Navigation Links
BCG vaccine to be boosted to effectively prevent tuberculosis

Tuberculosis remains a major global health threat. One method of reducing the incidence of the disease is to vaccinate the person with the so called BCG vaccine. // Although more than 3 billion doses of the BCG vaccine have been administered to fight tuberculosis, the ability of the BCG vaccine to protect adults is very limited. This has led us to ponder over the effectiveness of the vaccine in preventing the disease. A new strategy to enhance the immunogenicity of BCG has been suggested by researchers. In addition they have described a novel vaccine strain with high efficacy against tuberculosis. The researchers have engineered a BCG strain that secretes a protein called listeriolysin, which punches holes in the membranes of phagosomes where M. tuberculosis is located, allowing better T cell-mediated immunity. The new form of the vaccine is active at a pH of 5.8, and thereby eliminating the need for utilizing the urease C gene of BCG that normally plays a role in pH neutralization of the phagosome. The lack of urease C allows phagosomal acidification and provides an ideal pH environment for listeriolysin. The new BCG vaccine strain has been found to protect mice against tuberculosis significantly better than the parental BCG. Superior protection is not only induced against the laboratory strain of M. tuberculosis but also against a clinical isolate of the Beijing/W family, a strain of tuberculosis that is spreading all over the world, is drug-resistant, and is responsible for the most threatening disease outbreaks.
'"/>




Page: 1

Related medicine news :

1. New hope for cancer victims – will vaccine cure the deadly bug
2. New vaccine helps allergy and asthma patients
3. Man against HIV – new vaccine ready for human trials
4. New vaccine helps allergy and asthma patients
5. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
6. HIV did not arise from polio vaccine
7. Double impact vaccine
8. High Demand for a child vaccine
9. A new vaccine for leukemia
10. Shortage of MMR vaccine
11. Anthrax vaccine produced
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: BCG vaccine boosted effectively prevent tuberculosis

(Date:7/13/2014)... research in Nature Genetics identifies a ... that causes eosinophillic esophagitis (EoE), opening up potential ... food allergy. , EoE is a chronic ... triggered by allergic hypersensitivity to certain foods and ... cells called eosinophils (part of the body,s immune ...
(Date:7/13/2014)... Chromatography system is a physical method of separation ... samples such as air and water. Chromatography systems ... namely mobile phase and stationary phase. The components ... phase, followed by the differential rate of migration ... mixture. Chromatography system plays an important role in ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Victorian Hotel ... by promoting the rental of bikes for its "Cycle ... downtown Victorian Hotel to tour the area using a ... tax. Bicycle enthusiasts love to call Vancouver home, as ... for cycle travel and picturesque journeys through the countryside. ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Micro irrigation ... ensure proper water dispersal as wells as to maintain ... agriculture is projected to become a dominant revenue generator ... sophisticated methods to reduce resource costs has led to ... and plantations, and has further caused massive demand for ...
(Date:7/13/2014)... 13, 2014 Advanced boilers are ... least amount of fossil fuels, produce high-capacity power, ... to increased global warming and climate change concerns, ... reduce harmful gas emissions and pollutants coming from ... in the global advance boilers market., The global ...
Breaking Medicine News(10 mins):Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 2Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 3Health News:North America Chromatography Systems Market Is Expected to Reach $6593.4 Million by 2018 - New Report by MicroMarket Monitor 2Health News:North America Chromatography Systems Market Is Expected to Reach $6593.4 Million by 2018 - New Report by MicroMarket Monitor 3Health News:Victorian Hotel Creates Excitement by Adding "Cycle the City" Bike Rentals for Its Vancouver Hotel Rooms 2Health News:Agricultural Micro Irrigation System Market is Expected to Grow at a CAGR of 18.1%, from 2013 to 2018 - New Report by MicroMarket Monitor 2Health News:Agricultural Micro Irrigation System Market is Expected to Grow at a CAGR of 18.1%, from 2013 to 2018 - New Report by MicroMarket Monitor 3Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 2Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 3
... MATEO, Calif., Feb. 28 NeurogesX, Inc.,(Nasdaq: ... and,commercializing novel pain management therapies, announced today that,Anthony ... to a,panel focused on pain management at Susquehanna ... Conference. Mr. DiTonno,is scheduled to present on Tuesday, ...
... latest technologies and ... medical advancements, AUSTIN, Texas, ... hospital, officially opened the expansion of its,heart hospital today with the ... rated as the number one overall,cardiac program in the State of ...
... diagnose severity of bipolar illness , , THURSDAY, Feb. 28 ... mood disorders have been identified by Indiana University School ... the way bipolar illness is diagnosed and treated. , ... found varying levels of the biomarkers in participants with ...
... (TSX: MDS; NYSE:,MDZ), a leading provider of products ... that the Company will report first quarter,results for ... will also host an analyst conference call with ... Douglas Prince,Executive Vice-President Finance and Chief Financial Officer, ...
... to $977.3mm for Full Year; Up 27% to $268.0mm for ... Fourth Quarter, - Adjusted EPS (incl. Stock Compensation) Up ... for Fourth Quarter (GAAP EPS ... up 62% to $0.47), - Continuing New Win Momentum and Pipeline Strengthening Across Segments, - ...
... 28 Cardiva Medical, Inc., a,privately held medical ... announces that it will present the highlights of ... 9:20am at the Medtech,Insight/Windhover Information,s "Investment In Innovation ... at The,Venetian in Las Vegas, NV., The ...
Cached Medicine News:Health News:NeurogesX to Present at Susquehanna Financial Group's 2nd Annual SIGnificant Options in Healthcare Conference 2Health News:NeurogesX to Present at Susquehanna Financial Group's 2nd Annual SIGnificant Options in Healthcare Conference 3Health News:Heart Hospital of Austin's Expansion Increases Patient Capacity by 30 Percent 2Health News:Heart Hospital of Austin's Expansion Increases Patient Capacity by 30 Percent 3Health News:Heart Hospital of Austin's Expansion Increases Patient Capacity by 30 Percent 4Health News:Biomarkers for Mood May Alter Psychiatric Treatments 2Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 2Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 3Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 4Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 5Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 6Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 7Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 8Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 9Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 10Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 11Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 12Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 13Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 14Health News:inVentiv Health Reports Record Financial Results for Fourth Quarter and Full Year 2007 15Health News:Cardiva Medical, Inc. to Present Highlights of the Boomerang Catalyst(TM) II System at the 'Investment in Innovation (In3) West' Conference on February 29, 2008 in Las Vegas, NV 2
(Date:7/11/2014)... , July 11, 2014 ... "Scintillator Market by Composition of Material, Application (Healthcare, ... others), End Product (Personal Instrument, Hand-Held Instruments, Fixed, ... and Analysis to 2013 - 2020", published by MarketsandMarkets, the ... CAGR of 5.62% from 2014 to 2020, and ...
(Date:7/11/2014)... 2014  Australian drug delivery company, Phosphagenics Limited (ASX: ... A$19.3 million via a placement of A$16.3 million to ... U.S., Asia and ... purchase plan (SPP) to be offered to existing shareholders. ... two tranches. "This capital raising positions us ...
(Date:7/11/2014)... , July 11, 2014 Research and ... of the "Immunoprotein Diagnostic Testing Market - ... highest CAGR of 6% and is expected to ... to their offering. ... diagnostic testing has been segmented according to immunoprotein ...
Breaking Medicine Technology:Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2
... for individuals living with West Nile Virus and ... or immune compromised, PURCHASE, N.Y., Sept. 9 ... State University supported by the Division of,Vector-Borne Infectious ... (CDC) has demonstrated that AHCC(R) (Active Hexose Correlated,Compound) ...
... SAN DIEGO, Sept. 9 Ardea Biosciences, Inc.,(Nasdaq: ... presented on,the Company,s lead mitogen-activated ERK kinase (MEK) inhibitor, ... at,the Gaylord Palms Resort & Convention Center in Orlando., ... follows:, Date/Time: Tuesday, October 7, 2008 from 10:30 ...
Cached Medicine Technology:Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus 2Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus 3Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at American College of Gastroenterology Annual Scientific Meeting 2
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
Medicine Products: