Navigation Links
Astrocytes Found To Cause Epilepsy

Study carried out by Professor. Maiken Nedergaard and his Colleagues at the University of Rochester Medical center, Newyork has found that Astrocytes has been found to be involved in the initiation and propogation of epileptic discharges // , which was published in Nature Medicine.

Epilepsy occurs when the brain chemical, glutamate, stimulates neurons to act in an uncontrolable way leading to seizures or loss of consciousness. Most of the research has been focussed on the brain cells and not in the neurons and this new study will open new avenuses for the pharmacological treatment of epilepsy. Neurologists generally believe that epilepsy causes the production of abnormal cells called reactive astrocytes – oversized, bloated, star-shaped cells that no longer function properly in their “housekeeping” role of maintaining the brain’s optimum chemical environment.

Astrocytes are a major type of brain cell, but because they are not involved in electrical activity within the brain, they have been studied relatively little. The cell type is found in larger proportion - and with more “points” on the star-shaped cell - in animals with higher brain function. Monkeys have roughly the same number of astrocytes as neurons in their brains, whereas humans have 10 times as many astrocytes as neurons. Recently, more has been discovered about the importance of these cells and the role they play in diseases, from stroke to Alzheimer’s.

Donald Weave, president of Epilepsy Canada, agrees. The role of glial cells, the cells that surround and support neurons, in epilepsy and neurology "has been understudied", he says. "We have been hammering away at the same old approaches for years and so a new way in with astrocyte involvement would be very useful."

Professor Nedergaard said, “To our great surprise, we found that there was an increase in reactive astrocytes in all five models, which could not have been caused by over-firing of the neurons as exp ected – because there had been no neural firing,” “And the reactive astrocytes were producing excessive glutamate in the rats. It turns out that reactive astrocytes trigger epilepsy, and not the other way around.”

Source: The NewScientist
'"/>




Related medicine news :

1. Link between Astrocytes and Alzheimers Discovered
2. Fluoride Found Effective in Osteoporosis
3. Implantable Contact Lens Found Safe and Effective
4. Cancer hazard Found With Animal-Based Nutrients
5. Processed Meat, Diabetes connection Found
6. Night Time Aspirin Regimen Found to Reduce Blood Pressure
7. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
8. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
9. Preventive Therapies Found to be More Effective in Managing Migraines
10. Common Cold Found to Fight Cancer
11. Circumcision Found To Prevent HIV Spread
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... More than ... Hep B United Philadelphia, and the Prevent Cancer Foundation held an event on National ... epidemic in the city of viral hepatitis, the leading cause of liver cancer. , ...
(Date:5/31/2016)... ... 2016 , ... St. Joseph Medical Center (SJMC) announced that ... enables physicians at SJMC’s two hospital campuses, downtown and in the Heights, to ... exchange. SJMC’s membership in the health information exchange underscores the hospital’s commitment to ...
(Date:5/31/2016)... ... May 31, 2016 , ... When MetLoop first demonstrated its ... something that contractors should have at their disposal on a daily basis. , ... Director of Contractor Programs. , As a result, Metloop and CertainTeed entered ...
(Date:5/31/2016)... ... May 31, 2016 , ... Spartan Bioscience ... enables unprecedented portability and convenience. , The Cube is exceptionally small—it takes up ... the Cube fits easily into any space, whether in a hospital, doctor’s office, ...
(Date:5/31/2016)... ... ... Like jewels in a crown, the multiple awards presented to Fayez Spa confirm ... day spa and one of Canada’s few accredited 5 Star Spas! , The ... spa services with hair and beauty services and has resulted in creating ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... , May 31, 2016 Aloe ... in food, cosmetics and pharmaceuticals, with global volume to ... US$ 1.6 Bn. Demand for aloe vera ... and yogurts will continue its upward momentum in 2016 ... also boost positive sentiment on aloe vera, with wide-ranging ...
(Date:5/31/2016)... Israel , May 31, 2016 ... its proprietary plant-based rhCollagen technology for tissue repair products ... Chief Scientist of Israel,s Ministry ... 12 million development project for 2016. The Chief Scientist,s grant ... year,s authorized grant, which totaled NIS 4.7 million.  ...
(Date:5/31/2016)... , May 31, 2016 ... research report with comparative analysis of Asthma therapy at ... action (MoA), route of administration (RoA) and molecule type, ... releases. It also reviews key players involved in the ... and discontinued projects. Complete report on H1 ...
Breaking Medicine Technology: