Navigation Links
Bacteria Harnessed as Micro-Robot Motors

Normally we want to avoid having bacteria in our eyes, urethras, and spinal columns, but researchers at Carnegie Mellon University would like to change that.// They have figured out how to glue S. marcescens to micro-robots for the delivery of drugs to hard to reach areas of the body.

One of the main challenges in developing microscale robots lies in miniaturising their power and propulsion. Now, researchers in the US may have found a solution to this problem, by exploiting the natural movement of bacteria to propel micro-objects through water.

Many bacteria propel themselves along in a fluid by rotating their corkscrew-like tails, called flagella, at relatively high speeds. These flagella are only around 20 nanometres in diameter and are about 10,000 nm long.

Motors made from bacterial flagella have been used as novel "nano-actuators" before, but Metin Sitti and Bahareh Behkam of Carnegie Mellon University in Pennsylvania, US, have taken another approach. They use the entire microorganism as the motor and control its on/off motion with chemicals.

Sitti and Behkam began by sticking several S. marcescens - the kind of bacteria that cause pink stains on shower curtains - onto polystyrene beads 10 microns in diameter. These tiny "robots" were suspended in a solution containing water and glucose.

The bacteria themselves are only about one-fifth of the size of each bead and adhere to them via electrostatic, van der Waals forces and hydrophobic interactions. As the attached bacteria rotate their flagella, feeding on surrounding glucose, they push their bead forward at speeds of around 15 microns per second.

To stop the bacteria's motion, the researchers add copper sulphate to the solution. The copper ions bond to the rotor of the flagella motor and prevent it from moving. To restart the motion, another chemical called ethylenediaminetetraacetic acid (EDTA) is added. The EDTA traps the copper ions attached to th e rotor, allowing it to move again. The rotors can be switched off in this way an unlimited number of times.

Using the entire microorganism as a motor has many advantages, the researchers say. Bacteria are robust machines that can easily be integrated with other microscopic components and do not need to be purified or reconstituted, as detached bacterial components must be.

Moreover, the bacteria motors work using simple nutrients such as glucose and are naturally sensitive to their environment. This means they can be precisely controlled.

"In the future, such hybrid swimming micro-robots could even be used to deliver drugs inside the liquid environments of the human body, such as the urinary tract, eyeball cavity, ear and cerebrospinal fluid," Sitti told New Scientist. "They could also be employed to monitor toxic or pathogenic biochemical agents in the environment as well for inspection and maintenance of liquid filled pipes in spacecraft and nuclear plants."

Source-Bio-Bio Technology
SRI
'"/>




Related medicine news :

1. Bacterial discovery may help CF patients
2. Cure for Bacterial Meningitis
3. Before Weight Loss Surgery One Should Get Tested for Bacteria
4. Molecule That Aids Bacterial Infections Identified
5. Moms Stomach Bacteria Can Cause Leukaemia In Children
6. Bacteria Evolve Armamentarium Against Antibiotics By ‘Stealing’ Gens
7. Bacterial Photographs Created By Student Scientists!
8. Bacterial infestation in food very critical!
9. Tooth Decay Bacteria Unaffected By Altered Biochemical Pathway
10. Beneficial Symbiotic Relationship Between Ants And Bacteria.
11. Tamiflu substrate produced from Bioengineered Bacteria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified ... be personalized through a fitness app. The fitness app plans to fix the two major ... only offer a one size fits all type program , They don’t eliminate ...
(Date:6/25/2016)... Miami, FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton ... Plant City Observer , brings up a new, often overlooked aspect of head lice: ... The closing for fumigation is not a common occurrence, but a necessary one in the ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... Those ... deal with these feelings, many turn to unhealthy avenues, such as drug or alcohol ... of Marne, Michigan, has released tools for healthy coping following a traumatic event. , ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg ... Legal Elite. The attorneys chosen by their peers for this recognition are considered among ... Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite Hall ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Ontario , June 27, 2016  VMS Rehab ... Company,s Board will take whatever measures required to build ... Company,s stock which is currently listed on the OTC ... Wexler, Company Chairman and CEO, "We are seeing an ... difficult to understand, not only by the Company, but ...
(Date:6/24/2016)... , June 24, 2016  Global Blood Therapeutics, ... company developing novel therapeutics for the treatment of ... announced the closing of its previously announced underwritten ... at the public offering price of $18.75 per ... were offered by GBT. GBT estimates net proceeds ...
(Date:6/24/2016)... The Academy of Managed Care Pharmacy (AMCP) ... would allow biopharmaceutical companies to more easily share health ... and coverage decisions, a move that addresses the growing ... The recommendations address restrictions in the sharing of ... label, a prohibition that hinders decision makers from accessing ...
Breaking Medicine Technology: