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Anti Inflammatory Evaluation Of Plumeria Acuminata Leaves

n, histamine and serotonin respectively. Administration of MEPA (500 mgkg-1 b.w) and indomethacin (10 mgkg-1 b.w) significantly reduced the formation of granuloma tissue induced by cotton pellet method at a rate of 45.06 and 51.57% respectively. The effect produced by the extract was comparable to that of indomethacin a prototype of a nonsteroidal anti-inflammatory agent.

Conclusion

The results obtained in this study indicated that the methanol extract of Plumeria Acuminata possess potent anti-inflammatory activity in both acute and chronic models.
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