Navigation Links
Aspirin and other NSAIDS Proved Less Effective in Long-Term Smokers

An increased risk of colorectal cancer has been found among long-term smokers – a large-scale study reports.Researchers at Fred Hutchinson// Cancer Research Center have demonstrated that a lower protective effect of anti-inflammatory drugs such as NSAIDS and aspirin has been noticed among colorectal cancer patients, who are long-term smokers.

In a large, population-based study comparing risk factors in people with and without colorectal cancer, the researchers found the highest risk of colon cancer to be among long-term smokers of 20 or more years who had never used NSAIDs. The researchers also found that smokers who used NSAIDs were still at an approximate 30 percent higher risk of colon cancer than nonsmokers.

The findings, which appear in the July 1 issue of Cancer Research, arise from the first study of its kind to examine the effects of NSAID use on colorectal-cancer risk among smokers, said first author Victoria Chia, a research associate in the Hutchinson Center's Cancer Prevention Program.

‘Smoking has been linked to a modestly increased risk of colorectal cancer, and use of NSAIDs has been shown to significantly decrease the risk of colorectal cancer. We wanted to see if NSAIDs could counteract the adverse effects of smoking with regard to colorectal-cancer risk, and whether these associations differed by tumor characteristics,’ she said.

In particular, Chia and colleagues were interested in examining the impact of NSAIDs on a certain type of colorectal tumor that may be associated with smoking. Such tumors display microsatellite instability, an acquired genetic characteristic that indicates defects in DNA-repair machinery. Microsatellite instability, or MSI, occurs in approximately 15 percent to 20 percent of colon cancers.

The researchers found a two-fold increased risk of microsatellite-unstable colorectal tumors among long-term smokers who took NSAIDs -- about the same risk as smokers who had not used NS
'"/>




Page: 1 2

Related medicine news :

1. What happens when Asthmatics consume Aspirin?
2. Aspirin reduces deaths
3. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
4. Aspirin - a drug after one’s own hear
5. Aspirin deflated
6. Aspirin surpasses Modern Anti-clotting Drugs
7. Night Time Aspirin Regimen Found to Reduce Blood Pressure
8. Aspirin Lowers Leukemia Risk
9. Aspirin usage linked with pancreatic cancer
10. Aspirin Found To Reduce The Risk Of Colon Cancer
11. Aspirin Induced Asthma , A Little-Known Inducer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Aspirin and other NSAIDS Proved Less Effective Long Term Smokers

(Date:9/30/2014)... 30, 2014 Speaking on this occasion, ... observed ‘Nursing Conference’ as a remarkable event, which brings ... medical and clinical research and diagnostic companies, leading universities ... a perfect platform to share experience, foster collaborations across ... world. Nursing Conference is a forum to explore issues ...
(Date:9/30/2014)... New Zealand (PRWEB) September 30, 2014 ... the potential to improve breast cancer risk prediction ... according to a study published in Breast Cancer ... “Digital mammographic density and breast cancer risk: a ... demonstrates a strong connection between breast density and ...
(Date:9/30/2014)... and its partners successfully established a visual mapping ... myeloid derived suppressor cells (MDSC). The damage and ... understood, however this is a major stepping stone ... by tumor-derived factors from precursors present in hematopoietic ... spleen. This population of cells suppresses the activity ...
(Date:9/30/2014)... A recent study completed at the University of Eastern ... the risk of coronary heart disease. The sources of ... The findings were published in Arteriosclerosis, Thrombosis & ... Heart Association. , Recent studies have not found an ... risk of cardiovascular diseases. It seems that the mere ...
(Date:9/30/2014)... 2014 This two-day, advanced PT ... sequellae that may arise following a concussion or ... can be varied, from sports related injuries, car accidents, ... by the thousands of returning soldiers from war zone ... and blunt traumas can result in similar injuries, the ...
Breaking Medicine News(10 mins):Health News:Exploring New Possibilities to Take Nursing Profession to Great Heights 2Health News:Exploring New Possibilities to Take Nursing Profession to Great Heights 3Health News:Mammographic Density Offers Potential to Improve Prediction of Breast Cancer Risk and Development of Personalized Screening 2Health News:Mammographic Density Offers Potential to Improve Prediction of Breast Cancer Risk and Development of Personalized Screening 3Health News:Mammographic Density Offers Potential to Improve Prediction of Breast Cancer Risk and Development of Personalized Screening 4Health News:Dietary polyunsaturated fatty acids linked to smaller risk of coronary heart disease 2Health News:North American Seminars Presents Traumatic Brain Injury and Concussions in Conduction with St. Anthony's Medical Center in St. Louis, MO on November 8-9, 2014 2Health News:North American Seminars Presents Traumatic Brain Injury and Concussions in Conduction with St. Anthony's Medical Center in St. Louis, MO on November 8-9, 2014 3
... Minn. People with a particular gene variant may be more ... people without the gene, according to a study published in the ... journal of the American Academy of Neurology. , The ... no cancers. All those with tumors had glioblastoma multiforme, the most ...
... when they spend any timeeven a few monthswithout health care ... 2009 issue of Medical Care Research and Review . ... four months, there is a 2.8 percentage point decrease in ... the study, Partial-Year Insurance Coverage and the Health Care Utilization ...
... other experts sponsor workshop to investigate increase in Acanthamoeba ... contact lens care products and protect against infectionsST. LOUIS, ... safety and effectiveness of contact lenses and lens care ... Optometric Association (AOA) co-sponsored a workshop last week with ...
... of batches tested positive, third of popular sweetened products ... Almost half of tested samples of commercial high-fructose corn ... nearly a third of 55 popular brand-name food and ... labeled ingredient, according to two new U.S. studies. , ...
... AFL ) announced today that it will release ... 2, 2009. , In conjunction ... meeting on Tuesday, February 3, 2009. During the ... discuss Aflac,s fourth,quarter and year-end results. Following Mr. Amos, ...
... of cases, study finds , , MONDAY, Jan. 26 ... the United States are more likely than girls ... at football, soccer, volleyball, basketball, wrestling, baseball and ... 8 percent of all injuries suffered by high ...
Cached Medicine News:Health News:New study: Short coverage lapses limit children's access to health care services 2Health News:AOA Doctors of Optometry Partner With FDA and Other Industry Leaders to Develop New Measures to Better Protect Contact Lens Wearers 2Health News:AOA Doctors of Optometry Partner With FDA and Other Industry Leaders to Develop New Measures to Better Protect Contact Lens Wearers 3Health News:AOA Doctors of Optometry Partner With FDA and Other Industry Leaders to Develop New Measures to Better Protect Contact Lens Wearers 4Health News:AOA Doctors of Optometry Partner With FDA and Other Industry Leaders to Develop New Measures to Better Protect Contact Lens Wearers 5Health News:Study Finds High-Fructose Corn Syrup Contains Mercury 2Health News:Aflac Incorporated To Release Fourth Quarter Results on February 2, 2009 2Health News:HS Sports Shoulder Injuries More Likely in Boys 2
(Date:9/30/2014)... , Sept. 30, 2014 Headquartered in ... GWPC) is a diversified company comprised of several specialized ... advanced technology and the proven expertise of its team ... and wellness. WholeHealth Products, line of more than 10 ... centers, and its more than 8 retail consumer tests ...
(Date:9/30/2014)... N.Y. , Sept. 30, 2014  Millennium ... Millennium Medical Devices, has executed a sales, marketing ... Florida based provider of ... Accountable Care Organizations (ACOs) and hospitals through a ... serves over 10,400 active Physician Purchasing Accounts that ...
(Date:9/30/2014)...  The Corporate Whistleblower Center is urging ER ... 866-714-6466 if they have well documented proof of ... been sent home, as an intentional way to ... as the Center would like to explain. ... Photo - http://photos.prnewswire.com/prnh/20140929/149017 ...
Breaking Medicine Technology:WholeHealth Products Announces The Discovery Of The "Autism And Fragile X" Microwell And Rapid Diagnostic Test 2Millennium Healthcare Secures New Sales, Marketing and Distribution Agreement 2Millennium Healthcare Secures New Sales, Marketing and Distribution Agreement 3Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 2Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 3Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 4
... 16 The board of directors of Intarcia Therapeutics, ... Kurt Graves as executive chairman of the board. In ... leadership to the board and work closely with management ... development with its potential blockbuster asset, ITCA 650 (DUROS® ...
... ONXX ) today announced that it will present ... 22, 2010 at 3:00 p.m. Eastern Time (12:00 p.m. Pacific ... of the presentation on our website at: ... on 15 minutes early in order to register and download ...
Cached Medicine Technology:Intarcia Therapeutics Names Kurt Graves Executive Chairman to Advance Strategic Interests and Broaden Commercial Goals 2Intarcia Therapeutics Names Kurt Graves Executive Chairman to Advance Strategic Interests and Broaden Commercial Goals 3Onyx Pharmaceuticals to Present at the UBS Global Life Sciences Conference 2
This adjustable-volume digital micropipet is used to accurately measure and transfer small solution volumes in the 20-200 microliter range....
... and density. Proven ergonomic design reduces hand fatigue, prevents injury. Dry seal ... 20-200 ... 1.0~2.0 Imprecision(%) ... 1 Dimensions: ...
This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,411-9) or contact custom...
Pipetman P is a fully adjustable, air-displacement pipette with the selected volume shown on a digital indicator (volumeter). Eight models cover the full range of volumes from 0.2 L to 10 mL....
Medicine Products: