Navigation Links
Atypical Antibiotics For Super Bugs

Researchers from the Notre Dame University have developed unusual antibiotics that have the potential to be effective against the super bugs. The research findings were presented at the 230th national meeting of the American Chemical Society, the world’s largest scientific society. //

The new antibiotics are synthetic forms of cephalosporin, a broad-spectrum antibiotic closely related to penicillin. They appear to kill bacteria by masquerading as components of the bacterial cell wall in order to deactivate an enzyme that functions as a key bacterial defense mechanism, the researchers say. In preliminary lab tests, the new antibiotics — the first to exhibit this mimicry mechanism — were effective against vancomycin-resistant MRSA, a rare but extremely deadly staph strain for which treatment options are extremely limited, they say.

Besides fighting staph bacteria, the compounds have the potential to work against a wide range of other types of infectious bacterial strains that appear in health-care and community settings, he says. At least one of the cephalosporin compounds identified has entered Phase I clinical trials (human studies), but results are not yet available.

Researchers had recently discovered, in a study published in the February issue of the Journal of the American Chemical Society, that the enzyme interacts with certain components of the bacterial cell wall and that targeting these components might deactivate the enzyme, making the bacteria vulnerable to attack. Subsequently, the group identified a set of three novel cephalosporin antibiotics that appear to interact with the enzyme and also contain protein components that are similar to those of the bacterial cell wall.

More studies are needed to verify the details of this unique mechanism and to determine whether other antibiotics use this mechanism. So far, only three antibiotics — all of them cephalosporin derivatives — appear to function by this mimicry mechanism.

Source: Newswise
'"/>




Related medicine news :

1. Atypical Lobular Hyperplasia increases risk of breast cancer
2. No Evidence to Support Many Off-label Uses of Atypical Antipsychotics
3. Antibiotics Dangerous for Diarrhoea in Children Caused by E.Coli
4. Antibiotics Helps Autism
5. Antibiotics losing their power against acne
6. Antibiotics help heart patients
7. Antibiotics May Help Prevent Strokes
8. Antibiotics Found To Increase The Risk Of Developing Breast Cancer
9. Antibiotics Overload For Kids Questioned
10. The Use Of Antibiotics Questioned
11. The Dangers Of Prescribing Antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... ... 26, 2017 , ... Amir Qureshi, MD is the first physician in Arkansas ... stimulation system. The Nuvectra™ Algovita SCS System has been FDA approved as a treatment ... in Arkansas to introduce the most powerful SCS system and the only stretchable lead ...
(Date:5/26/2017)... ... May 26, 2017 , ... On May 24, the ... narrowly passed the U.S. House on May 4, would result in 23 million Americans ... continued implementation of the 2010 Patient Protection and Affordable Care Act (ACA). , ...
(Date:5/26/2017)... ... May 26, 2017 , ... Dr. Alex Rabinovich, a ... announce a new, informational blog post on insurance options. If a Bay Area patient ... may help save time and money. Visiting an in-network provider for a second opinion ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “Cactus Jack: Against ... on so many others. “Cactus Jack: Against All Odds” is the creation of ... Walter D. Hubbard is married to Jack Carlisle’s third child Jane. Walter. Walter ...
(Date:5/24/2017)... Hills, CA (PRWEB) , ... May 24, 2017 , ... ... announced today its participation in nVerge 2017 – a one-day technology conference in San ... Altec’s document management solution, which allows users to fully utilize and enhance their Sage ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... 10, 2017  The Corporate Whistleblower Center says, ... sleep therapy clinics to call us anytime at ... is involved in a substantial scheme to overbill ... from an employee of a medical equipment company ... to provide medical practice groups with extra generous incentives ...
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals ... ), a clinical-stage pharmaceutical company focused on the ... that the Canadian Intellectual Property Office has granted ... Oral Administration of Exenatide". The patent covers Oramed,s ... GLP-1 is an incretin hormone that ...
(Date:5/6/2017)... , May 5, 2017  May is Stroke ... one of the most important methods to prevent a ... the Centers for Disease Control and Prevention, undetected and ... 1 Omron, the global leader in personal heart ... the elimination of heart attack and stroke and is ...
Breaking Medicine Technology: