Navigation Links
Astrocytes Found To Cause Epilepsy

Study carried out by Professor. Maiken Nedergaard and his Colleagues at the University of Rochester Medical center, Newyork has found that Astrocytes has been found to be involved in the initiation and propogation of epileptic discharges // , which was published in Nature Medicine.

Epilepsy occurs when the brain chemical, glutamate, stimulates neurons to act in an uncontrolable way leading to seizures or loss of consciousness. Most of the research has been focussed on the brain cells and not in the neurons and this new study will open new avenuses for the pharmacological treatment of epilepsy. Neurologists generally believe that epilepsy causes the production of abnormal cells called reactive astrocytes – oversized, bloated, star-shaped cells that no longer function properly in their “housekeeping” role of maintaining the brain’s optimum chemical environment.

Astrocytes are a major type of brain cell, but because they are not involved in electrical activity within the brain, they have been studied relatively little. The cell type is found in larger proportion - and with more “points” on the star-shaped cell - in animals with higher brain function. Monkeys have roughly the same number of astrocytes as neurons in their brains, whereas humans have 10 times as many astrocytes as neurons. Recently, more has been discovered about the importance of these cells and the role they play in diseases, from stroke to Alzheimer’s.

Donald Weave, president of Epilepsy Canada, agrees. The role of glial cells, the cells that surround and support neurons, in epilepsy and neurology "has been understudied", he says. "We have been hammering away at the same old approaches for years and so a new way in with astrocyte involvement would be very useful."

Professor Nedergaard said, “To our great surprise, we found that there was an increase in reactive astrocytes in all five models, which could not have been caused by over-firing of the neurons as exp ected – because there had been no neural firing,” “And the reactive astrocytes were producing excessive glutamate in the rats. It turns out that reactive astrocytes trigger epilepsy, and not the other way around.”

Source: The NewScientist
'"/>




Related medicine news :

1. Link between Astrocytes and Alzheimers Discovered
2. Fluoride Found Effective in Osteoporosis
3. Implantable Contact Lens Found Safe and Effective
4. Cancer hazard Found With Animal-Based Nutrients
5. Processed Meat, Diabetes connection Found
6. Night Time Aspirin Regimen Found to Reduce Blood Pressure
7. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
8. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
9. Preventive Therapies Found to be More Effective in Managing Migraines
10. Common Cold Found to Fight Cancer
11. Circumcision Found To Prevent HIV Spread
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... June 26, 2016 , ... ... they have been diagnosed with endometriosis. These women need a treatment plan to ... a comprehensive approach that can help for preservation of fertility and ultimately achieving ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, ... the latter, setting the bar too high can result in disappointment, perhaps even self-loathing. ... toward their goal. , Research from PsychTests.com reveals that behind the ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
Breaking Medicine Technology: