Navigation Links
Anti-fungal drug - Griseofulvin may help treat cancer

An antifungal drug called griseofulvin has been around now for almost 40 years for treatment skin // fungal infections. It has now been discovered that it maybe useful in treating cancer as it has been shown to inhibit growth of cancer cells in the lab. This was reported by international team of scientists. Leslie Wilson, professor of biochemistry and pharmacology at the University of California, Santa Barbara, The results are published in online edition of the Proceedings of the National Academy of Sciences.

Griseofulvin can be applied as an ointment to treat skin fungal infection like ringworm can now be given orally. "The drug has remarkably few side effects and has been used for a long time, we discovered that it has the ability to inhibit the growth of cancer cells, in a manner that is similar to much more powerful anticancer drugs such as taxol and vinblastine," said Wilson. "Although the anti-cancer activity is weak, it is already approved for human use and could be used along with more powerful anticancer agents as an adjuvant in cancer chemotherapy."

The authors found that the drug works as an anti-proliferative agent and inhibits cancer cells by affecting mitosis, or cell division, and mitotic spindle microtubule function. The authors conclude by saying- "A mild suppression of microtubule dynamics by griseofulvin in tumor cells, combined with the effects of more powerful drugs working through other mechanisms, might provide a therapeutic advantage for treatment of certain tumors."

The work is a collaborative work between Wilson's lab, in UCSB's Department of Biochemistry, Molecular, Cellular and Developmental Biology, and the lab in the School of Biosciences and Bioengineering of the Indian Institute of Technology Bombay, in India.
'"/>




Page: 1

Related medicine news :

1. Anti-fungal Drug Block Angiogenesis
2. Thyroid hormone treatment hastens recovery after cardiac surgery
3. Feeding channel created by malaria parasite - a new target for malaria treatments
4. New drug to treat Heart Attack and damaged tissue
5. Now umbilical cord helps in stroke treatment.
6. Now AIDS treatment comes dirt-cheap
7. Breast cancer treatment to be determined by gene test
8. Hemopurifier may revolutionise AIDS treatment
9. New drug helps boost cancer treatment
10. Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis
11. Experimental treatment for Ebola Virus Shows promising results in mice
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... ... 27, 2016 , ... More than a third of American adults are considered ... surgery has received increased attention in recent years, as an article published ... weight loss, most people are familiar with the basic requirements of maintaining a healthy ...
(Date:5/27/2016)... York, NY (PRWEB) , ... May 27, 2016 , ... ... campaign returns for a third time to shed lights on the variety of topics ... and inspirational stories, “Nurse Appreciation” tackles why this career has gone from being in ...
(Date:5/27/2016)... ... May 27, 2016 , ... In ... the many who are unaware of the plight of aphasia. In collaboration with ... the “Stroke Awareness” campaign. , The link between stroke and aphasia is relatively ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... in scholarships to students studying complementary medicine. Allison Outerbridge is this year’s ... her award on May 18 at the university’s Student Leadership Awards ceremony. , ...
(Date:5/26/2016)... , ... May 26, 2016 , ... W.S. Badger ... has been honored with a 2016 When Work Works Award for its use of ... of the national When Work Works project administered by the Families and Work Institute ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)...   , Study met ... bowel cleansing and superiority in , ... of the ascending colon   ... Norgine B.V. today announced new positive data from the phase ... preparation) versus standard 2 litre PEG with ascorbate. The study met ...
(Date:5/24/2016)... May 24, 2016  NxStage Medical, Inc. (Nasdaq: ... on advancing renal care, today announced that Jeffrey ... in the following schedule of investor conferences. Where applicable, ... at http://ir.nxstage.com/ .   ... Conference NY, NY           Friday, June 10, 2016 1:30 ...
(Date:5/24/2016)... HONG KONG , May 24, 2016 ... , the world , s ... and AV fistula intervention   OrbusNeich, a ... solutions, has expanded its portfolio to include products to ... balloons are the company,s first entry devices for lower ...
Breaking Medicine Technology: