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Bad Enzymes Found To Enable Brain Recovery Following Stroke

ee days following stroke. Extensive brain damage was seen when the inhibitor was given at 7 or 14 days after stroke.

Surprisingly, high levels of the MMPs were found adjacent to the damaged area, more specifically in the peri-infarct cortex, an area that enables recovery of the brain following stoke.

'We have mostly thought of MMPs as being bad. Our data strongly suggest that they play a totally different role during stroke recovery. The peri-infarct zone is very dynamic and potentially very malleable for long periods of time after stroke,' said Eng H. Lo, from the Neuroprotection Research Laboratory at Massachusetts General Hospital.

The researchers have however warned about the use of these compounds in stroke management, as the activity of the MMPs has to be regulated to ensure an optimal recovery of the stroke patient.


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