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Atherosclerosis and its Mechanics

s now working to understand how both stretching and shear forces influence JNK activation.

"We still need to limit the amount of cholesterol in our diet, especially the low-density lipoprotein, or bad cholesterol," said Chien. "But our new understanding of how mechanical forces affect JNK will eventually help us gain better understanding of the mechanism underlying the focal localization of atherosclerotic lesions and design better approaches to treat this important disease state."

(Eurekalert)
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