Navigation Links
Antibodies in Mother Affect Heart of Fetus

A study conducted in 100 pregnant women with anti-Ro and anti-La antibodies revealed development of heart problems in fetus that could be treated in early stages//.

There is an increased risk of fetal heart problems when mothers carry particular antibodies associated with rheumatic diseases, according to an abstract presented by Yale School of Medicine researchers at the Society for Maternal-Fetal Medicine Conference February 9 in San Francisco.

Congenital heart block (CHB) is present at or before birth and impairs the heart's electrical signaling from the upper to the lower chambers. CHB carries a 20 percent death rate and nearly all survivors require pacemakers. Joshua Copel, M.D., professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale helped conduct the PR Interval and Dexamethasone Evaluation (PRIDE) study with a team of other researchers to evaluate an early marker of cardiac injury before there is permanent scarring.

The PRIDE group conducted a longitudinal (observational) study following over 100 women with the anti-Ro and anti-La antibodies to determine if there were early signs of fetal heart problems. They also explored whether early treatment would reverse the problems.

The team found that while first-degree fetal heart block may be reversible with the steroid drug dexamethasone, the condition could advance within as little as one week to a third-degree block, which is irreversible even with further intervention.

"Given the high recurrence rate we confirmed in this study, close monitoring and the earliest possible marker is necessary," said Copel, who plans trials of other possible treatments. "Advanced block and permanent heart damage can occur within one week of a normal echocardiogram, even a weekly evaluation may not be sufficient to detect early onset of disease."

Source-Eurekalert
PRI
'"/>




Page: 1

Related medicine news :

1. Antibodies to fight HIV infection.
2. Heparin Antibodies May Put Patients At Risk
3. Survival of Mice With Human Breast Cancer Extended by Monoclonal Antibodies
4. Scientists Develop Antibodies from Plant Seeds
5. Mothers with periodontitis may deliver premature babies
6. Changing Partners may put Expectant Mothers at Risk
7. Link Between Mothers Depression and Violence in Children
8. Drug to stop HIV spread to babies may Indirectly harm The Mother
9. Mother’s Diet Could Prevent Cancer In Their Unborn Children
10. Mother’s Milk Stored For Long Periods Found To Have Less Antioxidant
11. Vaginal Birth After C-section Dangerous For Both Mother And Baby
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... The Radiology Business Management Association (RBMA) ... annual awards, now in their 12th year, are among the most prestigious in radiology ... 2016, the awards were retooled to recognize achievements in both large budget (over $5,000) ...
(Date:3/24/2017)... ... March 24, 2017 , ... The iaedp Foundation, the premier provider of educational ... those suffering from the full spectrum of disordered eating, announced today that the 2017 ... nearly all 50 states and several countries converged on the Green Valley Resort in ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... its innovative EcoQube Frame vertical micro-veggies garden on Kickstarter . Surpassing the ... product – with nearly 2,000 consumers (and counting) already backing the campaign. ...
(Date:3/24/2017)... ... 24, 2017 , ... On June 9, 2017, Cassie Springer ... seminar in Chicago, Illinois. She will present on: , Filing Benefit Claims—Responding ... ERISA involve claims for long-term disability benefits. This session will address the ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... ( http://www.hygieacare.com ) announced their partnership to prep patients for colonoscopy at the ... Endoscopy Centers in 87th Ave., Miami, FL. , The HyGIeaCare® Prep, ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... PUNE, India , March 24, 2017 ... Stimulators Market: Global Opportunity Analysis and Industry Forecast, 2014-2022," the spine bone stimulators ... $724 million by 2022, growing at a CAGR of 3.6% during the forecast ... ... Allied Market Research Logo ...
(Date:3/24/2017)... , Mar. 24, 2017 Research and Markets has ... Development, Growth and Demand Forecast to 2022" report to their offering. ... The global wound care ... grow at a CAGR of 6.7% during 2016-2022 Among the ... the largest share in the global market in 2015. Among the various ...
(Date:3/24/2017)... March 24, 2017   The Accreditation Council ... medical affairs in the pharmaceutical industry has appointed ... of a newly formed scientific advisory board. Dr. ... form the first ever medical affairs think tank ... information about the ACMA, please visit  www.medicalaffairsspecialist.org .  ...
Breaking Medicine Technology: