Navigation Links
Atypical Antibiotics For Super Bugs

Researchers from the Notre Dame University have developed unusual antibiotics that have the potential to be effective against the super bugs. The research findings were presented at the 230th national meeting of the American Chemical Society, the world’s largest scientific society. //

The new antibiotics are synthetic forms of cephalosporin, a broad-spectrum antibiotic closely related to penicillin. They appear to kill bacteria by masquerading as components of the bacterial cell wall in order to deactivate an enzyme that functions as a key bacterial defense mechanism, the researchers say. In preliminary lab tests, the new antibiotics — the first to exhibit this mimicry mechanism — were effective against vancomycin-resistant MRSA, a rare but extremely deadly staph strain for which treatment options are extremely limited, they say.

Besides fighting staph bacteria, the compounds have the potential to work against a wide range of other types of infectious bacterial strains that appear in health-care and community settings, he says. At least one of the cephalosporin compounds identified has entered Phase I clinical trials (human studies), but results are not yet available.

Researchers had recently discovered, in a study published in the February issue of the Journal of the American Chemical Society, that the enzyme interacts with certain components of the bacterial cell wall and that targeting these components might deactivate the enzyme, making the bacteria vulnerable to attack. Subsequently, the group identified a set of three novel cephalosporin antibiotics that appear to interact with the enzyme and also contain protein components that are similar to those of the bacterial cell wall.

More studies are needed to verify the details of this unique mechanism and to determine whether other antibiotics use this mechanism. So far, only three antibiotics — all of them cephalosporin derivatives — appear to function by this
'"/>




Page: 1 2

Related medicine news :

1. Atypical Lobular Hyperplasia increases risk of breast cancer
2. No Evidence to Support Many Off-label Uses of Atypical Antipsychotics
3. Antibiotics Dangerous for Diarrhoea in Children Caused by E.Coli
4. Antibiotics Helps Autism
5. Antibiotics losing their power against acne
6. Antibiotics help heart patients
7. Antibiotics May Help Prevent Strokes
8. Antibiotics Found To Increase The Risk Of Developing Breast Cancer
9. Antibiotics Overload For Kids Questioned
10. The Use Of Antibiotics Questioned
11. The Dangers Of Prescribing Antibiotics
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Atypical Antibiotics For Super Bugs

(Date:1/22/2015)... Yesterday, Senator Holly Mitchell (D-Los ... Olsen (R-Modesto) were honored by the California Healthcare ... biomedical science, medical device and pharmaceutical innovation in ... “2014 Life Sciences Champion” award from CHI President ...
(Date:1/22/2015)... Four years since the release of their debut recording Love ... of Avasa & Matthew Love – the duo are pleased to ... through White Swan Records on February 24, 2015. , THE ROAD ... available to all of us to walk out of the mire ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 As interest in ... health care gains momentum worldwide, Rev. Eric J. Hall ... Chaplaincy Network (HCCN), will be the keynote speaker on ... in Israel’s public health system. , The conference, “Hope and ...
(Date:1/22/2015)... 2015 Lower-Auto-Insurance.com has released a new blog post ... car for reducing the costs of an auto insurance policy ... able to get lower prices for their vehicle insurance policies. The ... in determining policy costs. Because of this, drivers should always ...
(Date:12/26/2014)... December 26, 2014 The US represents the ... report. In 2013, GlobalData’s forecast estimates that sales of branded ... market due to the high incidence of the disease, high ... 5EU, Japan, and China. Increased sales of CRC therapies over ...
Breaking Medicine News(10 mins):Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 2Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 3Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 4
... particles for treatment of diseases. ‘Nano’ refers to billionth ... for treatment of fatal diseases, which will help to ... to develop Nanotechnology in the next 10 years which ... diabetes, Cancer, HIV infection, Alzheimer’s and Parkinson’s diseases. Six ...
... at UCLA had found out the peptides that ward ... more than 20 years ago at UCLA, defensins are ... ward off viruses. However, it was unclear how defensins ... a specific defensin called retrocyclin-2 (RC2) binds to carbohydrate-containing ...
... no sunscreen in spite of staying under direct sunlight for ... spend a significant amount of time practicing and competing in ... are spending so much time in the sun, they have ... them regularly use any form of sunscreen, according to a ...
... that are difficult to handle. Even when so much has ... viral infection has always been a problem. Viral infections ... the disease-causing virus has always been potent enough to escape ... Human Immunodeficiency Virus as it is called has been posing ...
... Immunization (IFFIm) will be providing life saving vaccines for ... project costing $4 billion to be funded by the ... the scheme, the International Finance Facility for Immunization (IFF), ... over the next 10 years and another five million ...
... and Rabia Khatoon's joy knew no bounds when they got ... to pay for the surgery to separate their conjoined twins.// ... thousands of miles away has offered to help us,' Khatoon, ... even as the children get medical attention at New Delhi's ...
Cached Medicine News:Health News:Nanotechnology Revolution To Be Spearheaded By European Union 2Health News:People Still Neglect To Use Sunscreen In Spite Of Cancer Warnings 2Health News:European Countries To Fund $4 Billion For Vaccination For Poor Children’ 2Health News:When A Prince Chose To Help Indian Couple 2
(Date:1/23/2015)... baseball,s all-time hits leader, is the new spokesperson for the ... has announced. "Pete,s a Hall of Famer in ... board with Myoflex," said Ducere Pharma Chief Executive Officer ... known across all generations. The passion and intensity that Pete ...
(Date:1/23/2015)... , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. (OTCQB: LIXT), ... I trial of Lixte,s lead compound, LB‑100, is being conducted, ... John S. Kovach , M.D., the founder and President ... be completed at a single site. Accrual of patients, however, ...
(Date:1/23/2015)... (NYSE: MNK ) announced today that its ... The open-ended authorization permits the company to repurchase up ... "Funding additional initiatives and seeking attractive business ... pursue a range of focused growth strategies," said ...
Breaking Medicine Technology:Pete Rose bets on Myoflex to relieve aches and pains 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... DURECT Corporation (Nasdaq: DRRX ) announced today that it has secured a ... million of its registered common stock to Azimuth Opportunity Ltd. for a ... $50 million facility.  DURECT did not pay a commitment fee or ... , , ...
... WASHINGTON , July 1 Hanger Orthopedic ... efforts in response to the January 12th ... alliance of U.S.-based international development and humanitarian nongovernmental organizations. ... Orthopedic Group was nominated by Physicians for Peace, an ...
Cached Medicine Technology:DURECT Corporation Secures $50 Million Committed Equity Financing Facility 2DURECT Corporation Secures $50 Million Committed Equity Financing Facility 3Hanger Orthopedic Group Honored for its Charitable Relief Efforts in Haiti by InterAction 2Hanger Orthopedic Group Honored for its Charitable Relief Efforts in Haiti by InterAction 3
... 20-year history, the VOYAGER RX Dilatation Catheter ... outcomes. It combines a new low profile, ... shaft,more flexible markers, and short taper balloon ... tortuous anatomy with even greater confidence, opening ...
... Guidants 20-year history, the VOYAGER RX Dilatation ... treatment outcomes. It combines a new low ... profile shaft,more flexible markers, and short taper ... and tortuous anatomy with even greater confidence, ...
... Coat-A-Count AFP IRMA,is an ... measurement of,alpha-fetoprotein (AFP) in serum. ... vitro use in either of,two ... aid in the,management of patients ...
Enzyme immunoassay for the quantitative determination of ovarian cancer antigen CA125 in human serum...
Medicine Products: