Navigation Links
Bacteria Harnessed as Micro-Robot Motors

Normally we want to avoid having bacteria in our eyes, urethras, and spinal columns, but researchers at Carnegie Mellon University would like to change that.// They have figured out how to glue S. marcescens to micro-robots for the delivery of drugs to hard to reach areas of the body.

One of the main challenges in developing microscale robots lies in miniaturising their power and propulsion. Now, researchers in the US may have found a solution to this problem, by exploiting the natural movement of bacteria to propel micro-objects through water.

Many bacteria propel themselves along in a fluid by rotating their corkscrew-like tails, called flagella, at relatively high speeds. These flagella are only around 20 nanometres in diameter and are about 10,000 nm long.

Motors made from bacterial flagella have been used as novel "nano-actuators" before, but Metin Sitti and Bahareh Behkam of Carnegie Mellon University in Pennsylvania, US, have taken another approach. They use the entire microorganism as the motor and control its on/off motion with chemicals.

Sitti and Behkam began by sticking several S. marcescens - the kind of bacteria that cause pink stains on shower curtains - onto polystyrene beads 10 microns in diameter. These tiny "robots" were suspended in a solution containing water and glucose.

The bacteria themselves are only about one-fifth of the size of each bead and adhere to them via electrostatic, van der Waals forces and hydrophobic interactions. As the attached bacteria rotate their flagella, feeding on surrounding glucose, they push their bead forward at speeds of around 15 microns per second.

To stop the bacteria's motion, the researchers add copper sulphate to the solution. The copper ions bond to the rotor of the flagella motor and prevent it from moving. To restart the motion, another chemical called ethylenediaminetetraacetic acid (EDTA) is added. The EDTA traps the copper ions attached to th e rotor, allowing it to move again. The rotors can be switched off in this way an unlimited number of times.

Using the entire microorganism as a motor has many advantages, the researchers say. Bacteria are robust machines that can easily be integrated with other microscopic components and do not need to be purified or reconstituted, as detached bacterial components must be.

Moreover, the bacteria motors work using simple nutrients such as glucose and are naturally sensitive to their environment. This means they can be precisely controlled.

"In the future, such hybrid swimming micro-robots could even be used to deliver drugs inside the liquid environments of the human body, such as the urinary tract, eyeball cavity, ear and cerebrospinal fluid," Sitti told New Scientist. "They could also be employed to monitor toxic or pathogenic biochemical agents in the environment as well for inspection and maintenance of liquid filled pipes in spacecraft and nuclear plants."

Source-Bio-Bio Technology
SRI
'"/>




Related medicine news :

1. Bacterial discovery may help CF patients
2. Cure for Bacterial Meningitis
3. Before Weight Loss Surgery One Should Get Tested for Bacteria
4. Molecule That Aids Bacterial Infections Identified
5. Moms Stomach Bacteria Can Cause Leukaemia In Children
6. Bacteria Evolve Armamentarium Against Antibiotics By ‘Stealing’ Gens
7. Bacterial Photographs Created By Student Scientists!
8. Bacterial infestation in food very critical!
9. Tooth Decay Bacteria Unaffected By Altered Biochemical Pathway
10. Beneficial Symbiotic Relationship Between Ants And Bacteria.
11. Tamiflu substrate produced from Bioengineered Bacteria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... ... 2016 , ... Since launching its annual volunteer campaign on ... footwear industry, has broken all previous participation records in its first two weeks ... during the months of April and May, the 2016 Footwear Cares initiative is ...
(Date:4/29/2016)... ... 29, 2016 , ... Shamangelic Healing, Sedona Arizona's Premier ... Alpha BRAIN and New Mood Daily-Stress Formula for brain optimization and wellness to ... the store is just one more way Shamangelic Healing supports people’s quest for ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... On Tuesday, ... hospitals across the Southeast, celebrated the signature of Gov. Nathan Deal on SB 258, ... Geoff Duncan (R - Cumming), offers a 70% tax credit to individuals and corporations ...
(Date:4/29/2016)... ... April 29, 2016 , ... Dr. ... of best seller "LOVE, MEDICINE and MIRACLES") addresses touchy topics related to Death ... podcasted thereafter . Dr. Bernie Siegel, author of a plethora of essential ...
(Date:4/29/2016)... ... April 29, 2016 , ... Conditions were ideal for Global ... Park on Sunday, with sunny skies, a light breeze and temperatures in the 60s. ... , The 5k Run and Walk and 1-mile walk were held to increase ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016 , Net Sales of $1.90 billion ... the prior year period, and an increase of 1.2% on ... EPS for the first quarter were $0.52 reported, a decrease ... an increase of 29.9% over the prior year period ... guidance for 2016 Zimmer Biomet Holdings, Inc. (NYSE ...
(Date:4/28/2016)... N.J. , April 28, 2016   Acsis ... today announced that leading IT market research and advisory ... " in the IDC MarketScape: Worldwide Pharmaceutical Track and ... 2016).  The report provides an assessment of the capabilities ... track and trace software market. Logo - ...
(Date:4/28/2016)... 28, 2016 New market ... is a report that provides an overview of ... pipelines by identifying new targets and MOAs to ... Profiles discussed in this H1 2016 Osteoarthritis Pipeline ... AbbVie Inc., Abiogen Pharma S.p.A., Ablynx NV, Achelios ...
Breaking Medicine Technology: