Navigation Links
Aspirin Might Counter Side Effects of Cox-2 Painkillers

After the failure of Vioxx, pain killer which was found to cause the death of Robert C. Ernst on May 2001 after taking Vioxx. Merck Pharma the manufacturers of Vioxx were asked by the Texas Jury to pay $253.5 million as compensation // to Mrs. Ernst. Over 5 years, about 20 million people worldwide took Vioxx before Merck stopped selling the drug in September 2004, after a clinical trial found irrefutable evidence that Vioxx had heart risks compared with a placebo.

Due to the high toxic and side effects of pain killers like Vioxx, the researchers were in search of pain killers with no toxic effects and they found that the Age old still world wide used Aspirin was found to have no toxicity in addition it was found to decrease the incidence of heart attacks. The study was conducted by Dr. Thomas Coffman, Chief of Nephrology at Duke University. The findings of the research which was published in Cell metabolism has shown that the painkillers like Vioxx are strong Cox-2 inhibitors which interferes with the chemical pathways that causes pain.

v Though Cox-2 inhibitors have good effect in reducing pain, they may cause high blood pressure and severe cardiovascular problems. These drugs inhibit both the hormones responsible for both widening and narrowing of the blood vessels and this causes blood to form dangerous clots. Contrast to Cox-2 inhibitors, aspirin helps in blood thinning which is good for blood circulation. Though the research success as occurred in genetically modified mice model the scientists as to go for a clinical trial in order to test the efficacy of the drug in humans. The cardiovascular protection of the aspirin drug has to be tested in Cox-2 inhibitor drug users. The recruit for the study has to be taking Cox-2 drugs for some time and they should be given aspirin and compared with the placebo and Cox-2 drug user groups.


'"/>




Page: 1

Related medicine news :

1. What happens when Asthmatics consume Aspirin?
2. Aspirin reduces deaths
3. Aspirin and Warfarin Are Equally Effective for Stroke Prevention
4. Aspirin - a drug after one’s own hear
5. Aspirin deflated
6. Aspirin surpasses Modern Anti-clotting Drugs
7. Night Time Aspirin Regimen Found to Reduce Blood Pressure
8. Aspirin Lowers Leukemia Risk
9. Aspirin usage linked with pancreatic cancer
10. Aspirin Found To Reduce The Risk Of Colon Cancer
11. Aspirin Induced Asthma , A Little-Known Inducer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/10/2016)... ... February 10, 2016 , ... Intermedix ... of Emergency Medicine , an emergency medicine professional association, to support the organization's ... , The American Academy of Emergency Medicine, or AAEM, seeks to empower emergency ...
(Date:2/10/2016)... , ... February 10, 2016 , ... Emergency rooms provide ... to find. Unfortunately, this can leave patients with dental emergencies at risk of losing ... now offering emergency dental care. , Common dental emergencies include:, ...
(Date:2/10/2016)... ... February 10, 2016 , ... Dr. Jessica Barron, of ... is now accepting new dental patients and families in the North Metro Denver area. ... services from cleanings to cosmetic dentistry, and all in the most relaxing environment. , ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... organization, welcomes S.S. Nesbitt as the latest addition to its growing list of ... other locations throughout the Southeast, from Orlando to Huntsville and in between. , ...
(Date:2/10/2016)... ... , ... Armune BioScience signed a definitive agreement with ARCpoint ... across the country. Launched in April of 2015, Apifiny is the only cancer specific, ... order volume exceeded 3,000 tests in 2015. Primary care physicians and urologists have utilized ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... LONDON , February 10, 2016 A new report ... 2021 - states that the Alzheimer,s disease market will more than double ... 2021, at a Compound Annual Growth Rate (CAGR) of 11%. ... Italy , Spain , the UK, and ... prevalence during the forecast period. --> Canada , ...
(Date:2/10/2016)... SAN DIEGO , Feb. 10, 2016 ... viral gene therapy manufacturing, and Renova™ Therapeutics, a biopharmaceutical ... and other chronic diseases, have entered into a Manufacturing ... produce cGMP-grade RT-100 (Ad5.hAC6) Drug Product for use in ... --> This relationship will leverage Lonza,s ...
(Date:2/10/2016)... , Feb. 10, 2016 Immune Pharmaceuticals Inc. ... announced today that it has filed a patent application ... other cancers. --> --> ... by administration of Ceplene (histamine dihydrochloride) in combination with ... of predicting the efficacy of Ceplene and IL-2 therapy ...
Breaking Medicine Technology: