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Autism Case Hearing Still to Produce Clinching Evidence on Vaccine Linkage

so under cross-examination, Aposhian said that he was not an immunologist and that he had composed his theory of thimerosal-induced immunological damage "three or four weeks ago." When government attorney Vincent Matanoski tried to get Aposhian to acknowledge that most if not all cases of clinical mercury poisoning in the past had involved doses hundreds or thousands of times higher than what was administered to children in vaccines, the toxicologist insisted that dose was not necessarily important.

When the mercury was administered, and his or her genetic susceptibility were more relevant issues, he argued. In order to win their case, it seems likely that Cedillos will have to convince the three special masters -- the judges, in effect, in the special "vaccine court" at the U.S. Court of Claims -- of the reliability of the witnesses' account that measles RNA was detected in her bowel and cerebrospinal fluid.

RNA is a nucleic acid found in all living cells and it is this complex compound that controls cellular function and heredity. A biopsy from Michelle Cedillo's gastrointestinal trct was sent in 2003 to Unigenetics, an Irish laboratory headed by Dr. John O'Leary, which reported finding the RNA. O'Leary and his colleagues had published a paper a year earlier that disclosed the discovery of measles RNA in the guts of several autistic children.

The lab also was said to have found evidence of measles in spinal taps of autistic children, but those results were never published. Last year, two journal articles reported an inability to replicate the O'Leary lab's findings. An expert report commissioned by a British court has found problems in Unigenetics' testing of the samples.

In testimony that followed Aposhian this past week, five additional witnesses for Cedillo expressed full support for the Unigenetics findings. Those witnesses were gastroenterologist Arthur Krigsman, molecular biologist Karin Hepner, immun
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