Navigation Links
Bacteria Harnessed as Micro-Robot Motors

Normally we want to avoid having bacteria in our eyes, urethras, and spinal columns, but researchers at Carnegie Mellon University would like to change that.// They have figured out how to glue S. marcescens to micro-robots for the delivery of drugs to hard to reach areas of the body.

One of the main challenges in developing microscale robots lies in miniaturising their power and propulsion. Now, researchers in the US may have found a solution to this problem, by exploiting the natural movement of bacteria to propel micro-objects through water.

Many bacteria propel themselves along in a fluid by rotating their corkscrew-like tails, called flagella, at relatively high speeds. These flagella are only around 20 nanometres in diameter and are about 10,000 nm long.

Motors made from bacterial flagella have been used as novel "nano-actuators" before, but Metin Sitti and Bahareh Behkam of Carnegie Mellon University in Pennsylvania, US, have taken another approach. They use the entire microorganism as the motor and control its on/off motion with chemicals.

Sitti and Behkam began by sticking several S. marcescens - the kind of bacteria that cause pink stains on shower curtains - onto polystyrene beads 10 microns in diameter. These tiny "robots" were suspended in a solution containing water and glucose.

The bacteria themselves are only about one-fifth of the size of each bead and adhere to them via electrostatic, van der Waals forces and hydrophobic interactions. As the attached bacteria rotate their flagella, feeding on surrounding glucose, they push their bead forward at speeds of around 15 microns per second.

To stop the bacteria's motion, the researchers add copper sulphate to the solution. The copper ions bond to the rotor of the flagella motor and prevent it from moving. To restart the motion, another chemical called ethylenediaminetetraacetic acid (EDTA) is added. The EDTA traps the copper ions attached to th e rotor, allowing it to move again. The rotors can be switched off in this way an unlimited number of times.

Using the entire microorganism as a motor has many advantages, the researchers say. Bacteria are robust machines that can easily be integrated with other microscopic components and do not need to be purified or reconstituted, as detached bacterial components must be.

Moreover, the bacteria motors work using simple nutrients such as glucose and are naturally sensitive to their environment. This means they can be precisely controlled.

"In the future, such hybrid swimming micro-robots could even be used to deliver drugs inside the liquid environments of the human body, such as the urinary tract, eyeball cavity, ear and cerebrospinal fluid," Sitti told New Scientist. "They could also be employed to monitor toxic or pathogenic biochemical agents in the environment as well for inspection and maintenance of liquid filled pipes in spacecraft and nuclear plants."

Source-Bio-Bio Technology
SRI
'"/>




Related medicine news :

1. Bacterial discovery may help CF patients
2. Cure for Bacterial Meningitis
3. Before Weight Loss Surgery One Should Get Tested for Bacteria
4. Molecule That Aids Bacterial Infections Identified
5. Moms Stomach Bacteria Can Cause Leukaemia In Children
6. Bacteria Evolve Armamentarium Against Antibiotics By ‘Stealing’ Gens
7. Bacterial Photographs Created By Student Scientists!
8. Bacterial infestation in food very critical!
9. Tooth Decay Bacteria Unaffected By Altered Biochemical Pathway
10. Beneficial Symbiotic Relationship Between Ants And Bacteria.
11. Tamiflu substrate produced from Bioengineered Bacteria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... June 23, 2017 , ... By scoring 100% for ... consecutive four-star rating from premier online charity evaluator, Charity Navigator, validating ANRF's work as ... of all charities reviewed by Charity Navigator and earns ANRF a spot on their ...
(Date:6/23/2017)... ... 2017 , ... Dr. Ran Y. Rubinstein , a ... offering three new minimally invasive procedures to patients who want a younger and ... Rubinstein is excited to bring microneedling, microneedling facials, and platelet rich plasma (PRP) ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Aesthetic Channel has recently highlighted ... has come up with a proprietary technique that he calls the AuraLyft ... dropped. For all ages, patients can expect to look refreshed, rejuvenated, and revitalized. ...
(Date:6/23/2017)... ... June 23, 2017 , ... MD Now Urgent Care ... MD Now’s 28th facility overall and marks the urgent care center's eighth location in ... North of The Falls shopping mall. The new clinic offers a wide array of ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ulster University, Magee Campus in Northern Ireland is ... 3 pm to present to graduate students exciting new and innovative hope research based ... led by The Health Improvement Service of the Western Health & Social Care Trust ...
Breaking Medicine News(10 mins):
(Date:6/9/2017)... , June 9, 2017 More than 400 ... effort to help spread lessons learned from clinical research ... Diabetes Federation (IDF) and Eli Lilly and Company (NYSE: ... second phase of the Bringing Research in Diabetes to ... commitment to helping people with diabetes effectively manage their ...
(Date:6/7/2017)... 7, 2017 Endo International plc (NASDAQ: ... the Hon. Joseph R. Goodwin , U.S. District ... West Virginia , entered a case management order ... System Products Liability Litigation (the "MDL") that includes a ... provide expert disclosures on specific causation within one hundred ...
(Date:6/5/2017)... , June 5, 2017 Kohll,s Pharmacy & Homecare is ... the United States . The Raizer is a ... fallen person up to an almost-standing position within ... operated by one assistant and does not require ... enough that a child can operate it, and ...
Breaking Medicine Technology: