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Astrazeneca's Investigational Cancer Therapies Revealed at ASCO

ression may be delayed.Preclinical studies have identified AZD0530 as a selective inhibitor of Src activity. In the study data presented today, biomarkers confirmed inhibition of Src in human cancers for the first time.Principal Investigator for the study(1) presented today at ASCO, Jose Baselga MD, Chairman and Professor of Medicine, Vall d'Hebron University Hospital, Barcelona, Spain commented, "The AZD0530 clinical trial program was exceptionally well-designed allowing full evaluation of the optimal methodology for measuring Src activation prior measuring its inhibition by AZD0530.

By collecting as much information early on in our clinical trials we give ourselves the best chance of identifying those patients who could benefit most from treatment with AZD0530 in the future."About AstraZenecaAstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services.

It is one of the world's leading pharmaceutical companies with healthcare sales of $26.47 billion and leading positions in sales of gastrointestinal, cardiovascular, neuroscience, respiratory, oncology and infection products. AstraZeneca is listed in the Dow Jones Sustainability Index (Global) as well as the FTSE4Good Index.In the United States, AstraZeneca is a $12.44 billion healthcare business with more than 12,000 employees.

For nearly three decades, AstraZeneca has offered drug assistance programs side by side with its medicines, and over the past five years, has provided over $3 billion in savings to more than 1 million patients throughout the US and Puerto Rico. AstraZeneca has been named one of the "100 Best Companies for Working Mothers" by Working Mother magazine and is the only large pharmaceutical company named to FORTUNE magazine's 2007 list of "100 Best Companies to Work For." In 2006, for the fifth consecutive year, Science magazine
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