Navigation Links
Anti-inflammatory Drug Fails to Improve COPD Symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease , or COPD, in a large, multi-center trial.

The results of the randomized, double-blind, placebo-controlled trial of infliximab were published in the first issue of the May American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

According to an editorial commenting on the research, the failure of the infliximab to provide any therapeutic benefit in COPD patients was unexpected because the drug has proven effective in treating other inflammatory diseases, particularly rheumatoid arthritis and Crohn's disease.

COPD is the fourth-leading cause of death of men and women in the United States and the world. It is projected to become the third-leading cause of death, after heart disease and cancer, by 2015.

Stephen I. Rennard, M.D., of the University of Nebraska Medical Center in Omaha, led a team of researchers at 41 U.S. medical centers that enrolled 234 subjects in the study. Patients receiving infliximab were randomly selected to receive the drug in doses of 3 mg/kg or 5 mg/kg six times during a six-month period of time.

At the end of six months, there was no meaningful difference in the quality of life among those taking the drug and those taking the placebo as measured by the Chronic Respiratory Questionnaire (CRQ). The questionnaire, which was the primary endpoint, assesses health-related quality of life in patients with functionally limiting chronic lung disease.

There were also no differences among the three groups in secondary efficacy endpoints as measured by FEV1, 6-minute walk distance, the transition dyspnea index and the number of exacerbations requiring a doctor or hospital visit.

According to the authors, the results of the study were surprising for a number of reasons. Infliximab is an anti
'"/>




Page: 1 2

Related medicine news :

1. Anti-inflammatory drugs reduce the risk of oral cancer for smokers
2. Protein Secreted By Worm Eggs Holds Key To Anti-inflammatory Therapy
3. Anti-inflammatory Drug Fails to Improve COPD Symptoms
4. Anti-inflammatory Drugs Interact With Hormone Replacement Therapy
5. Alcoholism Drug Fails To Prevent Drinking Relapses
6. Tamiflu Fails To Save Two Lives
7. Himachal Pradesh Fails To Become Health Tourism Center
8. Budhias Medical Report Fails to Address Long Term Health Issues
9. "Daydreaming" Network Fails In Autism
10. 72-year-old Bachelor of Rajasthan Fails Class 10 Again!
11. Already Short Staffed And In Deficit NHS Fails To Supply Staff For IT Project
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Anti inflammatory Drug Fails Improve COPD Symptoms

(Date:8/21/2014)... According to new market research ... Food & Beverage, Personal care & Pharmaceutical) & ... Electronics, Textile) & Geography - Global Trends & ... polylactic acid markets and segments with analyses and ... on their sub-segments, in terms of value and ...
(Date:8/21/2014)... San Luis Obispo, CA (PRWEB) August 21, 2014 ... July/August edition of Current Pedorthics, a bi-monthly publication of the ... the field of pedorthics. , Bunion Bootie ... as an alternative solution for bunion sufferers and their pain. ... be worn in nearly any shoe to eliminate the friction ...
(Date:8/21/2014)... WA (PRWEB) August 21, 2014 While ... Grant, found it hard to stay focused on his ... and mosquitoes. The constant whine, slapping and continual need ... researching innovative methods to stay protected from insects while ... successful career in the Financial Services/Investment Banking Industry, decided ...
(Date:8/21/2014)... 2014 Atlantic Information Services, Inc. (AIS) ... News and The AIS Report on Blue Cross & ... Blue Shield Association or its member companies) — is ... in AIS’s Management Insight Series. Bundled Payment Models: ... two insurers — Horizon Healthcare Services, Inc. and Arkansas ...
(Date:8/21/2014)... 2014 AttorneyOne.com, a recognized authority on ... information from the FDA on Dianeal Low Calcium ... announced on August 15, that two lots of Dianeal ... 5000mL (Ambu-Flex II), by Baxter International Inc., are ... , The reason for the recall is the ...
Breaking Medicine News(10 mins):Health News:Lactic Acid Market Worth $3,577.5 Million & Polylactic Acid Market Worth $4,840.1 Million by 2019 – New Report 2Health News:Lactic Acid Market Worth $3,577.5 Million & Polylactic Acid Market Worth $4,840.1 Million by 2019 – New Report 3Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 2Health News:Recently Featured in Current Pedorthics: Bunion Bootie, the Very Popular Bunion Treatment Splint 3Health News:Financial VP Fights Pesky Bugs with Launch of Biteback Sports Insect Shield® Golf Apparel 2Health News:New AIS Report Highlights Two Case Studies of Bundled Payment Models 2Health News:Dianeal Low Calcium (2.5mEq/L) Peritoneal Dialysis Solution with 2.5% Dextrose 5000mL (Ambu-Flex II) Recalled: AttorneyOne Monitors and Keeps Consumers Informed 2
... humans are genetically more suited to being vegetarians than meat-eaters ... conference by more then 300 leading scientists from New Zealand ... finding a cure for cancer is also under discussion at ... Convener of the conference says the finding that a human ...
... drawer, the time-honored lessons of helping organize one’s clothes learned ... to encode such categories as socks, shirts, or any other ... research from Harvard Medical School (HMS) investigators has identified an ... report in the advanced online Nature that they have identified ...
... Palmerston North high school, 500 will undergo testing this week ... students will be tested in the coming weeks. ... and laboratory tests have now confirmed the boy has tuberculosis. ... and parents revealed exposure to the infecting bacteria. The remaining ...
... skin lightening products are available over the counter but the ... over the counter skin lighteners that contain hydroquinone because studies ... causing. ,Dermatologist, Dr. Mathew Avram, of Massachusetts General Hospital ... here. I think they haven't seen the data to show ...
... that studies that were being conducted towards pest control ... ,Researchers from the University of California, have stated ... been identified by researchers who were initially looking for ... for people suffering from arthritis and other inflammatory diseases. ...
... present in almost every medicine cabinet, may help in easing ... Clinic.// ,Aspirin is known to help in the ... of cancer along with headaches. The researchers say that now ... to have been connected with enlarged prostates. ,It ...
Cached Medicine News:Health News:Brain's Filing System Uncovered 2Health News:Brain's Filing System Uncovered 3Health News:Pest Control research Leads to Pain Control Discovery 2Health News:Pest Control research Leads to Pain Control Discovery 3
(Date:8/20/2014)... -- Research and Markets  has announced the addition of ... their offering. Global Market Report of Pralmorelin ... and regionally ( Europe , Asia ... Latin America etc.). It captures Pralmorelin market trends, ... on three primary areas; manufacture methods & technology development, market ...
(Date:8/20/2014)... Ariz. , Aug. 20, 2014   ... the  Roche  Group, today announced that its VENTANA ... CE marked in the European Union for routine ... The system, consisting of VENTANA Virtuoso software coupled ... VENTANA iScan HT slide scanner, provides automated digital ...
(Date:8/20/2014)... PHOENIX , Aug. 20, 2014 /PRNewswire-USNewswire/ ... next-generation sequencing and proteomic diagnostics and biomarker driven ... collaboration with TESARO, Inc.  Paradigm will use its ... from clinical trials to better predict which patients ... may lead to more successful clinical trial outcomes ...
Breaking Medicine Technology:Global Market Report of Pralmorelin 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3Paradigm Announces Molecular Profiling Collaboration with TESARO, Inc. 2
... The BiPAP Pro with Bi-Flex bi-level system, ... that the BiPAP Pro takes to change ... Digital Auto-Trak Sensitivity™ which automatically triggers the ... pressures based on the patients breathing rhythm. ...
... Electrophoresis System (PGGE) is designed to ... density lipoproteins (LDL) and high density ... using nondenaturing pore gradient gel electrophoresis. ... short DNA sequencing runs. Temperature control ...
This control is intended for monitoring cell counts in patient cerebrospinal fluid samples, performed manually using a hemocytometer. Spinalscopics is fortified to target levels with purified chemica...
... Suitable for use with Leica ... bilirubinometers (pediatric) and all automated ... including Aeroset, AU Series, Cobas, ... These controls contain purified bilirubin ...
Medicine Products: