Navigation Links
Appetite Changes, Depression Signal Impulse Control Disorders in Parkinson

Parkinson disease patients who develop impulse control disorders as a result of treatment are more likely to be depressed, irritable, and have appetite changes, according// to a study published in the October 10, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology. These findings could allow early identification of patients at risk for developing this distressing complication of treatment.

Compulsive gambling, hypersexuality, and excessive shopping have been linked to treatment with dopamine agonists in small numbers of patients. It is unknown exactly how many patients experience such an impulse control disorder, although it is believed to be less than 10 percent of those receiving these drugs.

To identify risk factors for development of impulse control disorder, the authors studied 100 Parkinson disease patients, including 66 men and 34 women, who were receiving the full range of standard anti-Parkinson medications, including levodopa, dopamine agonists, and other drugs. They administered a standard battery of psychiatric tests to identify the presence of depression, anxiety, delusions, and other psychiatric conditions, as well as impulse control disorder.

They found that nine of the 100 patients had an impulse control disorder, including four with pathological gambling, two with hypersexuality, one with excessive shopping, and two with both hypersexuality and excessive shopping. All nine were receiving a dopamine agonist, in addition to other medications.

Compared to patients without an impulse control disorder, patients with one were more than twice as likely to have depressive symptoms, were more than three times as likely to have appetite changes, and were more than six times as likely to have symptoms of irritability and disinhibition.

“These results highlight the potential usefulness of depression and appetite changes as ‘sentinel symptoms’ associated with an impulse control disorder,” according to lead study author Laura Marsh, MD, with Johns Hopkins University School of Medicine in Baltimore, Maryland, and a member of the American Academy of Neurology. “Since only a small fraction of patients receiving dopamine agonists develop this disorder, these findings may help identify those most at risk. Strategies for treatment may include changing medications or avoiding situations that may lead to the impulsive behavior.”


Related medicine news :

1. The Reason For Loss Of Appetite After Gastric Bypass
2. Stomach Hormone to Aid in Controlling Appetite
3. Study Highlights Appetite Regulation Pathway, New Hope for Weight Loss
4. Brain behind the Brawn: Vital Molecule in the Brain Controls Appetite
5. Study Confirms That Slow Eating Restricts Appetite
6. Estrogen Curbs Appetite: Research
7. Estrogen Curbs Appetite In Same Way as the Hormone Leptin
8. Mitochondrial Protein Maintains Appetite During Fasting
9. Role of Appetite Hormone MCH in Insulin Production Revealed
10. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
11. Depression may cause delayed wound healing
Post Your Comments:

(Date:11/25/2015)... ... ... “While riding the bus, I saw a passenger in a wheelchair drenched from ... a convenient and comfortable way to protect them from bad weather, so I invented ... during cold or inclement weather. In doing so, it ensures that the user remains ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible for advancing care ... disease. The Periwinkle Pioneers, nominated by the public, will receive special recognition throughout ...
(Date:11/25/2015)... ... November 25, 2015 , ... An unlikely combination ... in a way for homeless people to have a more dignified and comfortable ... initiative whereby they are repurposing plastic bags into sleeping mats for the homeless. ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... focused on providing comprehensive solutions involving adult stem cell therapies to patients with ... deemed the “Regenestem” name as a Registered Trademark (RTM). , Organizations are required ...
(Date:11/24/2015)... ... 2015 , ... Genesis Chiropractic Software helps practice owners automate ... between the practice owner and the patient that automatically manages all five aspects ... Click here to learn more. , According to Dr. Brian ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , November 25, 2015 Kitov ... ) (TASE: KTOV), a biopharmaceutical company focused on the ... various clinical conditions, today announced the closing of its ... Shares ( ADSs ), each representing 20 ordinary shares ... 3,158,900 ADSs. The ADSs and warrants were issued in ...
(Date:11/25/2015)... , Nov. 25, 2015 Allergan ... pharmaceutical company, and Rugen Therapeutics, a start-up  biotechnology ... for unmet CNS disorders and funded by the ... they have entered into an exclusive collaboration to ... for Autism Spectrum Disorders (ASD) and Obsessive Compulsive ...
(Date:11/25/2015)... Israel , November 25, 2015 ... "New Investors"), pursuant to which BioLight and the New ... IOPtima Ltd. subsidiary ("IOPtima") via a private placement. The ... of its innovative IOPtimate™ system used in the treatment ... approval pathway process for the IOPtimate™ system with the ...
Breaking Medicine Technology: