Navigation Links
Anti-fungal drug - Griseofulvin may help treat cancer

An antifungal drug called griseofulvin has been around now for almost 40 years for treatment skin // fungal infections. It has now been discovered that it maybe useful in treating cancer as it has been shown to inhibit growth of cancer cells in the lab. This was reported by international team of scientists. Leslie Wilson, professor of biochemistry and pharmacology at the University of California, Santa Barbara, The results are published in online edition of the Proceedings of the National Academy of Sciences.

Griseofulvin can be applied as an ointment to treat skin fungal infection like ringworm can now be given orally. "The drug has remarkably few side effects and has been used for a long time, we discovered that it has the ability to inhibit the growth of cancer cells, in a manner that is similar to much more powerful anticancer drugs such as taxol and vinblastine," said Wilson. "Although the anti-cancer activity is weak, it is already approved for human use and could be used along with more powerful anticancer agents as an adjuvant in cancer chemotherapy."

The authors found that the drug works as an anti-proliferative agent and inhibits cancer cells by affecting mitosis, or cell division, and mitotic spindle microtubule function. The authors conclude by saying- "A mild suppression of microtubule dynamics by griseofulvin in tumor cells, combined with the effects of more powerful drugs working through other mechanisms, might provide a therapeutic advantage for treatment of certain tumors."

The work is a collaborative work between Wilson's lab, in UCSB's Department of Biochemistry, Molecular, Cellular and Developmental Biology, and the lab in the School of Biosciences and Bioengineering of the Indian Institute of Technology Bombay, in India.
'"/>




Page: 1

Related medicine news :

1. Anti-fungal Drug Block Angiogenesis
2. Thyroid hormone treatment hastens recovery after cardiac surgery
3. Feeding channel created by malaria parasite - a new target for malaria treatments
4. New drug to treat Heart Attack and damaged tissue
5. Now umbilical cord helps in stroke treatment.
6. Now AIDS treatment comes dirt-cheap
7. Breast cancer treatment to be determined by gene test
8. Hemopurifier may revolutionise AIDS treatment
9. New drug helps boost cancer treatment
10. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
11. Experimental treatment for Ebola Virus Shows promising results in mice
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... June 23, 2017 , ... Everybody has their own ... others prefer to read it, and some people don't like it at all. FindaTopDoc ... what they found: , Erotic literature can give readers a taste of their deepest, ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Aesthetic Channel has recently ... Talei has come up with a proprietary technique that he calls the AuraLyft ... have dropped. For all ages, patients can expect to look refreshed, rejuvenated, and revitalized. ...
(Date:6/23/2017)... ... 2017 , ... Georgia State University will host the First ... two-day conference is focused on advancing scientific knowledge about the aggressive triple negative ... racial breast cancer-related disparities. The conference theme is “Illuminating Actionable Biology.” , Conference ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... MD ... Florida. This is MD Now’s 28th facility overall and marks the urgent care center's ... located one mile North of The Falls shopping mall. The new clinic offers a ...
(Date:6/23/2017)... ... 23, 2017 , ... Ross Insurance Agency ( http://www.rossinsuranceagency.com ) ... Management Agency’s (FEMA) recent update of flood zones, more people than ever are ... was enacted to reflect the actual risk in flood zone areas during a ...
Breaking Medicine News(10 mins):
(Date:5/30/2017)... May 30, 2017 Therapix Biosciences Ltd. (Nasdaq: ... in the development of cannabinoid-based drugs, today announced ... overview at three upcoming scientific and investor conferences ... Micro Invitational: ... Date:                     Wednesday, ...
(Date:5/26/2017)...  In response to the opioid epidemic in ... working with Pfizer to make up to 1 million ... community health centers, free and charitable clinics, public health ... "Pfizer has a long-standing commitment to improving health outcomes ... through educational activities," said Caroline Roan , vice ...
(Date:5/22/2017)... , May 22, 2017  Lilac Corp, the ... announces the launch of a new website ... results of a clinical study that showed surprising ... with Gene-Eden-VIR/Novirin in individuals suffering from HPV warts, ... that there are no other treatments that clear ...
Breaking Medicine Technology: