Navigation Links
Anticancer Properties of Vitamin D Could Be Separated From Other Functions

Researchers at Georgetown University’s Lombardi Comprehensive Cancer Center have managed to separate the anti-cancer properties of Vitamin D from its other functions like bone development. //It is generally accepted that Vitamin D helps protect against colorectal cancer, but high dosage intended to take advantage of its anticancer properties might lead to calcium toxicity.

“We found that we might be able to separate the two functions at the molecular level, and this raises the possibility that vitamin D can be chemically modified into a drug that will only have anticancer effects,” said Professor Stephen Byers, Ph.D. Byers led a team of international researchers in collaboration with Salimuddin Shah, Ph.D. for this study. The findings are published in the journal Molecular Cell. It was found that that mutant forms of the protein that initiate binding with Vitamin D prevent it from exerting its effects on bone development and calcium transport, but do not hinder its anti-cancer property contained in a protein known as beta catenin. “We know beta catenin is also involved in regulation of hair growth and we wondered if these particular mutations might also allow the receptor to regulate beta catenin,” Byers said. “We found a mutation which caused rickets but not alopecia but which still allowed beta catenin to bind to the vitamin D receptor.” If indeed a drug highlighting the anti-cancer property of the vitamin can be developed, it could be useful in early stage cancers, but not in advanced or terminal cancers, “That’s because we know that by the time colon cancer is well advanced it fails to respond to vitamin D," Byers stressed. Contact: Liz McDonald eem6@georgetown.edu 202-687-5100 Georgetown University Medical Center Source: Eurkalert
'"/>




Page: 1

Related medicine news :

1. Anticancer Properties of Vitamin D Revealed
2. GSK’s New Anticancer Drug A Huge Success In Drug trail
3. Anticancer Effects of Curcumin Revealed
4. Compounds Found In The Vegetable Broccoli Could Have Anti-Cancer Properties
5. Stem Cells, Tumor Cells Share Similar Properties: Scope For Treatment and Prevention?
6. Anticancer Properties of Vitamin D Revealed
7. Tomatoes Have Stroke and Heart Attack Prevention Properties
8. A Plant Used By Ancient Britons Found To Have Properties To Fight Cancer
9. The Anti-HIV Properties Of Green Tea Uncovered
10. Botox Has Cramp Healing Properties
11. Vitamin B12 can help in detecting cancers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... ... September 20, 2017 , ... The ... “Humans With Vaginas.” The goal is to ignite conversation via social media and ... products. The brand has declared September “Humans with Vaginas” month, releasing a video ...
(Date:9/20/2017)... , ... September 20, 2017 , ... ... of older Americans at risk of price gouging for their prescription drugs, according ... (TSCL) . “Because Medicare isn’t negotiating on our behalf, there’s no consistency in ...
(Date:9/20/2017)... ... , ... “The Trials I Face to Receive God’s Grace”: a mesmerizing ... and goals to better one’s life through God. “The Trials I Face to Receive ... the wrong places, found a love for writing. Green feels that expressing his feelings ...
(Date:9/20/2017)... Texas (PRWEB) , ... September 20, 2017 , ... Houston, ... entire team took Friday, September 8, and Monday, September 11, off work and rolled ... Second Baptist Church before heading to local homes to start the process of rebuilding. ...
(Date:9/20/2017)... ... 2017 , ... “The Foggy Road to Moorwick”: the adventures of a young Scottish girl yearning ... author, Jeanine Liston, a busy mother of five who used her time waiting for children ... book for over twenty years. It was a way to give some meaning to ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... 6, 2017  Medical professionals are expected ... while treating their patients. Medical simulations offer ... involving patients. Simulation provides a safe method ... out procedures, refine techniques and build confidence, ... new technology, such as augmented reality, will ...
(Date:9/5/2017)... , Sept. 5, 2017  Xyntek Inc. has announced another milestone in ... new Midwest office to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West ... ... customer engagements regionally. ...
(Date:9/1/2017)... 1, 2017  Explorers Like Us ( https://explorerslikeus.com/ ) is ... experiences — and deliver these experiences as part of Life ... feel and heal better. ... While nothing beats a walk, jog or simply ... Life Environments™ is the next best thing when getting there ...
Breaking Medicine Technology: