Navigation Links
Anticancer Properties of Vitamin D Could Be Separated From Other Functions

Researchers at Georgetown University’s Lombardi Comprehensive Cancer Center have managed to separate the anti-cancer properties of Vitamin D from its other functions like bone development. //It is generally accepted that Vitamin D helps protect against colorectal cancer, but high dosage intended to take advantage of its anticancer properties might lead to calcium toxicity.

“We found that we might be able to separate the two functions at the molecular level, and this raises the possibility that vitamin D can be chemically modified into a drug that will only have anticancer effects,” said Professor Stephen Byers, Ph.D. Byers led a team of international researchers in collaboration with Salimuddin Shah, Ph.D. for this study. The findings are published in the journal Molecular Cell. It was found that that mutant forms of the protein that initiate binding with Vitamin D prevent it from exerting its effects on bone development and calcium transport, but do not hinder its anti-cancer property contained in a protein known as beta catenin. “We know beta catenin is also involved in regulation of hair growth and we wondered if these particular mutations might also allow the receptor to regulate beta catenin,” Byers said. “We found a mutation which caused rickets but not alopecia but which still allowed beta catenin to bind to the vitamin D receptor.” If indeed a drug highlighting the anti-cancer property of the vitamin can be developed, it could be useful in early stage cancers, but not in advanced or terminal cancers, “That’s because we know that by the time colon cancer is well advanced it fails to respond to vitamin D," Byers stressed. Contact: Liz McDonald eem6@georgetown.edu 202-687-5100 Georgetown University Medical Center Source: Eurkalert
'"/>




Page: 1

Related medicine news :

1. Anticancer Properties of Vitamin D Revealed
2. GSK’s New Anticancer Drug A Huge Success In Drug trail
3. Anticancer Effects of Curcumin Revealed
4. Compounds Found In The Vegetable Broccoli Could Have Anti-Cancer Properties
5. Stem Cells, Tumor Cells Share Similar Properties: Scope For Treatment and Prevention?
6. Anticancer Properties of Vitamin D Revealed
7. Tomatoes Have Stroke and Heart Attack Prevention Properties
8. A Plant Used By Ancient Britons Found To Have Properties To Fight Cancer
9. The Anti-HIV Properties Of Green Tea Uncovered
10. Botox Has Cramp Healing Properties
11. Vitamin B12 can help in detecting cancers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/23/2017)... ... February 23, 2017 , ... Dr. David Mahon leads Siena Dental, a ... Mahon was named a 2017 Top Patient Rated Henderson Dentist by Find ... that recognizes local physicians and dentists who have earned high ratings and superior patient ...
(Date:2/23/2017)... ... February 23, 2017 , ... The Center for Autism ... Consortium for Autism Research and Treatment (RI-CART) and Cinemaworld to present Sensory Friendly ... (ASD) to see films in an environment that accommodates their unique needs. , ...
(Date:2/23/2017)... ... 23, 2017 , ... HealthPostures, the desk for standing designer headquartered in Prior ... to the Minneapolis Home and Garden Show which is being held February 24 through ... attention is the Minneapolis Convention Center. , From its broad line of sit ...
(Date:2/22/2017)... , ... February 22, 2017 , ... Gevir, a New ... antler velvet, announced its products are coming soon to Amazon.com, the world’s largest online ... Thomson as a means to develop an effective natural treatment for Shelley’s Multiple Sclerosis, ...
(Date:2/22/2017)... ... 22, 2017 , ... South Bend’s Lunkerville, the award-winning TV series that catches ... The Water (HOW), a non-profit organization dedicated to helping military veterans relax, rehabilitate, and ... D’ traveling to Lake Denmark, New Jersey, to fish with war veteran Justin Vail ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... York , February 23, 2017 ... Holter Monitor Market are GE Healthcare, Koninklijke Philips N.V., ... about 48% in the global market in 2015. Strong ... two key factors assessed to be aiding these players ... Research states that the players in the global market ...
(Date:2/23/2017)... Mass. , Feb. 23, 2017   ... partner to global in vitro diagnostics manufacturers and ... series titled "Catalyzing Implementation of NGS-Based Tests" to ... March 30, 2017 at 11am Eastern Standard Time ... is to highlight the need for improved performance ...
(Date:2/23/2017)... MabVax Therapeutics Holdings, Inc . ... announces that it has received notice from the ... initiation a Phase I clinical trial with MVT-1075 ... ( 177 Lu-CHX-A?-DTPA-HuMab5B1) is the Company,s novel fully ... the phase I clinical trial in patients with ...
Breaking Medicine Technology: