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Aspartame, Artificial Sweetener, A Safe Bet!

The long raging debate over the safety of artificial sweeteners got an impetus when a new study confirms. The Calorie Control Council today stated that a rat study conducted by Italy’s Ramazzini Institute //is totally contradictory with the extensive scientific research and regulatory reviews conducted on aspartame. The U.S. Food & Drug Administration (FDA) has said they are not recommending any changes in the use of aspartame. The study, to be published in Environmental Health Perspectives, a publication of the National Institute of Environmental and Health Sciences (NIEHS), alleges that aspartame may be related to an increased risk of leukemia and lymphoma in rats. The design and execution of the study did not follow guidelines set up by the National Toxicology Program (NTP), the U.S. government toxicology initiative administered by the NIEHS.

NTP has recently completed three animal studies designed to evaluate whether aspartame is capable of causing cancer. These U.S. government funded and managed studies were conducted using Good Laboratory Practice (GLP) and the results were peer-reviewed by individuals considered experts in their profession. The results of these cancer studies, in which aspartame was fed at levels similar to those reportedly fed in the Ramazzini study, unequivocally indicated that “there was no evidence of carcinogenic activity [cancer] of aspartame.”

Previous findings by the Ramazzini researchers at the same institution using a similar protocol have been reviewed by the FDA’s Cancer Assessment Committee, which noted that those reported data were “unreliable” due to a “lack of critical details … and … questionable histopathological conclusions… .” The aspartame findings from the Ramazzini researchers recently were reviewed by the expert United Kingdom Committee on Carcinogenicity of Chemicals in Food, Consumer Products and the Environment. Members of that Committee characterized aspects of study findings as “implausible,”
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