnt ...
(Date:7/10/2014)... , July 10, 2014 Integrated Silicon ... in advanced memory and analog IC solutions, today announced ... Thursday, July 24, 2014, at 7:00 a.m. Pacific Time ... results for the fiscal 2014 third quarter ended June ... via telephone, dial 1-888-556-4997 before 6:50 a.m. Pacific time ...
Breaking Medicine Technology:UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2
... TOX/See™ is a 1-step, hand-held, point-of-care device ... metabolites in human urine. The TOX/See device ... commonly abused drugs in 3 to 8 minutes ... Each TOX/See cassette is individually packaged to maximize ...
... The Carpal Solution offers relief from CTS ... is different from other over-the-counter CTS treatments. ... Worn during sleep, the Carpal Solution gently ... Carpal Tunnel and eliminates hand pain, numbness ...
... Linearity is a whole blood formulation ... range of the most popular glucose ... of using a control matrix that ... is packaged in ready-to-use dropper vials ...
... ESR-10 Manual Rack is a manual ... the erythrocyte sedimentation rate (ESR) of ... 1.2ml Streck ESR-Vacuum Tubes. The rack ... simultaneously. The ESR-10 Manual Rack exhibits ...
Medicine Products: