Navigation Links
Antidepressants Linked to Lower Child Suicide Rates

Researchers report an inverse relationship between antidepressant prescriptions and the rates of suicide in children// and adolescents -- a finding that contradicts the Food and Drug Administration's "black box" warning for selective serotonin reuptake inhibitor medications, also known as SSRI drugs.

The University of Illinois at Chicago epidemiologic study appears in the November issue of the American Journal of Psychiatry.

The researchers examined suicide rates of children ages 5-14 in each county of the United States from 1996 to 1998 and county-level data on SSRI prescriptions. The results were adjusted for sex, race, income, access to quality mental health care and variations in county-to-county suicide rates.

"We found that counties with the highest prescription rates for SSRI drugs had the lowest suicide rates in children and adolescents," said the lead author Robert Gibbons, director of the Center for Health Statistics and professor of biostatistics and psychiatry at UIC. "This is just the opposite of what you would predict if SSRI's were producing suicide."

There were 933 suicides among children ages 5-14 from 1996 to 1998, or an overall annual rate of 0.8 per 100,000. The researchers found that in counties with low antidepressant prescription rates, the suicide rate was as high as 1.7 per 100,000. In counties with high antidepressant prescription rates, the suicide rate was as low as 0.7 per 100,000.

The study predicts that if there were no SSRI prescriptions, there would be 253 more suicides per year among children and adolescents in the United States.

According to Gibbons, who was a member of the 2004 FDA advisory panel that voted 15-8 in favor of placing a black box warning on SSRI prescriptions, some experts fear that "doctors, particularly general practitioners, would be terrified of prescribing SSRI drugs for children" because the antidepressants are believed to cause suicidal tho ughts and behavior.

Since the black box warning was issued, the rate of antidepressant prescriptions in children has decreased by approximately 30 percent, said Gibbons.

"The big concern is that the rate of suicide will increase, not only in the United States, but in the world," Gibbons said. "What our study shows is support for that idea."

The study also found that adjusted suicide rates were highest in less densely populated areas of the western United States, which often include areas with Indian reservations. The adjusted suicide rates were lowest in large cities such as Chicago, New York, Boston, Los Angeles, San Diego, Seattle and Miami.

"It is very important that we develop better tools and a greater interest in this country in post-marketing surveillance of drugs," said Gibbons, who suggests a systematic and rigorous follow-up of prescription drugs to discover adverse event associations as early as possible to avoid making decisions about drugs based on very preliminary, or biased, data.

Source-Newswise
'"/>




Related medicine news :

1. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
2. Antidepressants increase gastric bleeding
3. Antidepressants-important role
4. Antidepressants increase gastric bleeding
5. Antidepressants could pose grave implications
6. Antidepressants May Benefit Heart Patients
7. Antidepressants Harmful for Kids
8. Antidepressants For Children: How safe is it ?
9. Antidepressants Late In Pregnancy Harmful to Unborn Baby
10. Antidepressants Could Lead To Abnormal Bleeding
11. Young Patients On Antidepressants Found To Be Associated With Suicidal Tendencies
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2016)... ... February 13, 2016 , ... Good news ... first in the area to offer AngioPlex™ Optical Coherence Tomography (OCT) Angiography, imaging ... as macular degeneration, diabetic retinopathy, and other vascular conditions. , In just a ...
(Date:2/13/2016)... (PRWEB) , ... February 13, 2016 , ... With FCPX ... overlays to footage all within Final Cut Pro X. Each user can select from ... 3D rotation, angle of view, blur, focus offset, hue, saturation, value, contrast, glow, and ...
(Date:2/13/2016)... ... ... In the early or “honeymoon” stage of a relationship, couples strive to ... way to be romantic, and may exaggerate a strength or two in an effort ... , A recent study from Queendom.com , however, suggests that new couples ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... new initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop the advanced skills needed to ... students from U.S. universities who will draw from Siemens’ deep knowledge of ...
(Date:2/12/2016)... ... February 12, 2016 , ... As a former television executive, owner Tal Rabinowitz ... no time to decompress, Rabinowitz found herself drawn to a casual meditation class while ... on her life, implementing a 20-minute-per-day meditation practice with her team. After her tenure ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... ALEXANDRIA, Va. , Feb. 12, 2016  This ... & Specialty Pharmacy (JMCP) takes an in-depth look ... the recent spike in prescription drug spending, which has ... JMCP Editor-in-Chief Laura E. Happe ... Laura E. Happe , PharmD, MPH. --> ...
(Date:2/12/2016)... , February 12, 2016 /PRNewswire/ ... nicht anders vermerkt)   http://www.sedar.com ... http://www.telestatherapeutics.com abrufbar.    --> ... des Unternehmens http://www.telestatherapeutics.com abrufbar.    ... (TSX:TST; PNK:BNHLF) veröffentlichte heute seinen Konzernabschluss des ...
(Date:2/12/2016)... VIEJO, Calif. , Feb. 12, 2016  Sequent ... enrollment in a study to evaluate the safety and ... for the treatment of ruptured intracranial aneurysms.  Prof ... University Hospital, in Paris, France ... first patient. France and ...
Breaking Medicine Technology: