Navigation Links
Avicena to Advance Huntington's Disease Clinical Program into Phase III

Avicena Group, Inc. (OTC Bulletin Board: AVGO), a late stage biotechnology company that develops central nervous system therapeutics for neurodegenerative diseases, announced today the selection of the optimal dose of HD-02, its novel drug candidate for the treatment of Huntington's Disease.

This dose was determined in an open-label dose escalation study, led by Dr. Steven Hersch and Dr. Diana Rosas of Massachusetts General Hospital (MGH), and will be further evaluated in a Phase III clinical trial.

The dose escalation study evaluated HD-02 in a range of doses from 10 to 40 grams per day and successfully determined the optimal dose that provided the maximum efficacy, safety and tolerability. The full scope of the data will be disseminated upon the results being peer reviewed.

Based on these findings, Avicena and its collaborators Dr. Hersch and the Huntington Study Group have developed a double-blind, placebo-controlled Phase III clinical trial anticipated to commence in early 2008. The Phase III trial will be one of the single largest trials for Huntington's patients, with external funding to be announced.

Upon commencement of this clinical trial, Avicena will have advanced three different indications into phase III trials that include some of the largest trial to date in both Parkinson's and Huntington's.

"We are very encouraged by the results of our HD-02 trial and we believe that in conjunction with our collaborators at MGH, we have identified the optimal dose as we move forward to validate HD-02 as a potential treatment for Huntington's disease, for which there is no current approved drug by the FDA.

We are committed to developing therapeutics that we hope can slow the progression of neurodegenerative diseases," stated Belinda Tsao-Nivaggioli, CEO of Avicena.

"We are excited by the results of our studies with HD-02 to date. This Phase III study will evaluat
'"/>




Page: 1 2

Related medicine news :

1. Advances in Treatment of Cataracts
2. Advanced STD programs required
3. Hope For Patients With Advanced Breast Cancer
4. Advances In Stem Cells Research
5. Breast Cancer Advance
6. Canadian Lung Cancer Study Lauded As Major Advance in Cancer Fight
7. Speedier Access To Advances In Breast Cancer Sought For Patients
8. HIV Vaccine Field Trials In Advanced Stage
9. Advance Funeral For AIDS-infected South African
10. New Screening Techniques to Lead Advances In Pain Therapy
11. Twin Treatment Could Be Used Increase Survival Rates In Advanced Melanoma
Post Your Comments:
(Date:12/24/2014)... (PRWEB) December 24, 2014 Connie Casad, ... and functional medicine advocate with 30 years of practice ... to evaluate the health benefits of dietary detoxification. The ... new participants following excellent results from test patients who ... asked to explain her interest in conducting the study, ...
(Date:12/24/2014)... 24, 2014 The federal court ... the blood thinner caused life-threatening episodes of internal ... structure for the proceeding, Bernstein Liebhard LLP reports. ... Court plans to select lawyers to serve as ... on appointing a Plaintiffs’ Steering Committee, which will ...
(Date:12/24/2014)... 2014 BambooIndustry.com a famous bamboo flooring ... Today, the company announces its multiple layer bamboo ... on these new products. , Bamboo panel is the ... multiple layer bamboo panel board features high quality selective ... emissions free. The bamboo panel consists of multiple layers ...
(Date:12/24/2014)... 2014 (HealthDay News) -- Adults who experienced childhood ... migraine headaches, suggests a study published online Dec. ... "Childhood maltreatment can have long-lasting effects, like associated ... study author Dawn Buse, director of behavioral medicine ... said in a journal news release. "When ...
(Date:12/24/2014)... 24, 2014 Gluten, a protein found ... who have an intolerance to gluten, causing side effects ... migraine headaches, joint pain and fatigue. For this reason, ... that deliver safe and fast weight loss while ... a gluten allergy reaction. These gluten free diet plans ...
Breaking Medicine News(10 mins):Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 2Health News:Connie Casad, MD, Now Accepting Test Participants for January Dietary Detoxification Study 3Health News:Court Overseeing Federal Xarelto Lawsuits Issues Coordination Order, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal Xarelto Lawsuits Issues Coordination Order, Bernstein Liebhard LLP Reports 3Health News:Bamboo Flooring Company Bambooindustry.com Introduces Its Multiple Layer Bamboo Panel Board Collection 2Health News:Abuse in Childhood Tied to Migraines in Adulthood 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 3
... , PITTSBURGH, Sept. 22 Precision Therapeutics today ... received the Smart Business Magazine 2009 Pacesetters Award. This ... area who are setting the pace for the region. ... of their influence in the community-at-large as well as within ...
... , , ... CutisPharma, Inc. announced the introduction of FIRST(R) - BXN Mouthwash. ... line, which already includes FIRST(R) - Mouthwash BLM. The active ... in the most routinely prepared formulation of Magic Mouthwash containing Benadryl(R), ...
... , , AUSTIN, ... pleased to announce its selection to participate in DEMO conference,s ... features the "coolest, earliest-stage companies." Ringful will launch a mobile ... mobile phone into a connected personal healthcare dashboard, resulting in ...
... Twin ... for 10-city whirlwind tour of Japan to change hearts and minds about the benefits ... , ... (PRWEB) September 22, 2009 -- Twin Triumph Productions, LLC announced today that Academy Award ...
... ATLANTA, Sept. 22 Atlanta Falcons Defensive End Chauncey ... Follmer and Camp Kudzu- Georgia,s largest camp for kids with ... Blank Family Office. , , Davis was ... and Jonathan Babineaux, corporate executives and community leaders during the ...
... research is too focused on new drug development, while not ... advances in knowledge likely to have the biggest impact on ... research policy expert says, adding that a major shift in ... with the coming wave of cancer cases. Professor Richard ...
Cached Medicine News:Health News:Precision Therapeutics President and CEO Sean McDonald Recipient of 2009 Pacesetters Award 2Health News:CutisPharma Launches New Prescription Mouthwash Kit Adding to Product Line 2Health News:Ringful Selected for DEMO's AlphaPitch; Launching PreventiveCare.mobi Healthcare Application Suite 2Health News:Twin Triumph Productions and 'The Power of Two' Go to Japan 2Health News:Twin Triumph Productions and 'The Power of Two' Go to Japan 3Health News:Atlanta Falcons Chauncey Davis Honors 2009 Community Impact Awardees 2Health News:Expert calls for new cancer research priorities 2Health News:Expert calls for new cancer research priorities 3
(Date:12/24/2014)... Dec. 23, 2014 ResMed (NYSE: RMD ... action against Chinese medical device manufacturer BMC Medical Co., Ltd. ... that BMC,s masks listed below infringe ResMed,s patents, and entered ... masks in the United States : ... mask , Willow nasal pillows mask , iVolve ...
(Date:12/24/2014)... Dec. 23, 2014  Lockton Dunning Benefits, the ... Companies, announced the addition of Vice President ... Lockton Dunning,s Pharmacy Consulting team, Excelsior Solutions. ... industry experience to the position.  Most recently, she ... at Diplomat Specialty Pharmacy, where she has held ...
(Date:12/24/2014)... RALEIGH, N.C. , Dec. 23, 2014 ... plc (NASDAQ: ENDP ) (TSX: ENL), and ... announced today that they have submitted a New Drug ... U.S. Food and Drug Administration (FDA).  Buprenorphine HCl Buccal ... severe enough to require daily, around-the-clock, long-term opioid treatment ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2Kim Foerster Joins Lockton Companies 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 4Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 5
... 1, 2012  Ultragenyx Pharmaceutical Inc., a biotechnology company ... genetic disorders, today announced results from a first-in-human, ... with hereditary inclusion body myopathy (HIBM) showing that ... profile on absorption after oral administration.  UX001 is ...
... (OTC Bulletin Board: NWBO ) (NW Bio) today announced ... received approval of a major grant from the Sachsische Aufbau ... will reimburse fifty percent (50%) of the costs for manufacturing ... for brain cancer at up to ...
Cached Medicine Technology:Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease 2Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease 3Northwest Bio Awarded $5.5 Million German Government Grant 2Northwest Bio Awarded $5.5 Million German Government Grant 3Northwest Bio Awarded $5.5 Million German Government Grant 4
... The new HF35-50 High Frequency Ultrasound ... high resolution, high frequency system available. The ... ultrasound biomicroscopy of the anterior segment with ... posterior segment ultrasound with a 20 MHz ...
... portable, digital A-scan system which provides easy-to-use ... high frequency, low noise probe and fast ... application of the probe along the visual ... display, storage of 5 different user profiles, ...
... Accurate, efficient and easy to use. The ... variety of regressive, theoretical, and adaptive IOL ... the patient. Convenient design features improve your ... hands-free operation, audible tone to minimize corneal ...
... In addition to three conventional measurement modes ... also incorporates a new axial length measuring ... by calculating sonic velocity for conversion at ... length by calculating each tissues sonic velocity ...
Medicine Products: