Navigation Links
Astrocytes Found To Cause Epilepsy

Study carried out by Professor. Maiken Nedergaard and his Colleagues at the University of Rochester Medical center, Newyork has found that Astrocytes has been found to be involved in the initiation and propogation of epileptic discharges // , which was published in Nature Medicine.

Epilepsy occurs when the brain chemical, glutamate, stimulates neurons to act in an uncontrolable way leading to seizures or loss of consciousness. Most of the research has been focussed on the brain cells and not in the neurons and this new study will open new avenuses for the pharmacological treatment of epilepsy. Neurologists generally believe that epilepsy causes the production of abnormal cells called reactive astrocytes – oversized, bloated, star-shaped cells that no longer function properly in their “housekeeping” role of maintaining the brain’s optimum chemical environment.

Astrocytes are a major type of brain cell, but because they are not involved in electrical activity within the brain, they have been studied relatively little. The cell type is found in larger proportion - and with more “points” on the star-shaped cell - in animals with higher brain function. Monkeys have roughly the same number of astrocytes as neurons in their brains, whereas humans have 10 times as many astrocytes as neurons. Recently, more has been discovered about the importance of these cells and the role they play in diseases, from stroke to Alzheimer’s.

Donald Weave, president of Epilepsy Canada, agrees. The role of glial cells, the cells that surround and support neurons, in epilepsy and neurology "has been understudied", he says. "We have been hammering away at the same old approaches for years and so a new way in with astrocyte involvement would be very useful."

Professor Nedergaard said, “To our great surprise, we found that there was an increase in reactive astrocytes in all five models, which could not have been caused by over-firing of the neurons as exp ected – because there had been no neural firing,” “And the reactive astrocytes were producing excessive glutamate in the rats. It turns out that reactive astrocytes trigger epilepsy, and not the other way around.”

Source: The NewScientist
'"/>




Related medicine news :

1. Link between Astrocytes and Alzheimers Discovered
2. Fluoride Found Effective in Osteoporosis
3. Implantable Contact Lens Found Safe and Effective
4. Cancer hazard Found With Animal-Based Nutrients
5. Processed Meat, Diabetes connection Found
6. Night Time Aspirin Regimen Found to Reduce Blood Pressure
7. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
8. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
9. Preventive Therapies Found to be More Effective in Managing Migraines
10. Common Cold Found to Fight Cancer
11. Circumcision Found To Prevent HIV Spread
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its first-ever ... Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding work ... Practice and Pediatric Emergency Medicine Practice. , “With this award, we recognize ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital ... area economy by obtaining investment capital for emerging technology companies. SCP has ... have already resulted in more than a million dollars of capital investment for ...
(Date:6/24/2016)... Gaithersburg, MD (PRWEB) , ... June 24, 2016 ... ... and protocols for human induced pluripotent stem (iPS) cells and other difficult to ... PluriQ™ G9™ Cloning Medium. The PluriQ™ G9™ Gene Editing System is ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... and infrastructure. Most providers, however, are unsure how to move forward, given the ... to define a path forward tailored to an organization’s specific needs. , PYA ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today ... Inc.,s Supplier Horizon Award . One ... Guerbet was recognized for its support of Premier members ... through clinical excellence, and commitment to lower costs. ... receive this recognition of our outstanding customer service from ...
(Date:6/23/2016)... , June 23, 2016  Experian ... integrating and transforming the patient payment and ... several innovative new products and services that ... its revenue cycle offerings. These award-winning solutions ... efficient workflows, remain compliant in an ever-changing ...
(Date:6/23/2016)... 2016 Leading BioSciences Inc., a clinical-stage ... resulting from a breakdown of the mucosal barrier, ... Doyle as chief executive officer. Mr. Doyle, ... team and board of directors, previously served as ... will provide continued leadership and strategic direction to ...
Breaking Medicine Technology: